Effectiveness of Renal Denervation for Treatment of Resistant Hypertension: an Evidence-based Case Report

Aim: to determine whether the renal sympathetic – nerve ablation method is more effective compared to multiple anti – hypertensive drug among patients with resistant hypertension. Methods: a search was conducted on PubMed. The selection of title and abstract was conducted using inclusion and exclus...

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Main Authors: Minarma Siagian, Aldo Ferly, Arinna Irianti, Arky Kurniati, Florence Low, Ras A. Riza
Format: Article
Language:English
Published: Interna Publishing 2014-10-01
Series:Acta Medica Indonesiana
Online Access:https://www.actamedindones.org/index.php/ijim/article/view/111
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author Minarma Siagian
Aldo Ferly
Arinna Irianti
Arky Kurniati
Florence Low
Ras A. Riza
author_facet Minarma Siagian
Aldo Ferly
Arinna Irianti
Arky Kurniati
Florence Low
Ras A. Riza
author_sort Minarma Siagian
collection DOAJ
description Aim: to determine whether the renal sympathetic – nerve ablation method is more effective compared to multiple anti – hypertensive drug among patients with resistant hypertension. Methods: a search was conducted on PubMed. The selection of title and abstract was conducted using inclusion and exclusion criteria, which led to five relevant articles. The selected studies were critically appraised for its validity, importance and applicability. Results: one of studies showed that renal denervation is not effectively reduced blood pressure in patients with resistant hypertension; nevertheless other studies showed significant results. Conclusion: literature with strongest evidence showed that there is no relationship between renal sympathetic-nerve ablation procedure and reduction of blood pressure. However, as there is still some methodological flaw on the literature, we recommend doing another study that may find the appropriate results. Key words: renal denervation, resistant hypertension.
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institution Kabale University
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publishDate 2014-10-01
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series Acta Medica Indonesiana
spelling doaj-art-dd9a6446050e4dfa993fd59e445efbe32025-08-20T03:35:47ZengInterna PublishingActa Medica Indonesiana0125-93262338-27322014-10-01464Effectiveness of Renal Denervation for Treatment of Resistant Hypertension: an Evidence-based Case ReportMinarma Siagian0Aldo Ferly1Arinna Irianti2Arky Kurniati3Florence Low4Ras A. Riza5Department of Physiology, Faculty of Medicine Universitas Indonesia, Jakarta, IndonesiaFaculty of Medicine Universitas Indonesia, Jakarta, IndonesiaFaculty of Medicine Universitas Indonesia, Jakarta, IndonesiaFaculty of Medicine Universitas Indonesia, Jakarta, IndonesiaFaculty of Medicine Universitas Indonesia, Jakarta, IndonesiaFaculty of Medicine Universitas Indonesia, Jakarta, Indonesia Aim: to determine whether the renal sympathetic – nerve ablation method is more effective compared to multiple anti – hypertensive drug among patients with resistant hypertension. Methods: a search was conducted on PubMed. The selection of title and abstract was conducted using inclusion and exclusion criteria, which led to five relevant articles. The selected studies were critically appraised for its validity, importance and applicability. Results: one of studies showed that renal denervation is not effectively reduced blood pressure in patients with resistant hypertension; nevertheless other studies showed significant results. Conclusion: literature with strongest evidence showed that there is no relationship between renal sympathetic-nerve ablation procedure and reduction of blood pressure. However, as there is still some methodological flaw on the literature, we recommend doing another study that may find the appropriate results. Key words: renal denervation, resistant hypertension. https://www.actamedindones.org/index.php/ijim/article/view/111
spellingShingle Minarma Siagian
Aldo Ferly
Arinna Irianti
Arky Kurniati
Florence Low
Ras A. Riza
Effectiveness of Renal Denervation for Treatment of Resistant Hypertension: an Evidence-based Case Report
Acta Medica Indonesiana
title Effectiveness of Renal Denervation for Treatment of Resistant Hypertension: an Evidence-based Case Report
title_full Effectiveness of Renal Denervation for Treatment of Resistant Hypertension: an Evidence-based Case Report
title_fullStr Effectiveness of Renal Denervation for Treatment of Resistant Hypertension: an Evidence-based Case Report
title_full_unstemmed Effectiveness of Renal Denervation for Treatment of Resistant Hypertension: an Evidence-based Case Report
title_short Effectiveness of Renal Denervation for Treatment of Resistant Hypertension: an Evidence-based Case Report
title_sort effectiveness of renal denervation for treatment of resistant hypertension an evidence based case report
url https://www.actamedindones.org/index.php/ijim/article/view/111
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