Group 2 innate lymphoid cells are a non-redundant source of interleukin-5 required for development and function of murine B1 cells

Group 2 innate lymphoid cells are a non-redundant source of interleukin-5 required for development and function of murine B1 cells

Abstract Tissue-resident immune cells, such as innate lymphoid cells, mediate protective or detrimental immune responses at barrier surfaces. Upon activation by stromal or epithelial cell-derived alarmins, group 2 innate lymphoid cells (ILC2s) are a rapid source of type 2 cytokines, such as IL-5. Ho...

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Main Authors: Karoline F. Troch, Manuel O. Jakob, Patrycja M. Forster, Katja J. Jarick, Jonathan Schreiber, Alexandra Preusser, Gabriela M. Guerra, Pawel Durek, Caroline Tizian, Nele Sterczyk, Sofia Helfrich, Claudia U. Duerr, David Voehringer, Mario Witkowski, David Artis, Tim Rollenske, Andrey A. Kruglov, Mir-Farzin Mashreghi, Christoph S. N. Klose
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-54780-3
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