Identification and Molecular Characterization of Telosma Mosaic Virus (TelMV) and East Asian Passiflora Virus (EAPV) from Patchouli in China

Patchouli is a valuable medicinal herb and cash crop in China, but viral infections cause significant yield losses. This study identified six viruses in patchouli transcriptome data, including the first-ever detection of East Asian Passiflora Virus (EAPV) in patchouli. RT-PCR validated three viruses...

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Main Authors: Asma Aziz, Na Li, Xiaoqing Wang, Linxi Wang, Yougen Wu, Muhammad Zeeshan Ul Haq, Zhaoji Dai, Hongguang Cui
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Viruses
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Online Access:https://www.mdpi.com/1999-4915/16/12/1837
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Summary:Patchouli is a valuable medicinal herb and cash crop in China, but viral infections cause significant yield losses. This study identified six viruses in patchouli transcriptome data, including the first-ever detection of East Asian Passiflora Virus (EAPV) in patchouli. RT-PCR validated three viruses from diseased patchouli plants in Haikou, China: telosma tosaic virus (TelMV), broad bean wilt virus-2 (BBWV-2), and pogostemom alphacytorhabdovirus 1 (PogACRV1_Pog). The complete genomic sequence of TelMV from patchouli (TelMV) was determined, revealing a 9691-nucleotide RNA genome encoding a 3083-amino-acid polyprotein. Comparative analysis showed 77.66% to 81.01% nucleotide sequence identity with previously reported TelMV isolates. TelMV was also shown to be infectious in <i>Nicotiana benthamiana</i> through sap rub-inoculation. Additionally, a large portion of the EAPV genome was reconstructed from RNA-seq data, with coat protein analysis confirming its identity. This study presents the first complete TelMV genome in patchouli and the first detection of EAPV in the plant.
ISSN:1999-4915