Clinical Practice Guidelines of the Russian Scientific Liver Society, Russian Gastroenterological Association, Russian Association of Endocrinologists, Russian Association of Gerontologists and Geriatricians and National Society for Preventive Cardiology on Diagnosis and Treatment of Non-Alcoholic Liver Disease

Aim: present clinical guidelines, aimed at general practitioners, gastroenterologists, cardiologists, endocrinologists, comprise up-to-date methods of diagnosis and treatment of non-alcoholic fatty liver disease.Key points. Nonalcoholic fatty liver disease, the most wide-spread chronic liver disease...

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Main Authors: V. T. Ivashkin, M. V. Maevskaya, M. S. Zharkova, Yu. V. Kotovskaya, O. N. Tkacheva, E. A. Troshina, M. V. Shestakova, I. V. Maev, V. V. Breder, N. I. Gheivandova, V. L. Doshchitsin, E. N. Dudinskaya, E. V. Ershova, Kh. B. Kodzoeva, K. A. Komshilova, N. V. Korochanskaya, A. Yu. Mayorov, E. E. Mishina, M. Yu. Nadinskaya, I. G. Nikitin, N. V. Pogosova, A. I. Tarzimanova, M. Sh. Shamkhalova
Format: Article
Language:Russian
Published: Gastro LLC 2022-12-01
Series:Российский журнал гастроэнтерологии, гепатологии, колопроктологии
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Online Access:https://www.gastro-j.ru/jour/article/view/777
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author V. T. Ivashkin
M. V. Maevskaya
M. S. Zharkova
Yu. V. Kotovskaya
O. N. Tkacheva
E. A. Troshina
M. V. Shestakova
I. V. Maev
V. V. Breder
N. I. Gheivandova
V. L. Doshchitsin
E. N. Dudinskaya
E. V. Ershova
Kh. B. Kodzoeva
K. A. Komshilova
N. V. Korochanskaya
A. Yu. Mayorov
E. E. Mishina
M. Yu. Nadinskaya
I. G. Nikitin
N. V. Pogosova
A. I. Tarzimanova
M. Sh. Shamkhalova
author_facet V. T. Ivashkin
M. V. Maevskaya
M. S. Zharkova
Yu. V. Kotovskaya
O. N. Tkacheva
E. A. Troshina
M. V. Shestakova
I. V. Maev
V. V. Breder
N. I. Gheivandova
V. L. Doshchitsin
E. N. Dudinskaya
E. V. Ershova
Kh. B. Kodzoeva
K. A. Komshilova
N. V. Korochanskaya
A. Yu. Mayorov
E. E. Mishina
M. Yu. Nadinskaya
I. G. Nikitin
N. V. Pogosova
A. I. Tarzimanova
M. Sh. Shamkhalova
author_sort V. T. Ivashkin
collection DOAJ
description Aim: present clinical guidelines, aimed at general practitioners, gastroenterologists, cardiologists, endocrinologists, comprise up-to-date methods of diagnosis and treatment of non-alcoholic fatty liver disease.Key points. Nonalcoholic fatty liver disease, the most wide-spread chronic liver disease, is characterized by accumulation of fat by more than 5 % of hepatocytes and presented by two histological forms: steatosis and nonalcoholic steatohepatitis. Clinical guidelines provide current views on pathogenesis of nonalcoholic fatty liver disease as a multisystem disease, methods of invasive and noninvasive diagnosis of steatosis and liver fibrosis, principles of nondrug treatment and pharmacotherapy of nonalcoholic fatty liver disease and associated conditions. Complications of nonalcoholic fatty liver disease include aggravation of cardiometabolic risks, development of hepatocellular cancer, progression of liver fibrosis to cirrhotic stage.Conclusion. Progression of liver disease can be avoided, cardiometabolic risks can be reduced and patients' prognosis — improved by the timely recognition of diagnosis of nonalcoholic fatty liver disease and associated comorbidities and competent multidisciplinary management of these patients.
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series Российский журнал гастроэнтерологии, гепатологии, колопроктологии
spelling doaj-art-dd8d46c28c8d40eaa988a9d566abc2f42025-02-10T16:14:37ZrusGastro LLCРоссийский журнал гастроэнтерологии, гепатологии, колопроктологии1382-43762658-66732022-12-0132410414010.22416/1382-4376-2022-32-4-104-140501Clinical Practice Guidelines of the Russian Scientific Liver Society, Russian Gastroenterological Association, Russian Association of Endocrinologists, Russian Association of Gerontologists and Geriatricians and National Society for Preventive Cardiology on Diagnosis and Treatment of Non-Alcoholic Liver DiseaseV. T. Ivashkin0M. V. Maevskaya1M. S. Zharkova2Yu. V. Kotovskaya3O. N. Tkacheva4E. A. Troshina5M. V. Shestakova6I. V. Maev7V. V. Breder8N. I. Gheivandova9V. L. Doshchitsin10E. N. Dudinskaya11E. V. Ershova12Kh. B. Kodzoeva13K. A. Komshilova14N. V. Korochanskaya15A. Yu. Mayorov16E. E. Mishina17M. Yu. Nadinskaya18I. G. Nikitin19N. V. Pogosova20A. I. Tarzimanova21M. Sh. Shamkhalova22I.M. Sechenov First Moscow State Medical UniversitySechenov First Moscow State Medical UniversitySechenov First Moscow State Medical UniversityRussian Gerontology Research and Clinical Centre, Pirogov Russian National Research Medical UniversityRussian Gerontology Research and Clinical Centre, Pirogov Russian National Research Medical UniversityEndocrinology Research CentreEndocrinology Research CentreYevdokimov Moscow State University of Medicine and DentistryBlokhin National Medical Research Center of OncologyStavropol Regional Clinical Center of Specialized Medical CarePirogov Russian National Research Medical UniversityRussian Gerontology Research and Clinical Centre, Pirogov Russian National Research Medical UniversityEndocrinology Research CentreSechenov First Moscow State Medical UniversityEndocrinology Research CentreKuban State Medical UniversityEndocrinology Research CentreEndocrinology Research CentreSechenov First Moscow State Medical UniversityPirogov Russian National Research Medical UniversitNational Medical Research Center of CardiologySechenov First Moscow State Medical UniversityEndocrinology Research CentreAim: present clinical guidelines, aimed at general practitioners, gastroenterologists, cardiologists, endocrinologists, comprise up-to-date methods of diagnosis and treatment of non-alcoholic fatty liver disease.Key points. Nonalcoholic fatty liver disease, the most wide-spread chronic liver disease, is characterized by accumulation of fat by more than 5 % of hepatocytes and presented by two histological forms: steatosis and nonalcoholic steatohepatitis. Clinical guidelines provide current views on pathogenesis of nonalcoholic fatty liver disease as a multisystem disease, methods of invasive and noninvasive diagnosis of steatosis and liver fibrosis, principles of nondrug treatment and pharmacotherapy of nonalcoholic fatty liver disease and associated conditions. Complications of nonalcoholic fatty liver disease include aggravation of cardiometabolic risks, development of hepatocellular cancer, progression of liver fibrosis to cirrhotic stage.Conclusion. Progression of liver disease can be avoided, cardiometabolic risks can be reduced and patients' prognosis — improved by the timely recognition of diagnosis of nonalcoholic fatty liver disease and associated comorbidities and competent multidisciplinary management of these patients.https://www.gastro-j.ru/jour/article/view/777non-alcoholic fatty liver diseasesteatosisliver fibrosissteatohepatitisinsulin resistancecardiovascular diseasesmetabolic disorders
spellingShingle V. T. Ivashkin
M. V. Maevskaya
M. S. Zharkova
Yu. V. Kotovskaya
O. N. Tkacheva
E. A. Troshina
M. V. Shestakova
I. V. Maev
V. V. Breder
N. I. Gheivandova
V. L. Doshchitsin
E. N. Dudinskaya
E. V. Ershova
Kh. B. Kodzoeva
K. A. Komshilova
N. V. Korochanskaya
A. Yu. Mayorov
E. E. Mishina
M. Yu. Nadinskaya
I. G. Nikitin
N. V. Pogosova
A. I. Tarzimanova
M. Sh. Shamkhalova
Clinical Practice Guidelines of the Russian Scientific Liver Society, Russian Gastroenterological Association, Russian Association of Endocrinologists, Russian Association of Gerontologists and Geriatricians and National Society for Preventive Cardiology on Diagnosis and Treatment of Non-Alcoholic Liver Disease
Российский журнал гастроэнтерологии, гепатологии, колопроктологии
non-alcoholic fatty liver disease
steatosis
liver fibrosis
steatohepatitis
insulin resistance
cardiovascular diseases
metabolic disorders
title Clinical Practice Guidelines of the Russian Scientific Liver Society, Russian Gastroenterological Association, Russian Association of Endocrinologists, Russian Association of Gerontologists and Geriatricians and National Society for Preventive Cardiology on Diagnosis and Treatment of Non-Alcoholic Liver Disease
title_full Clinical Practice Guidelines of the Russian Scientific Liver Society, Russian Gastroenterological Association, Russian Association of Endocrinologists, Russian Association of Gerontologists and Geriatricians and National Society for Preventive Cardiology on Diagnosis and Treatment of Non-Alcoholic Liver Disease
title_fullStr Clinical Practice Guidelines of the Russian Scientific Liver Society, Russian Gastroenterological Association, Russian Association of Endocrinologists, Russian Association of Gerontologists and Geriatricians and National Society for Preventive Cardiology on Diagnosis and Treatment of Non-Alcoholic Liver Disease
title_full_unstemmed Clinical Practice Guidelines of the Russian Scientific Liver Society, Russian Gastroenterological Association, Russian Association of Endocrinologists, Russian Association of Gerontologists and Geriatricians and National Society for Preventive Cardiology on Diagnosis and Treatment of Non-Alcoholic Liver Disease
title_short Clinical Practice Guidelines of the Russian Scientific Liver Society, Russian Gastroenterological Association, Russian Association of Endocrinologists, Russian Association of Gerontologists and Geriatricians and National Society for Preventive Cardiology on Diagnosis and Treatment of Non-Alcoholic Liver Disease
title_sort clinical practice guidelines of the russian scientific liver society russian gastroenterological association russian association of endocrinologists russian association of gerontologists and geriatricians and national society for preventive cardiology on diagnosis and treatment of non alcoholic liver disease
topic non-alcoholic fatty liver disease
steatosis
liver fibrosis
steatohepatitis
insulin resistance
cardiovascular diseases
metabolic disorders
url https://www.gastro-j.ru/jour/article/view/777
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