Growth performance and immune response of broilers during active Eimeria infection are modified by dietary inclusion of canola meal or corn-DDGS in reduced-protein corn-soybean meal diets
The objective of this experiment was to study the effects of partial replacement of soybean meal (SBM) with canola meal (CM) or corn-distillers' dried grains with solubles (cDDGS) in reduced-protein (RP) diets for Eimeria-infected broilers. A total of 1120 broiler chicks were distributed in a 4...
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KeAi Communications Co., Ltd.
2024-12-01
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| Online Access: | http://www.sciencedirect.com/science/article/pii/S2405654524001033 |
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| author | Revathi Shanmugasundaram Adeleye M. Ajao Shahna Fathima Adelumola Oladeinde Ramesh K. Selvaraj Todd J. Applegate Oluyinka A. Olukosi |
| author_facet | Revathi Shanmugasundaram Adeleye M. Ajao Shahna Fathima Adelumola Oladeinde Ramesh K. Selvaraj Todd J. Applegate Oluyinka A. Olukosi |
| author_sort | Revathi Shanmugasundaram |
| collection | DOAJ |
| description | The objective of this experiment was to study the effects of partial replacement of soybean meal (SBM) with canola meal (CM) or corn-distillers' dried grains with solubles (cDDGS) in reduced-protein (RP) diets for Eimeria-infected broilers. A total of 1120 broiler chicks were distributed in a 4 × 2 (4 diets × with or without infection) factorial arrangement with 7 replicates per treatment and 20 birds per replicate. The 4 diets, fed between d 7 and 42, were (i) a standard diet with crude protein at 200 g/kg (SP); (ii) a RP (crude protein at 160 g/kg) corn-SBM diet (RP-SBM); (iii) a RP diet in which 80 g/kg CM replaced 60 g/kg SBM (RP-CM); and (iv) a RP diet in which 100 g/kg cDDGS replaced 50 g/kg SBM (RP-cDDGS). On d 15, birds were infected with mixed Eimeria (+E) oocysts. Birds and feed were weighed at intervals for growth performance, and samples for immunology responses were collected on d 21. The results showed as follows: 1) during the acute infection phase, diet × Eimeria infection was shown by the diets having no effect in the uninfected group. In contrast, the RP-SBM diet tended to produce higher (P < 0.10) weight gain among the infected birds. The d 42 body weight was greater (P = 0.001) for the uninfected birds. 2) There was a significant diet × Eimeria infection on bile anti-Eimeria immunoglobulin A (IgA) concentrations (P = 0.015), splenocyte proliferation, macrophage nitric oxide (NO) production (P < 0.001), and cecal tonsil interleukin (IL)-17 mRNA amounts (P < 0.001). Most of these responses were not influenced by the diets in the uninfected birds. However, among the infected birds, birds fed RP-SBM had higher (P < 0.05) bile IgA than those fed SP or RP-cDDGS. For the spleen, the interaction was that birds fed RP-SBM or RP-cDDGS diets had the highest or lowest NO production, respectively, and birds that received RP-SBM had greater (P < 0.05) splenic CD8+:CD4+ cell ratio than other diets. In conclusion, partial replacement of SBM with CM or cDDGS had only a marginal effect on d 42 body weight and FCR of the broiler chickens receiving the RP diets. In contrast, these had a negative impact on the immune responses of the broiler chickens. |
| format | Article |
| id | doaj-art-dd85ce3e622d4ba68446fc463788550d |
| institution | DOAJ |
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| spelling | doaj-art-dd85ce3e622d4ba68446fc463788550d2025-08-20T02:51:19ZengKeAi Communications Co., Ltd.Animal Nutrition2405-65452024-12-011944245210.1016/j.aninu.2024.05.007Growth performance and immune response of broilers during active Eimeria infection are modified by dietary inclusion of canola meal or corn-DDGS in reduced-protein corn-soybean meal dietsRevathi Shanmugasundaram0Adeleye M. Ajao1Shahna Fathima2Adelumola Oladeinde3Ramesh K. Selvaraj4Todd J. Applegate5Oluyinka A. Olukosi6Toxicology and Mycotoxin Research Unit, USDA-ARS, Athens, GA, USA; Corresponding authors.Department of Poultry Science, University of Georgia, Athens, GA, USADepartment of Poultry Science, University of Georgia, Athens, GA, USAEgg and Poultry Production Safety Research Unit, USDA-ARS, Athens, GA, USADepartment of Poultry Science, University of Georgia, Athens, GA, USADepartment of Poultry Science, University of Georgia, Athens, GA, USADepartment of Poultry Science, University of Georgia, Athens, GA, USA; Corresponding authors.The objective of this experiment was to study the effects of partial replacement of soybean meal (SBM) with canola meal (CM) or corn-distillers' dried grains with solubles (cDDGS) in reduced-protein (RP) diets for Eimeria-infected broilers. A total of 1120 broiler chicks were distributed in a 4 × 2 (4 diets × with or without infection) factorial arrangement with 7 replicates per treatment and 20 birds per replicate. The 4 diets, fed between d 7 and 42, were (i) a standard diet with crude protein at 200 g/kg (SP); (ii) a RP (crude protein at 160 g/kg) corn-SBM diet (RP-SBM); (iii) a RP diet in which 80 g/kg CM replaced 60 g/kg SBM (RP-CM); and (iv) a RP diet in which 100 g/kg cDDGS replaced 50 g/kg SBM (RP-cDDGS). On d 15, birds were infected with mixed Eimeria (+E) oocysts. Birds and feed were weighed at intervals for growth performance, and samples for immunology responses were collected on d 21. The results showed as follows: 1) during the acute infection phase, diet × Eimeria infection was shown by the diets having no effect in the uninfected group. In contrast, the RP-SBM diet tended to produce higher (P < 0.10) weight gain among the infected birds. The d 42 body weight was greater (P = 0.001) for the uninfected birds. 2) There was a significant diet × Eimeria infection on bile anti-Eimeria immunoglobulin A (IgA) concentrations (P = 0.015), splenocyte proliferation, macrophage nitric oxide (NO) production (P < 0.001), and cecal tonsil interleukin (IL)-17 mRNA amounts (P < 0.001). Most of these responses were not influenced by the diets in the uninfected birds. However, among the infected birds, birds fed RP-SBM had higher (P < 0.05) bile IgA than those fed SP or RP-cDDGS. For the spleen, the interaction was that birds fed RP-SBM or RP-cDDGS diets had the highest or lowest NO production, respectively, and birds that received RP-SBM had greater (P < 0.05) splenic CD8+:CD4+ cell ratio than other diets. In conclusion, partial replacement of SBM with CM or cDDGS had only a marginal effect on d 42 body weight and FCR of the broiler chickens receiving the RP diets. In contrast, these had a negative impact on the immune responses of the broiler chickens.http://www.sciencedirect.com/science/article/pii/S2405654524001033Reduced-protein dietEimeriaBroiler chickenGrowthImmune response |
| spellingShingle | Revathi Shanmugasundaram Adeleye M. Ajao Shahna Fathima Adelumola Oladeinde Ramesh K. Selvaraj Todd J. Applegate Oluyinka A. Olukosi Growth performance and immune response of broilers during active Eimeria infection are modified by dietary inclusion of canola meal or corn-DDGS in reduced-protein corn-soybean meal diets Animal Nutrition Reduced-protein diet Eimeria Broiler chicken Growth Immune response |
| title | Growth performance and immune response of broilers during active Eimeria infection are modified by dietary inclusion of canola meal or corn-DDGS in reduced-protein corn-soybean meal diets |
| title_full | Growth performance and immune response of broilers during active Eimeria infection are modified by dietary inclusion of canola meal or corn-DDGS in reduced-protein corn-soybean meal diets |
| title_fullStr | Growth performance and immune response of broilers during active Eimeria infection are modified by dietary inclusion of canola meal or corn-DDGS in reduced-protein corn-soybean meal diets |
| title_full_unstemmed | Growth performance and immune response of broilers during active Eimeria infection are modified by dietary inclusion of canola meal or corn-DDGS in reduced-protein corn-soybean meal diets |
| title_short | Growth performance and immune response of broilers during active Eimeria infection are modified by dietary inclusion of canola meal or corn-DDGS in reduced-protein corn-soybean meal diets |
| title_sort | growth performance and immune response of broilers during active eimeria infection are modified by dietary inclusion of canola meal or corn ddgs in reduced protein corn soybean meal diets |
| topic | Reduced-protein diet Eimeria Broiler chicken Growth Immune response |
| url | http://www.sciencedirect.com/science/article/pii/S2405654524001033 |
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