A Case of Atorvastatin-Associated Necrotizing Autoimmune Myopathy, Mimicking Idiopathic Polymyositis
Statin-induced necrotizing autoimmune myopathy (SINAM) is a rare side effect of statin use which manifests as progressive muscle weakness. Because statins are a widely prescribed medication for coronary artery disease, hyperlipidemia, and many other diseases, many patients are at risk of developing...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Rheumatology |
| Online Access: | http://dx.doi.org/10.1155/2018/5931046 |
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| _version_ | 1850166153164357632 |
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| author | Ayushi Dixit Adriana Abrudescu |
| author_facet | Ayushi Dixit Adriana Abrudescu |
| author_sort | Ayushi Dixit |
| collection | DOAJ |
| description | Statin-induced necrotizing autoimmune myopathy (SINAM) is a rare side effect of statin use which manifests as progressive muscle weakness. Because statins are a widely prescribed medication for coronary artery disease, hyperlipidemia, and many other diseases, many patients are at risk of developing SINAM or one of the many other statin-induced myopathies. Due to identification of an antibody specific to this disease, we were able to diagnose SINAM in a patient whose symptoms had progressed to the extent that they were debilitating. Our case describes SINAM in a patient undergoing treatment with a statin for an extended period of time, diagnosis of the disease process, treatment, and resolution of symptoms. |
| format | Article |
| id | doaj-art-dd820dbbe406432380c0d95a44b93cb5 |
| institution | OA Journals |
| issn | 2090-6889 2090-6897 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Rheumatology |
| spelling | doaj-art-dd820dbbe406432380c0d95a44b93cb52025-08-20T02:21:33ZengWileyCase Reports in Rheumatology2090-68892090-68972018-01-01201810.1155/2018/59310465931046A Case of Atorvastatin-Associated Necrotizing Autoimmune Myopathy, Mimicking Idiopathic PolymyositisAyushi Dixit0Adriana Abrudescu1Icahn School of Medicine at Mount Sinai-Queens Hospital Center, Queens, NY, USAIcahn School of Medicine at Mount Sinai-Queens Hospital Center, Queens, NY, USAStatin-induced necrotizing autoimmune myopathy (SINAM) is a rare side effect of statin use which manifests as progressive muscle weakness. Because statins are a widely prescribed medication for coronary artery disease, hyperlipidemia, and many other diseases, many patients are at risk of developing SINAM or one of the many other statin-induced myopathies. Due to identification of an antibody specific to this disease, we were able to diagnose SINAM in a patient whose symptoms had progressed to the extent that they were debilitating. Our case describes SINAM in a patient undergoing treatment with a statin for an extended period of time, diagnosis of the disease process, treatment, and resolution of symptoms.http://dx.doi.org/10.1155/2018/5931046 |
| spellingShingle | Ayushi Dixit Adriana Abrudescu A Case of Atorvastatin-Associated Necrotizing Autoimmune Myopathy, Mimicking Idiopathic Polymyositis Case Reports in Rheumatology |
| title | A Case of Atorvastatin-Associated Necrotizing Autoimmune Myopathy, Mimicking Idiopathic Polymyositis |
| title_full | A Case of Atorvastatin-Associated Necrotizing Autoimmune Myopathy, Mimicking Idiopathic Polymyositis |
| title_fullStr | A Case of Atorvastatin-Associated Necrotizing Autoimmune Myopathy, Mimicking Idiopathic Polymyositis |
| title_full_unstemmed | A Case of Atorvastatin-Associated Necrotizing Autoimmune Myopathy, Mimicking Idiopathic Polymyositis |
| title_short | A Case of Atorvastatin-Associated Necrotizing Autoimmune Myopathy, Mimicking Idiopathic Polymyositis |
| title_sort | case of atorvastatin associated necrotizing autoimmune myopathy mimicking idiopathic polymyositis |
| url | http://dx.doi.org/10.1155/2018/5931046 |
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