Sarcopenia Is Associated with High Pulse Pressure in Older Women
Introduction. Sarcopenia is a geriatric syndrome associated with impairment of muscle function, metabolism, and cognition in older women. Recent studies have shown a relationship between changes in muscle mass and the cardiovascular system. However, this relationship has not been fully elucidated. M...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Journal of Aging Research |
| Online Access: | http://dx.doi.org/10.1155/2015/109824 |
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| author | Hélio José Coelho Júnior Samuel da Silva Aguiar Ivan de Oliveira Gonçalves Ricardo Aurélio Carvalho Sampaio Marco Carlos Uchida Milton Rocha Moraes Ricardo Yukio Asano |
| author_facet | Hélio José Coelho Júnior Samuel da Silva Aguiar Ivan de Oliveira Gonçalves Ricardo Aurélio Carvalho Sampaio Marco Carlos Uchida Milton Rocha Moraes Ricardo Yukio Asano |
| author_sort | Hélio José Coelho Júnior |
| collection | DOAJ |
| description | Introduction. Sarcopenia is a geriatric syndrome associated with impairment of muscle function, metabolism, and cognition in older women. Recent studies have shown a relationship between changes in muscle mass and the cardiovascular system. However, this relationship has not been fully elucidated. Methods. One hundred and thirty community-dwelling Brazilian older women (65.4 ± 6.3 years) were recruited to participate in this study. Data on body composition (via bioelectrical impedance measurements), cardiovascular parameters (using an automatic and noninvasive monitor), and muscle function (using a 3-meter gait speed test) were measured. Results. Sarcopenic older women (n=43) presented higher levels of pulse pressure (PP) (60.3 ± 2.6 mmHg) and lower muscle function (0.5 ± 0.0 m/s) compared with nonsarcopenic subjects (n=87) (53.7 ± 1.5 mmHg; 0.9 ± 0.0 m/s) (P<0.05). Linear regression analysis demonstrated a significantly negative association between skeletal muscle index (SMI) and PP levels (β=−226, P<0.05). Furthermore, sarcopenic older women showed a 3.1-fold increased risk of having higher PP levels compared with nonsarcopenic women (IC = 1.323–7.506) (P<0.05). Conclusion. Sarcopenic older women showed lower muscle function and higher cardiovascular risk due to increased PP levels compared with nonsarcopenic subjects. |
| format | Article |
| id | doaj-art-dd816f8227b44605aaec25edcf9c2d98 |
| institution | Kabale University |
| issn | 2090-2204 2090-2212 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Aging Research |
| spelling | doaj-art-dd816f8227b44605aaec25edcf9c2d982025-02-03T01:20:45ZengWileyJournal of Aging Research2090-22042090-22122015-01-01201510.1155/2015/109824109824Sarcopenia Is Associated with High Pulse Pressure in Older WomenHélio José Coelho Júnior0Samuel da Silva Aguiar1Ivan de Oliveira Gonçalves2Ricardo Aurélio Carvalho Sampaio3Marco Carlos Uchida4Milton Rocha Moraes5Ricardo Yukio Asano6School of Physical Education, State University of Campinas, 130883851 Campinas, BrazilCenter of Health Sciences, University of Mogi das Cruzes, 08770-490 Mogi das Cruzes, BrazilCommunity Center for Older People of Poá, Poá, BrazilSchool of Physical Education, State University of Campinas, 130883851 Campinas, BrazilSchool of Physical Education, State University of Campinas, 130883851 Campinas, BrazilGraduate Program on Physical Education, Catholic University of Brasilia, 71966-700 Brasilia, BrazilCenter of Health Sciences, University of Mogi das Cruzes, 08770-490 Mogi das Cruzes, BrazilIntroduction. Sarcopenia is a geriatric syndrome associated with impairment of muscle function, metabolism, and cognition in older women. Recent studies have shown a relationship between changes in muscle mass and the cardiovascular system. However, this relationship has not been fully elucidated. Methods. One hundred and thirty community-dwelling Brazilian older women (65.4 ± 6.3 years) were recruited to participate in this study. Data on body composition (via bioelectrical impedance measurements), cardiovascular parameters (using an automatic and noninvasive monitor), and muscle function (using a 3-meter gait speed test) were measured. Results. Sarcopenic older women (n=43) presented higher levels of pulse pressure (PP) (60.3 ± 2.6 mmHg) and lower muscle function (0.5 ± 0.0 m/s) compared with nonsarcopenic subjects (n=87) (53.7 ± 1.5 mmHg; 0.9 ± 0.0 m/s) (P<0.05). Linear regression analysis demonstrated a significantly negative association between skeletal muscle index (SMI) and PP levels (β=−226, P<0.05). Furthermore, sarcopenic older women showed a 3.1-fold increased risk of having higher PP levels compared with nonsarcopenic women (IC = 1.323–7.506) (P<0.05). Conclusion. Sarcopenic older women showed lower muscle function and higher cardiovascular risk due to increased PP levels compared with nonsarcopenic subjects.http://dx.doi.org/10.1155/2015/109824 |
| spellingShingle | Hélio José Coelho Júnior Samuel da Silva Aguiar Ivan de Oliveira Gonçalves Ricardo Aurélio Carvalho Sampaio Marco Carlos Uchida Milton Rocha Moraes Ricardo Yukio Asano Sarcopenia Is Associated with High Pulse Pressure in Older Women Journal of Aging Research |
| title | Sarcopenia Is Associated with High Pulse Pressure in Older Women |
| title_full | Sarcopenia Is Associated with High Pulse Pressure in Older Women |
| title_fullStr | Sarcopenia Is Associated with High Pulse Pressure in Older Women |
| title_full_unstemmed | Sarcopenia Is Associated with High Pulse Pressure in Older Women |
| title_short | Sarcopenia Is Associated with High Pulse Pressure in Older Women |
| title_sort | sarcopenia is associated with high pulse pressure in older women |
| url | http://dx.doi.org/10.1155/2015/109824 |
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