Infected congenital pericardial cyst with mass effect on adjacent structures, a rare presentation in an infant in LMIC setting: a case report and review of literature

Abstract Background Giant pericardial cysts are rare mediastinal lesions that can lead to significant morbidity if complicated by infection, compression of adjacent structures, or secondary complications such as right-sided heart failure. This case report highlights the diagnostic and therapeutic ch...

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Main Authors: Ashagre Gebremichael Ganta, Wintana Tesfaye Desta
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Pediatrics
Subjects:
Online Access:https://doi.org/10.1186/s12887-025-05606-8
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author Ashagre Gebremichael Ganta
Wintana Tesfaye Desta
author_facet Ashagre Gebremichael Ganta
Wintana Tesfaye Desta
author_sort Ashagre Gebremichael Ganta
collection DOAJ
description Abstract Background Giant pericardial cysts are rare mediastinal lesions that can lead to significant morbidity if complicated by infection, compression of adjacent structures, or secondary complications such as right-sided heart failure. This case report highlights the diagnostic and therapeutic challenges of managing an infected giant pericardial cyst in a resource-limited setting in Africa. Case presentation A 2 months old infant presented with symptoms of fast breathing, dyspnea, fever, and signs of right-sided heart failure, including peripheral edema and ascites. Imaging studies, including chest X-ray and computed tomography (CT), revealed a large cystic mass in the pericardial region compressing the right heart chambers. Emergency Surgical excision was performed, and histopathological analysis confirmed the diagnosis of an infected pericardial cyst. Postoperatively, the patient recovered well, with resolution of symptoms, including signs of right-sided heart failure, and no recurrence at follow-up. Conclusion This case underscores the importance of considering pericardial cysts in the differential diagnosis of mediastinal masses, particularly in the presence of infectious symptoms or cardiac compression leading to right-sided heart failure. It also demonstrates the feasibility of successful management through timely surgical intervention, even in resource-limited settings. This report contributes to the sparse literature on infected pericardial cysts and provides valuable insights into their management in low-resource environments. Clinical trial number Not applicable.
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spelling doaj-art-dd802d3701c0437ca22c13dd8615d45b2025-08-20T01:54:20ZengBMCBMC Pediatrics1471-24312025-03-012511510.1186/s12887-025-05606-8Infected congenital pericardial cyst with mass effect on adjacent structures, a rare presentation in an infant in LMIC setting: a case report and review of literatureAshagre Gebremichael Ganta0Wintana Tesfaye Desta1Department of Surgery, Hawassa University HospitalDepartment of PediatricsAbstract Background Giant pericardial cysts are rare mediastinal lesions that can lead to significant morbidity if complicated by infection, compression of adjacent structures, or secondary complications such as right-sided heart failure. This case report highlights the diagnostic and therapeutic challenges of managing an infected giant pericardial cyst in a resource-limited setting in Africa. Case presentation A 2 months old infant presented with symptoms of fast breathing, dyspnea, fever, and signs of right-sided heart failure, including peripheral edema and ascites. Imaging studies, including chest X-ray and computed tomography (CT), revealed a large cystic mass in the pericardial region compressing the right heart chambers. Emergency Surgical excision was performed, and histopathological analysis confirmed the diagnosis of an infected pericardial cyst. Postoperatively, the patient recovered well, with resolution of symptoms, including signs of right-sided heart failure, and no recurrence at follow-up. Conclusion This case underscores the importance of considering pericardial cysts in the differential diagnosis of mediastinal masses, particularly in the presence of infectious symptoms or cardiac compression leading to right-sided heart failure. It also demonstrates the feasibility of successful management through timely surgical intervention, even in resource-limited settings. This report contributes to the sparse literature on infected pericardial cysts and provides valuable insights into their management in low-resource environments. Clinical trial number Not applicable.https://doi.org/10.1186/s12887-025-05606-8Pericardial cystInfectionHeart failureInfantsCase report
spellingShingle Ashagre Gebremichael Ganta
Wintana Tesfaye Desta
Infected congenital pericardial cyst with mass effect on adjacent structures, a rare presentation in an infant in LMIC setting: a case report and review of literature
BMC Pediatrics
Pericardial cyst
Infection
Heart failure
Infants
Case report
title Infected congenital pericardial cyst with mass effect on adjacent structures, a rare presentation in an infant in LMIC setting: a case report and review of literature
title_full Infected congenital pericardial cyst with mass effect on adjacent structures, a rare presentation in an infant in LMIC setting: a case report and review of literature
title_fullStr Infected congenital pericardial cyst with mass effect on adjacent structures, a rare presentation in an infant in LMIC setting: a case report and review of literature
title_full_unstemmed Infected congenital pericardial cyst with mass effect on adjacent structures, a rare presentation in an infant in LMIC setting: a case report and review of literature
title_short Infected congenital pericardial cyst with mass effect on adjacent structures, a rare presentation in an infant in LMIC setting: a case report and review of literature
title_sort infected congenital pericardial cyst with mass effect on adjacent structures a rare presentation in an infant in lmic setting a case report and review of literature
topic Pericardial cyst
Infection
Heart failure
Infants
Case report
url https://doi.org/10.1186/s12887-025-05606-8
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