A 9month-old-boy with atypical hemophagocytic lymphohistiocytosis
Hemophagocytic lymphohistiocytosis is a life-threatening hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and histiocytes. Often, Hemophagocytic lymphohistiocytosis is an acquired syndrome. We report a case of a 9 month-old-boy presented with hepatosplenomegaly, severe...
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| Format: | Article |
| Language: | English |
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PAGEPress Publications
2017-10-01
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| Series: | Mediterranean Journal of Hematology and Infectious Diseases |
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| Online Access: | http://www.mjhid.org/index.php/mjhid/article/view/3046 |
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| author | Monia Ouederni MONIA BEN KHALED Samia Rekaya Ilhem Ben Fraj Fethi Mellouli Mohamed Bejaoui |
| author_facet | Monia Ouederni MONIA BEN KHALED Samia Rekaya Ilhem Ben Fraj Fethi Mellouli Mohamed Bejaoui |
| author_sort | Monia Ouederni |
| collection | DOAJ |
| description | Hemophagocytic lymphohistiocytosis is a life-threatening hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and histiocytes. Often, Hemophagocytic lymphohistiocytosis is an acquired syndrome. We report a case of a 9 month-old-boy presented with hepatosplenomegaly, severe anemia requiring repeated transfusions, thrombocytopenia, hypertriglyceridemia and very high hyperferritinemia. These clinical features of Hemophagocytic lymphohistiocytosis prompted a wide infectious and auto-immune request to be performed. After a wide diagnostic workup, he was referred to the immune hematologic unit, for hemophagocytic lymphohistiocytosis suspicion with unknown cause. |
| format | Article |
| id | doaj-art-dd7cfcb6b74841f982a35d6fb5fcc85f |
| institution | Kabale University |
| issn | 2035-3006 |
| language | English |
| publishDate | 2017-10-01 |
| publisher | PAGEPress Publications |
| record_format | Article |
| series | Mediterranean Journal of Hematology and Infectious Diseases |
| spelling | doaj-art-dd7cfcb6b74841f982a35d6fb5fcc85f2025-01-02T11:15:07ZengPAGEPress PublicationsMediterranean Journal of Hematology and Infectious Diseases2035-30062017-10-0191e2017057e201705710.4084/mjhid.2017.571712A 9month-old-boy with atypical hemophagocytic lymphohistiocytosisMonia Ouederni0MONIA BEN KHALED1Samia Rekaya2Ilhem Ben Fraj3Fethi Mellouli4Mohamed Bejaoui5Faculty of Medicine, University of Tunis El Manar, Tunis, Tunisia. Bone marrow transplantation center TunisFaculty of Medicine, University of Tunis El Manar Bone marrow transplantation center TunisFaculty of Medicine, University of Tunis El Manar Bone marrow transplantation center TunisFaculty of Medicine, University of Tunis El Manar Bone marrow transplantation center TunisFaculty of Medicine, University of Tunis El Manar Bone marrow transplantation center TunisFaculty of Medicine, University of Tunis El Manar Bone marrow transplantation center TunisHemophagocytic lymphohistiocytosis is a life-threatening hyperinflammation caused by uncontrolled proliferation of activated lymphocytes and histiocytes. Often, Hemophagocytic lymphohistiocytosis is an acquired syndrome. We report a case of a 9 month-old-boy presented with hepatosplenomegaly, severe anemia requiring repeated transfusions, thrombocytopenia, hypertriglyceridemia and very high hyperferritinemia. These clinical features of Hemophagocytic lymphohistiocytosis prompted a wide infectious and auto-immune request to be performed. After a wide diagnostic workup, he was referred to the immune hematologic unit, for hemophagocytic lymphohistiocytosis suspicion with unknown cause.http://www.mjhid.org/index.php/mjhid/article/view/3046Anemia, Neutropenia, , thrombocytopenia, hyperfeeeritinemia, Haemophagocytic lymphohistiocytosis |
| spellingShingle | Monia Ouederni MONIA BEN KHALED Samia Rekaya Ilhem Ben Fraj Fethi Mellouli Mohamed Bejaoui A 9month-old-boy with atypical hemophagocytic lymphohistiocytosis Mediterranean Journal of Hematology and Infectious Diseases Anemia, Neutropenia, , thrombocytopenia, hyperfeeeritinemia, Haemophagocytic lymphohistiocytosis |
| title | A 9month-old-boy with atypical hemophagocytic lymphohistiocytosis |
| title_full | A 9month-old-boy with atypical hemophagocytic lymphohistiocytosis |
| title_fullStr | A 9month-old-boy with atypical hemophagocytic lymphohistiocytosis |
| title_full_unstemmed | A 9month-old-boy with atypical hemophagocytic lymphohistiocytosis |
| title_short | A 9month-old-boy with atypical hemophagocytic lymphohistiocytosis |
| title_sort | 9month old boy with atypical hemophagocytic lymphohistiocytosis |
| topic | Anemia, Neutropenia, , thrombocytopenia, hyperfeeeritinemia, Haemophagocytic lymphohistiocytosis |
| url | http://www.mjhid.org/index.php/mjhid/article/view/3046 |
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