Risk factors for infection development after transrectal prostate biopsy and the role of resistant bacteria in colonic flora
Introduction: In this study, we aimed to identify risk factors for the development of infectious complications after prostate biopsy and to investigate the role of intestinal colonization of bacteria that are resistant to prophylactic antibiotics. Methodology: A total of 168 patients who had unde...
Saved in:
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
The Journal of Infection in Developing Countries
2017-02-01
|
| Series: | Journal of Infection in Developing Countries |
| Subjects: | |
| Online Access: | https://jidc.org/index.php/journal/article/view/7067 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850193890955493376 |
|---|---|
| author | Emine Dilek Eruz Aysun Yalci Eriz Ozden Halide Aslaner Suna Ogucu-Durgun Deniz Derya Koseoglu-Taymur Kemal Osman Memikoglu Hakan Erdem Halil Kurt |
| author_facet | Emine Dilek Eruz Aysun Yalci Eriz Ozden Halide Aslaner Suna Ogucu-Durgun Deniz Derya Koseoglu-Taymur Kemal Osman Memikoglu Hakan Erdem Halil Kurt |
| author_sort | Emine Dilek Eruz |
| collection | DOAJ |
| description |
Introduction: In this study, we aimed to identify risk factors for the development of infectious complications after prostate biopsy and to investigate the role of intestinal colonization of bacteria that are resistant to prophylactic antibiotics.
Methodology: A total of 168 patients who had undergone transrectal prostate biopsy (TRPB) under ciprofloxacin and gentamycin prophylaxis were included in the study. Stool cultures and subsequent antibiotic susceptibility testing were performed in all patients before the start of antibiotic prophylaxis.
Results: Of the 168 patients, 17 (10.1%) developed urinary tract infection (UTI), while 6 (3.57%) developed sepsis within seven days after biopsy. Ciprofloxacin-resistant bacterial colonization was detected in 81 (48.2%) of the patients. None of the patients with ciprofloxacin-sensitive bacteria in intestinal flora developed a UTI. The colonization of intestinal ciprofloxacin-resistant bacteria increased UTI risk significantly after TRPB (p < 0.0001). Urolithiasis history, presence of permanent urinary catheterization, hospitalization history for more than 48 hours in the last year, and recent antibiotic usage significantly increased UTI risk after TRPB.
Conclusions: Development of an infection was more frequent in patients with resistant bacterial colonization. We hope to guide more comprehensive studies designed to find a standard prophylactic regimen for TRPB that can be used all over the world.
|
| format | Article |
| id | doaj-art-dd7761e76bcb4047b02a738976fab71f |
| institution | OA Journals |
| issn | 1972-2680 |
| language | English |
| publishDate | 2017-02-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-dd7761e76bcb4047b02a738976fab71f2025-08-20T02:14:07ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802017-02-01110210.3855/jidc.7067Risk factors for infection development after transrectal prostate biopsy and the role of resistant bacteria in colonic floraEmine Dilek Eruz0Aysun Yalci1Eriz Ozden2Halide Aslaner3Suna Ogucu-Durgun4Deniz Derya Koseoglu-Taymur5Kemal Osman Memikoglu6Hakan Erdem7Halil Kurt8Faculty of Medicine, Ankara University, Ankara, TurkeyFaculty of Medicine, Ankara University, Ankara, TurkeyFaculty of Medicine, Ankara University, Ankara, TurkeyAnkara Numune Teaching and Research Hospital, Ankara, TurkeyIzmir Atatürk Teaching and Research Hospital, Izmir, TurkeyBursa Cekirge Public Hospital, Bursa, TurkeyFaculty of Medicine, Ankara University, Ankara, TurkeyKasimpasa Military Hospital, Istanbul, TurkeyTOBB University, Ankara, Turkey Introduction: In this study, we aimed to identify risk factors for the development of infectious complications after prostate biopsy and to investigate the role of intestinal colonization of bacteria that are resistant to prophylactic antibiotics. Methodology: A total of 168 patients who had undergone transrectal prostate biopsy (TRPB) under ciprofloxacin and gentamycin prophylaxis were included in the study. Stool cultures and subsequent antibiotic susceptibility testing were performed in all patients before the start of antibiotic prophylaxis. Results: Of the 168 patients, 17 (10.1%) developed urinary tract infection (UTI), while 6 (3.57%) developed sepsis within seven days after biopsy. Ciprofloxacin-resistant bacterial colonization was detected in 81 (48.2%) of the patients. None of the patients with ciprofloxacin-sensitive bacteria in intestinal flora developed a UTI. The colonization of intestinal ciprofloxacin-resistant bacteria increased UTI risk significantly after TRPB (p < 0.0001). Urolithiasis history, presence of permanent urinary catheterization, hospitalization history for more than 48 hours in the last year, and recent antibiotic usage significantly increased UTI risk after TRPB. Conclusions: Development of an infection was more frequent in patients with resistant bacterial colonization. We hope to guide more comprehensive studies designed to find a standard prophylactic regimen for TRPB that can be used all over the world. https://jidc.org/index.php/journal/article/view/7067Prostate biopsyurinary tract infectionintestinal floraquinolone resistanceprophylaxis |
| spellingShingle | Emine Dilek Eruz Aysun Yalci Eriz Ozden Halide Aslaner Suna Ogucu-Durgun Deniz Derya Koseoglu-Taymur Kemal Osman Memikoglu Hakan Erdem Halil Kurt Risk factors for infection development after transrectal prostate biopsy and the role of resistant bacteria in colonic flora Journal of Infection in Developing Countries Prostate biopsy urinary tract infection intestinal flora quinolone resistance prophylaxis |
| title | Risk factors for infection development after transrectal prostate biopsy and the role of resistant bacteria in colonic flora |
| title_full | Risk factors for infection development after transrectal prostate biopsy and the role of resistant bacteria in colonic flora |
| title_fullStr | Risk factors for infection development after transrectal prostate biopsy and the role of resistant bacteria in colonic flora |
| title_full_unstemmed | Risk factors for infection development after transrectal prostate biopsy and the role of resistant bacteria in colonic flora |
| title_short | Risk factors for infection development after transrectal prostate biopsy and the role of resistant bacteria in colonic flora |
| title_sort | risk factors for infection development after transrectal prostate biopsy and the role of resistant bacteria in colonic flora |
| topic | Prostate biopsy urinary tract infection intestinal flora quinolone resistance prophylaxis |
| url | https://jidc.org/index.php/journal/article/view/7067 |
| work_keys_str_mv | AT eminedilekeruz riskfactorsforinfectiondevelopmentaftertransrectalprostatebiopsyandtheroleofresistantbacteriaincolonicflora AT aysunyalci riskfactorsforinfectiondevelopmentaftertransrectalprostatebiopsyandtheroleofresistantbacteriaincolonicflora AT erizozden riskfactorsforinfectiondevelopmentaftertransrectalprostatebiopsyandtheroleofresistantbacteriaincolonicflora AT halideaslaner riskfactorsforinfectiondevelopmentaftertransrectalprostatebiopsyandtheroleofresistantbacteriaincolonicflora AT sunaogucudurgun riskfactorsforinfectiondevelopmentaftertransrectalprostatebiopsyandtheroleofresistantbacteriaincolonicflora AT denizderyakoseoglutaymur riskfactorsforinfectiondevelopmentaftertransrectalprostatebiopsyandtheroleofresistantbacteriaincolonicflora AT kemalosmanmemikoglu riskfactorsforinfectiondevelopmentaftertransrectalprostatebiopsyandtheroleofresistantbacteriaincolonicflora AT hakanerdem riskfactorsforinfectiondevelopmentaftertransrectalprostatebiopsyandtheroleofresistantbacteriaincolonicflora AT halilkurt riskfactorsforinfectiondevelopmentaftertransrectalprostatebiopsyandtheroleofresistantbacteriaincolonicflora |