Roles of Tick Symbiotic Microorganisms in Pathogen Transmission

Ticks have garnered significant research interest owing to their ability to vector pathogens into humans and animals. The intricate symbiotic associations between ticks and tick microbiota substantially influence developmental processes, reproductive success, and potential to serve as vectors for ti...

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Main Authors: Xiongxiong Chang, Xiang Li, Yaping Pei, Enjie Deng, Shubiao Wu, Jiafu Jiang, Lin Jin
Format: Article
Language:English
Published: Compuscript Ltd 2025-06-01
Series:Zoonoses
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2024-0067
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author Xiongxiong Chang
Xiang Li
Yaping Pei
Enjie Deng
Shubiao Wu
Jiafu Jiang
Lin Jin
author_facet Xiongxiong Chang
Xiang Li
Yaping Pei
Enjie Deng
Shubiao Wu
Jiafu Jiang
Lin Jin
author_sort Xiongxiong Chang
collection DOAJ
description Ticks have garnered significant research interest owing to their ability to vector pathogens into humans and animals. The intricate symbiotic associations between ticks and tick microbiota substantially influence developmental processes, reproductive success, and potential to serve as vectors for tick-transmitted diseases. This paper reviews the epidemiology of diseases transmitted by ticks and delves into the composition and function of tick endosymbionts in transmission and infection. This review also highlights the role of tick immunity in maintaining gut homeostasis. Finally, tick symbiont-pathogen interactions and potential strategies for controlling tick-borne diseases by leveraging symbiotic relationships are discussed.
format Article
id doaj-art-dd77160e96af485f8e3d0785dc4b1dd4
institution Kabale University
issn 2737-7466
2737-7474
language English
publishDate 2025-06-01
publisher Compuscript Ltd
record_format Article
series Zoonoses
spelling doaj-art-dd77160e96af485f8e3d0785dc4b1dd42025-08-20T03:58:49ZengCompuscript LtdZoonoses2737-74662737-74742025-06-015197210.15212/ZOONOSES-2024-0067Roles of Tick Symbiotic Microorganisms in Pathogen TransmissionXiongxiong ChangXiang LiYaping PeiEnjie DengShubiao WuJiafu JiangLin JinTicks have garnered significant research interest owing to their ability to vector pathogens into humans and animals. The intricate symbiotic associations between ticks and tick microbiota substantially influence developmental processes, reproductive success, and potential to serve as vectors for tick-transmitted diseases. This paper reviews the epidemiology of diseases transmitted by ticks and delves into the composition and function of tick endosymbionts in transmission and infection. This review also highlights the role of tick immunity in maintaining gut homeostasis. Finally, tick symbiont-pathogen interactions and potential strategies for controlling tick-borne diseases by leveraging symbiotic relationships are discussed.https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2024-0067
spellingShingle Xiongxiong Chang
Xiang Li
Yaping Pei
Enjie Deng
Shubiao Wu
Jiafu Jiang
Lin Jin
Roles of Tick Symbiotic Microorganisms in Pathogen Transmission
Zoonoses
title Roles of Tick Symbiotic Microorganisms in Pathogen Transmission
title_full Roles of Tick Symbiotic Microorganisms in Pathogen Transmission
title_fullStr Roles of Tick Symbiotic Microorganisms in Pathogen Transmission
title_full_unstemmed Roles of Tick Symbiotic Microorganisms in Pathogen Transmission
title_short Roles of Tick Symbiotic Microorganisms in Pathogen Transmission
title_sort roles of tick symbiotic microorganisms in pathogen transmission
url https://www.scienceopen.com/hosted-document?doi=10.15212/ZOONOSES-2024-0067
work_keys_str_mv AT xiongxiongchang rolesofticksymbioticmicroorganismsinpathogentransmission
AT xiangli rolesofticksymbioticmicroorganismsinpathogentransmission
AT yapingpei rolesofticksymbioticmicroorganismsinpathogentransmission
AT enjiedeng rolesofticksymbioticmicroorganismsinpathogentransmission
AT shubiaowu rolesofticksymbioticmicroorganismsinpathogentransmission
AT jiafujiang rolesofticksymbioticmicroorganismsinpathogentransmission
AT linjin rolesofticksymbioticmicroorganismsinpathogentransmission