Development of Monoclonal Antibodies against CMP-N-Acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (ST3Gal-I) Recombinant Protein Expressed in E. coli

Development of Monoclonal Antibodies against CMP-N-Acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 (ST3Gal-I) Recombinant Protein Expressed in E. coli

Aberrant glycosylation is one of the major hallmarks of cancer with altered gene expression signatures of sialyltransferases. ST3Gal-I, a sialyltransferase, is known to play a crucial role in sialylation of T antigen in bladder cancer and it has reported elevated expression in breast carcinogenesis...

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Bibliographic Details
Main Authors: Anuj Kumar Gupta, Parvinder Kaur, Harshada Patil, Pallavi Kadam, Paresh B. Bhanushali, Manoj Chugh
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Biochemistry Research International
Online Access:http://dx.doi.org/10.1155/2015/767204
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