In silico analysis of CSF2RB from cancer genomic databases reveals a heterogeneous role in different breast cancer subtypes

In silico analysis of CSF2RB from cancer genomic databases reveals a heterogeneous role in different breast cancer subtypes

ObjectiveCSF2RB is the common beta chain of the heterodimeric receptors for the cytokines, granulocyte–macrophage colony-stimulating factor (GM-CSF), interleukin 3 (IL-3), and interleukin 5 (IL-5). The activation of these cell surface receptors results in functional responses including cellular prol...

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Bibliographic Details
Main Authors: Raghad Alshelaiel, Abdulmohsen Alkushi, Lolwah Abdullah Alriyees, Abir Abdullah Alamro, Humidah Alanazi, Areej Alhareeri, Bader AlMuzzaini, Mamoon Rashid
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Bioinformatics
Subjects:
cancer
breast cancer
colony-stimulating factor 2 receptor subunit beta
prognosis
cancer genomics
bioinformatics
Online Access:https://www.frontiersin.org/articles/10.3389/fbinf.2025.1606828/full
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