Mechanism of Acetophenone Fumigation to Inhibit Postharvest Botrytis cinerea in Grape

Gray mold is one of the main diseases in postharvest storage of grape. To explore the inhibition mechanism of acetophenone fumigation on Botrytis cinerea. When acetophenone was the lowest fungistatic concentration, the morphology and structure of the hypha of B. cinerea were observed by electron mic...

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Main Authors: Wei HUANG, Miaomiao ZHANG, Ning WANG, Faqiang ZHAN, Fengjuan LIU, Suling WANG, Longyuan WU, Qiyong TANG, Lijuan ZHANG, Wei WANG
Format: Article
Language:zho
Published: The editorial department of Science and Technology of Food Industry 2025-03-01
Series:Shipin gongye ke-ji
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Online Access:http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024040394
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author Wei HUANG
Miaomiao ZHANG
Ning WANG
Faqiang ZHAN
Fengjuan LIU
Suling WANG
Longyuan WU
Qiyong TANG
Lijuan ZHANG
Wei WANG
author_facet Wei HUANG
Miaomiao ZHANG
Ning WANG
Faqiang ZHAN
Fengjuan LIU
Suling WANG
Longyuan WU
Qiyong TANG
Lijuan ZHANG
Wei WANG
author_sort Wei HUANG
collection DOAJ
description Gray mold is one of the main diseases in postharvest storage of grape. To explore the inhibition mechanism of acetophenone fumigation on Botrytis cinerea. When acetophenone was the lowest fungistatic concentration, the morphology and structure of the hypha of B. cinerea were observed by electron microscope. The contents of lipid and fatty acid of B. cinerea were determined by liquid chromatography-mass spectrometry, and the fumigation control effect of acetophenone on B. cinerea was also tested. The results showed that the minimum inhibitory concentratio (MIC) of acetophenone fumigation for B. cinerea was 62.50 μL/L. In vivo, the lesion diameter of the control group was 2.58 times that of the MIC acetophenone treatment group (P<0.05), while no symptoms were observed in the 2×MIC acetophenone treatment group. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) showed that the mycelial morphology of B. cinerea fumigated with acetophenone was rough, shrimpy, empty cell, reduced cytoplasmic matrix, and local plasmic wall separation. The morphology and structure of the control group were normal. Compared with the control group, after acetophenone fumigation, the levels of Cer in the lipids were significantly up-regulated, while the levels of phospholipids (PE, LBPA, PS, CL, PA) were significantly down regulated. According to the KEGG Pathway enrichment analysis, the AGE-RAGE signaling pathway and sphingolipid metabolism showed significant differences. There were 22 different fatty acids between the acetophenone fumigation group and the control group, 10 up-regulated and 12 down-regulated fatty acids, respectively. Acetophenone fumigation can destroy the morphology and structure of B. cinerea, control lipid synthesis by affecting sphingolipid metabolism and fatty acids, and inhibit the growth of B. cinerea both in vivo and in vitro. This study provides a theoretical basis for the development of fumigants for the control of postharvest gray mold in grape.
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spelling doaj-art-dd6e1f3885ad4cc7ba5a02cca83ea18f2025-08-20T01:57:28ZzhoThe editorial department of Science and Technology of Food IndustryShipin gongye ke-ji1002-03062025-03-0146633434110.13386/j.issn1002-0306.20240403942024040394-6Mechanism of Acetophenone Fumigation to Inhibit Postharvest Botrytis cinerea in GrapeWei HUANG0Miaomiao ZHANG1Ning WANG2Faqiang ZHAN3Fengjuan LIU4Suling WANG5Longyuan WU6Qiyong TANG7Lijuan ZHANG8Wei WANG9Xinjiang Laboratory of Special Environmental Microbiology, Institute of Applied Microbiology, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, ChinaXinjiang Laboratory of Special Environmental Microbiology, Institute of Applied Microbiology, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, ChinaXinjiang Laboratory of Special Environmental Microbiology, Institute of Applied Microbiology, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, ChinaXinjiang Laboratory of Special Environmental Microbiology, Institute of Applied Microbiology, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, ChinaInstitute of Agricultural Quality Standards and Testing Technology, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, ChinaXinjiang Laboratory of Special Environmental Microbiology, Institute of Applied Microbiology, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, ChinaXinjiang Laboratory of Special Environmental Microbiology, Institute of Applied Microbiology, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, ChinaXinjiang Laboratory of Special Environmental Microbiology, Institute of Applied Microbiology, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, ChinaXinjiang Laboratory of Special Environmental Microbiology, Institute of Applied Microbiology, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, ChinaXinjiang Laboratory of Special Environmental Microbiology, Institute of Applied Microbiology, Xinjiang Academy of Agricultural Sciences, Urumqi 830091, ChinaGray mold is one of the main diseases in postharvest storage of grape. To explore the inhibition mechanism of acetophenone fumigation on Botrytis cinerea. When acetophenone was the lowest fungistatic concentration, the morphology and structure of the hypha of B. cinerea were observed by electron microscope. The contents of lipid and fatty acid of B. cinerea were determined by liquid chromatography-mass spectrometry, and the fumigation control effect of acetophenone on B. cinerea was also tested. The results showed that the minimum inhibitory concentratio (MIC) of acetophenone fumigation for B. cinerea was 62.50 μL/L. In vivo, the lesion diameter of the control group was 2.58 times that of the MIC acetophenone treatment group (P<0.05), while no symptoms were observed in the 2×MIC acetophenone treatment group. Scanning electron microscopy (SEM) and transmission electron microscopy (TEM) showed that the mycelial morphology of B. cinerea fumigated with acetophenone was rough, shrimpy, empty cell, reduced cytoplasmic matrix, and local plasmic wall separation. The morphology and structure of the control group were normal. Compared with the control group, after acetophenone fumigation, the levels of Cer in the lipids were significantly up-regulated, while the levels of phospholipids (PE, LBPA, PS, CL, PA) were significantly down regulated. According to the KEGG Pathway enrichment analysis, the AGE-RAGE signaling pathway and sphingolipid metabolism showed significant differences. There were 22 different fatty acids between the acetophenone fumigation group and the control group, 10 up-regulated and 12 down-regulated fatty acids, respectively. Acetophenone fumigation can destroy the morphology and structure of B. cinerea, control lipid synthesis by affecting sphingolipid metabolism and fatty acids, and inhibit the growth of B. cinerea both in vivo and in vitro. This study provides a theoretical basis for the development of fumigants for the control of postharvest gray mold in grape.http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024040394acetophenonegrapesfumigationbotrytis cinereainhibition mechanism
spellingShingle Wei HUANG
Miaomiao ZHANG
Ning WANG
Faqiang ZHAN
Fengjuan LIU
Suling WANG
Longyuan WU
Qiyong TANG
Lijuan ZHANG
Wei WANG
Mechanism of Acetophenone Fumigation to Inhibit Postharvest Botrytis cinerea in Grape
Shipin gongye ke-ji
acetophenone
grapes
fumigation
botrytis cinerea
inhibition mechanism
title Mechanism of Acetophenone Fumigation to Inhibit Postharvest Botrytis cinerea in Grape
title_full Mechanism of Acetophenone Fumigation to Inhibit Postharvest Botrytis cinerea in Grape
title_fullStr Mechanism of Acetophenone Fumigation to Inhibit Postharvest Botrytis cinerea in Grape
title_full_unstemmed Mechanism of Acetophenone Fumigation to Inhibit Postharvest Botrytis cinerea in Grape
title_short Mechanism of Acetophenone Fumigation to Inhibit Postharvest Botrytis cinerea in Grape
title_sort mechanism of acetophenone fumigation to inhibit postharvest botrytis cinerea in grape
topic acetophenone
grapes
fumigation
botrytis cinerea
inhibition mechanism
url http://www.spgykj.com/cn/article/doi/10.13386/j.issn1002-0306.2024040394
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