Nonrigid Medical Image Registration by Finite-Element Deformable Sheet-Curve Models

Image-based change quantitation has been recognized as a promising tool for accurate assessment of tumor's early response to chemoprevention in cancer research. For example, various changes on breast density and vascularity in glandular tissue are the indicators of early response to treatment....

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Main Authors: Jianhua Xuan, Yue Wang, Matthew T. Freedman, Tulay Adali, Peter Shields
Format: Article
Language:English
Published: Wiley 2006-01-01
Series:International Journal of Biomedical Imaging
Online Access:http://dx.doi.org/10.1155/IJBI/2006/73430
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author Jianhua Xuan
Yue Wang
Matthew T. Freedman
Tulay Adali
Peter Shields
author_facet Jianhua Xuan
Yue Wang
Matthew T. Freedman
Tulay Adali
Peter Shields
author_sort Jianhua Xuan
collection DOAJ
description Image-based change quantitation has been recognized as a promising tool for accurate assessment of tumor's early response to chemoprevention in cancer research. For example, various changes on breast density and vascularity in glandular tissue are the indicators of early response to treatment. Accurate extraction of glandular tissue from pre- and postcontrast magnetic resonance (MR) images requires a nonrigid registration of sequential MR images embedded with local deformations. This paper reports a newly developed registration method that aligns MR breast images using finite-element deformable sheet-curve models. Specifically, deformable curves are constructed to match the boundaries dynamically, while a deformable sheet of thin-plate splines is designed to model complex local deformations. The experimental results on both digital phantoms and real MR breast images using the new method have been compared to point-based thin-plate-spline (TPS) approach, and have demonstrated a significant and robust improvement in both boundary alignment and local deformation recovery.
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institution Kabale University
issn 1687-4188
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language English
publishDate 2006-01-01
publisher Wiley
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series International Journal of Biomedical Imaging
spelling doaj-art-dd6866b5b985409abd5a2259397bc3582025-02-03T01:32:09ZengWileyInternational Journal of Biomedical Imaging1687-41881687-41962006-01-01200610.1155/IJBI/2006/7343073430Nonrigid Medical Image Registration by Finite-Element Deformable Sheet-Curve ModelsJianhua Xuan0Yue Wang1Matthew T. Freedman2Tulay Adali3Peter Shields4Department of Electrical Engineering and Computer Science, The Catholic University of America, Washington, DC 20064, USADepartment of Electrical and Computer Engineering, Virginia Polytechnic Institute and State University, Arlington, VA 22203, USADepartment of Oncology and the Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USADepartment of Computer Science and Electrical Engineering, University of Maryland, Baltimore County, Baltimore, MD 21250, USADepartment of Oncology and the Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC 20057, USAImage-based change quantitation has been recognized as a promising tool for accurate assessment of tumor's early response to chemoprevention in cancer research. For example, various changes on breast density and vascularity in glandular tissue are the indicators of early response to treatment. Accurate extraction of glandular tissue from pre- and postcontrast magnetic resonance (MR) images requires a nonrigid registration of sequential MR images embedded with local deformations. This paper reports a newly developed registration method that aligns MR breast images using finite-element deformable sheet-curve models. Specifically, deformable curves are constructed to match the boundaries dynamically, while a deformable sheet of thin-plate splines is designed to model complex local deformations. The experimental results on both digital phantoms and real MR breast images using the new method have been compared to point-based thin-plate-spline (TPS) approach, and have demonstrated a significant and robust improvement in both boundary alignment and local deformation recovery.http://dx.doi.org/10.1155/IJBI/2006/73430
spellingShingle Jianhua Xuan
Yue Wang
Matthew T. Freedman
Tulay Adali
Peter Shields
Nonrigid Medical Image Registration by Finite-Element Deformable Sheet-Curve Models
International Journal of Biomedical Imaging
title Nonrigid Medical Image Registration by Finite-Element Deformable Sheet-Curve Models
title_full Nonrigid Medical Image Registration by Finite-Element Deformable Sheet-Curve Models
title_fullStr Nonrigid Medical Image Registration by Finite-Element Deformable Sheet-Curve Models
title_full_unstemmed Nonrigid Medical Image Registration by Finite-Element Deformable Sheet-Curve Models
title_short Nonrigid Medical Image Registration by Finite-Element Deformable Sheet-Curve Models
title_sort nonrigid medical image registration by finite element deformable sheet curve models
url http://dx.doi.org/10.1155/IJBI/2006/73430
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AT matthewtfreedman nonrigidmedicalimageregistrationbyfiniteelementdeformablesheetcurvemodels
AT tulayadali nonrigidmedicalimageregistrationbyfiniteelementdeformablesheetcurvemodels
AT petershields nonrigidmedicalimageregistrationbyfiniteelementdeformablesheetcurvemodels