Base of Skull Metastatic Adenocarcinoma from the Breast 23 Years after the Primary Diagnosis
Breast cancer metastases to the base of the skull with concomitant infiltration into the paranasal sinuses and nasopharynx are exceptionally rare with only small numbers of reported literatures. Greenberg et al. in 1981 described five clinical syndromes with regards to the base of skull metastases a...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2020/2610597 |
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| author | Iylia Ajmal Othman Farah Dayana Zahedi Salina Husain |
| author_facet | Iylia Ajmal Othman Farah Dayana Zahedi Salina Husain |
| author_sort | Iylia Ajmal Othman |
| collection | DOAJ |
| description | Breast cancer metastases to the base of the skull with concomitant infiltration into the paranasal sinuses and nasopharynx are exceptionally rare with only small numbers of reported literatures. Greenberg et al. in 1981 described five clinical syndromes with regards to the base of skull metastases and the clinical presentation of each syndrome related to its anatomical location. Often, metastases to the base of the skull remain asymptomatic until the lesion has increased to a considerable size causing bony destruction and impingement to the surrounding structures. When involving the paranasal sinuses or nasopharynx, the most common presenting symptoms mimic those of rhinosinusitis and, hence, may delay the accurate diagnosis. We are reporting a case of base of skull metastasis from breast carcinoma, 23 years after the primary diagnosis. To the best of our knowledge, our case is the first case to report latent metastasis of more than 20 years. |
| format | Article |
| id | doaj-art-dd642a928ebf49ef9583ac09af032eec |
| institution | OA Journals |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-dd642a928ebf49ef9583ac09af032eec2025-08-20T02:21:30ZengWileyCase Reports in Medicine1687-96271687-96352020-01-01202010.1155/2020/26105972610597Base of Skull Metastatic Adenocarcinoma from the Breast 23 Years after the Primary DiagnosisIylia Ajmal Othman0Farah Dayana Zahedi1Salina Husain2Department of Otorhinolaryngology Head and Neck Surgery, Kulliyyah of Medicine, IUniversity Malaysia, Kuantan, Pahang, MalaysiaDepartment of Otorhinolaryngology Head & Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, MalaysiaDepartment of Otorhinolaryngology Head & Neck Surgery, Faculty of Medicine, Universiti Kebangsaan Malaysia, Kuala Lumpur, MalaysiaBreast cancer metastases to the base of the skull with concomitant infiltration into the paranasal sinuses and nasopharynx are exceptionally rare with only small numbers of reported literatures. Greenberg et al. in 1981 described five clinical syndromes with regards to the base of skull metastases and the clinical presentation of each syndrome related to its anatomical location. Often, metastases to the base of the skull remain asymptomatic until the lesion has increased to a considerable size causing bony destruction and impingement to the surrounding structures. When involving the paranasal sinuses or nasopharynx, the most common presenting symptoms mimic those of rhinosinusitis and, hence, may delay the accurate diagnosis. We are reporting a case of base of skull metastasis from breast carcinoma, 23 years after the primary diagnosis. To the best of our knowledge, our case is the first case to report latent metastasis of more than 20 years.http://dx.doi.org/10.1155/2020/2610597 |
| spellingShingle | Iylia Ajmal Othman Farah Dayana Zahedi Salina Husain Base of Skull Metastatic Adenocarcinoma from the Breast 23 Years after the Primary Diagnosis Case Reports in Medicine |
| title | Base of Skull Metastatic Adenocarcinoma from the Breast 23 Years after the Primary Diagnosis |
| title_full | Base of Skull Metastatic Adenocarcinoma from the Breast 23 Years after the Primary Diagnosis |
| title_fullStr | Base of Skull Metastatic Adenocarcinoma from the Breast 23 Years after the Primary Diagnosis |
| title_full_unstemmed | Base of Skull Metastatic Adenocarcinoma from the Breast 23 Years after the Primary Diagnosis |
| title_short | Base of Skull Metastatic Adenocarcinoma from the Breast 23 Years after the Primary Diagnosis |
| title_sort | base of skull metastatic adenocarcinoma from the breast 23 years after the primary diagnosis |
| url | http://dx.doi.org/10.1155/2020/2610597 |
| work_keys_str_mv | AT iyliaajmalothman baseofskullmetastaticadenocarcinomafromthebreast23yearsaftertheprimarydiagnosis AT farahdayanazahedi baseofskullmetastaticadenocarcinomafromthebreast23yearsaftertheprimarydiagnosis AT salinahusain baseofskullmetastaticadenocarcinomafromthebreast23yearsaftertheprimarydiagnosis |