Recent Advances on Bacterial Cellulose-Based Wound Management: Promises and Challenges

Wound healing is a therapeutic challenge due to the complexity of the wound. Various wounds could cause severe physiological trauma and bring social and economic burdens to the patient. The conventional wound healing treatments using bandages and gauze are limited particularly due to their susceptib...

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Main Authors: Hedaiat Moradpoor, Hossein Mohammadi, Mohsen Safaei, Hamid Reza Mozaffari, Roohollah Sharifi, Pourya Gorji, Abu Bakar Sulong, Norhamidi Muhamad, Mona Ebadi
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:International Journal of Polymer Science
Online Access:http://dx.doi.org/10.1155/2022/1214734
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author Hedaiat Moradpoor
Hossein Mohammadi
Mohsen Safaei
Hamid Reza Mozaffari
Roohollah Sharifi
Pourya Gorji
Abu Bakar Sulong
Norhamidi Muhamad
Mona Ebadi
author_facet Hedaiat Moradpoor
Hossein Mohammadi
Mohsen Safaei
Hamid Reza Mozaffari
Roohollah Sharifi
Pourya Gorji
Abu Bakar Sulong
Norhamidi Muhamad
Mona Ebadi
author_sort Hedaiat Moradpoor
collection DOAJ
description Wound healing is a therapeutic challenge due to the complexity of the wound. Various wounds could cause severe physiological trauma and bring social and economic burdens to the patient. The conventional wound healing treatments using bandages and gauze are limited particularly due to their susceptibility to infection. Different types of wound dressing have developed in different physical forms such as sponges, hydrocolloids, films, membranes, and hydrogels. Each of these formulations possesses distinct characteristics making them appropriate for the treatment of a specific wound. In this review, the pathology and microbiology of wounds are introduced. Then, the most recent progress on bacterial cellulose- (BC-) based wound dressing discussed and highlighted their antibacterial and reepithelization properties in vitro and in vivo wound closure. Finally, the challenges and future perspectives on the development of BC-based wound dressing biomaterials are outlined.
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institution Kabale University
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publishDate 2022-01-01
publisher Wiley
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series International Journal of Polymer Science
spelling doaj-art-dd626abdc9724673a0b6e127a4200ab52025-02-03T06:13:30ZengWileyInternational Journal of Polymer Science1687-94302022-01-01202210.1155/2022/1214734Recent Advances on Bacterial Cellulose-Based Wound Management: Promises and ChallengesHedaiat Moradpoor0Hossein Mohammadi1Mohsen Safaei2Hamid Reza Mozaffari3Roohollah Sharifi4Pourya Gorji5Abu Bakar Sulong6Norhamidi Muhamad7Mona Ebadi8Department of ProsthodonticsSchool of Mechanical EngineeringAdvanced Dental Sciences Research CenterDepartment of Oral and Maxillofacial MedicineDepartment of EndodonticsStudents Research CommitteeDepartment of Mechanical and Manufacturing EngineeringDepartment of Mechanical and Manufacturing EngineeringInstitute of Advanced Technology (ITMA)Wound healing is a therapeutic challenge due to the complexity of the wound. Various wounds could cause severe physiological trauma and bring social and economic burdens to the patient. The conventional wound healing treatments using bandages and gauze are limited particularly due to their susceptibility to infection. Different types of wound dressing have developed in different physical forms such as sponges, hydrocolloids, films, membranes, and hydrogels. Each of these formulations possesses distinct characteristics making them appropriate for the treatment of a specific wound. In this review, the pathology and microbiology of wounds are introduced. Then, the most recent progress on bacterial cellulose- (BC-) based wound dressing discussed and highlighted their antibacterial and reepithelization properties in vitro and in vivo wound closure. Finally, the challenges and future perspectives on the development of BC-based wound dressing biomaterials are outlined.http://dx.doi.org/10.1155/2022/1214734
spellingShingle Hedaiat Moradpoor
Hossein Mohammadi
Mohsen Safaei
Hamid Reza Mozaffari
Roohollah Sharifi
Pourya Gorji
Abu Bakar Sulong
Norhamidi Muhamad
Mona Ebadi
Recent Advances on Bacterial Cellulose-Based Wound Management: Promises and Challenges
International Journal of Polymer Science
title Recent Advances on Bacterial Cellulose-Based Wound Management: Promises and Challenges
title_full Recent Advances on Bacterial Cellulose-Based Wound Management: Promises and Challenges
title_fullStr Recent Advances on Bacterial Cellulose-Based Wound Management: Promises and Challenges
title_full_unstemmed Recent Advances on Bacterial Cellulose-Based Wound Management: Promises and Challenges
title_short Recent Advances on Bacterial Cellulose-Based Wound Management: Promises and Challenges
title_sort recent advances on bacterial cellulose based wound management promises and challenges
url http://dx.doi.org/10.1155/2022/1214734
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