The quality of life of colorectal cancer patients attending the cancer center in addis Ababa, Ethiopia
Abstract Background Globally, colorectal cancer (CRC) is the third most common type of cancer and the second most deadly. CRC significantly impairs patients’ overall and health-related quality of life, as well as their psychological and physical function. However, in Ethiopia, there is insufficient...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-04-01
|
| Series: | BMC Cancer |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12885-025-14122-y |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849713789895704576 |
|---|---|
| author | Helen GebreLibanos Girma Taye Abigiya Wondimagegnehu Jilicha Diribi Feyisa Tsion Afework Ephrem Gebreegziabher Zenawi Hagos Gufue |
| author_facet | Helen GebreLibanos Girma Taye Abigiya Wondimagegnehu Jilicha Diribi Feyisa Tsion Afework Ephrem Gebreegziabher Zenawi Hagos Gufue |
| author_sort | Helen GebreLibanos |
| collection | DOAJ |
| description | Abstract Background Globally, colorectal cancer (CRC) is the third most common type of cancer and the second most deadly. CRC significantly impairs patients’ overall and health-related quality of life, as well as their psychological and physical function. However, in Ethiopia, there is insufficient local evidence about the quality of life of patients with colorectal cancer. Hence, this study aimed to assess the quality of life of adult colorectal cancer patients who have follow-ups at the cancer center in Tikur Anbessa Specialized Hospital in Addis Ababa, Ethiopia. Methods An institutional-based cross-sectional study was conducted among 159 colorectal cancer patients attending the Tikur Anbessa Specialized Hospital Cancer Center from February to April 2019. The validated Amharic version of the European Organisation for Research and Treatment of Cancer Core 30 questionnaire (EORTC QLQ C-30) and the disease-specific colorectal cancer questionnaire (EORTC QLQ CR-29) were used. A binary logistic regression model was used to identify the factors associated with quality of life. The adjusted measure of effect (AOR) with a 95% CI was presented and P < 0.05 was used to declare statistical significance. Results There were 159 colorectal cancer patients, 89 of whom were male, and the median time from diagnosis was 12.5 months. The patients had a low global health status score with a mean (± SD) of 52.88 ± 21.02. Being employed (AOR = 3.41; 95% CI 1.15, 10.17), early-stage clinical diagnosis (AOR = 4.98; 95% CI 1.51, 16.4), physical functioning (AOR = 1.04, 95% CI 1.01, 1.06), and social functioning (AOR = 1.02; 95% CI 1.01, 1.04) were associated with good quality of life. Whereas, being female (AOR = 0.16; 95% CI 0.05, 0.52), having financial difficulty (AOR = 0.98; 95% CI 0.96, 0.99), and having blood and mucus in the stool (AOR = 0.94; 95% CI 0.91, 0.96) were associated with poor quality of life. Conclusion In our study, half of our study participants had poor quality of life. The responsible stakeholders should identify and address the patients’ respective symptoms. Female patients, those in severe clinical stages, unemployed patients, those experiencing financial difficulties, and those with blood and mucus in their stool should receive due attention. |
| format | Article |
| id | doaj-art-dd5809a0d3a044e5b818cfc4f115ad3a |
| institution | DOAJ |
| issn | 1471-2407 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Cancer |
| spelling | doaj-art-dd5809a0d3a044e5b818cfc4f115ad3a2025-08-20T03:13:53ZengBMCBMC Cancer1471-24072025-04-012511910.1186/s12885-025-14122-yThe quality of life of colorectal cancer patients attending the cancer center in addis Ababa, EthiopiaHelen GebreLibanos0Girma Taye1Abigiya Wondimagegnehu2Jilicha Diribi Feyisa3Tsion Afework4Ephrem Gebreegziabher5Zenawi Hagos Gufue6Department of Epidemiology, School of Public Health, Debre Birhan UniversityDepartment of Epidemiology and Biostatistics, School of Public Health, Addis Ababa UniversityDepartment of Epidemiology and Biostatistics, School of Public Health, Addis Ababa UniversityDepartment of Radiation Oncology and Applied Sciences, Dartmouth Cancer CenterDepartment of Epidemiology and Biostatistics, School of Public Health, Addis Ababa UniversitySchool of Pharmacy, Addis Ababa UniversityDepartment of Public Health, College of Medicine and Health Sciences, Adigrat UniversityAbstract Background Globally, colorectal cancer (CRC) is the third most common type of cancer and the second most deadly. CRC significantly impairs patients’ overall and health-related quality of life, as well as their psychological and physical function. However, in Ethiopia, there is insufficient local evidence about the quality of life of patients with colorectal cancer. Hence, this study aimed to assess the quality of life of adult colorectal cancer patients who have follow-ups at the cancer center in Tikur Anbessa Specialized Hospital in Addis Ababa, Ethiopia. Methods An institutional-based cross-sectional study was conducted among 159 colorectal cancer patients attending the Tikur Anbessa Specialized Hospital Cancer Center from February to April 2019. The validated Amharic version of the European Organisation for Research and Treatment of Cancer Core 30 questionnaire (EORTC QLQ C-30) and the disease-specific colorectal cancer questionnaire (EORTC QLQ CR-29) were used. A binary logistic regression model was used to identify the factors associated with quality of life. The adjusted measure of effect (AOR) with a 95% CI was presented and P < 0.05 was used to declare statistical significance. Results There were 159 colorectal cancer patients, 89 of whom were male, and the median time from diagnosis was 12.5 months. The patients had a low global health status score with a mean (± SD) of 52.88 ± 21.02. Being employed (AOR = 3.41; 95% CI 1.15, 10.17), early-stage clinical diagnosis (AOR = 4.98; 95% CI 1.51, 16.4), physical functioning (AOR = 1.04, 95% CI 1.01, 1.06), and social functioning (AOR = 1.02; 95% CI 1.01, 1.04) were associated with good quality of life. Whereas, being female (AOR = 0.16; 95% CI 0.05, 0.52), having financial difficulty (AOR = 0.98; 95% CI 0.96, 0.99), and having blood and mucus in the stool (AOR = 0.94; 95% CI 0.91, 0.96) were associated with poor quality of life. Conclusion In our study, half of our study participants had poor quality of life. The responsible stakeholders should identify and address the patients’ respective symptoms. Female patients, those in severe clinical stages, unemployed patients, those experiencing financial difficulties, and those with blood and mucus in their stool should receive due attention.https://doi.org/10.1186/s12885-025-14122-yColorectal cancerQuality of lifeEORTC QLQ CR-29EORTC QLQ C-30Ethiopia |
| spellingShingle | Helen GebreLibanos Girma Taye Abigiya Wondimagegnehu Jilicha Diribi Feyisa Tsion Afework Ephrem Gebreegziabher Zenawi Hagos Gufue The quality of life of colorectal cancer patients attending the cancer center in addis Ababa, Ethiopia BMC Cancer Colorectal cancer Quality of life EORTC QLQ CR-29 EORTC QLQ C-30 Ethiopia |
| title | The quality of life of colorectal cancer patients attending the cancer center in addis Ababa, Ethiopia |
| title_full | The quality of life of colorectal cancer patients attending the cancer center in addis Ababa, Ethiopia |
| title_fullStr | The quality of life of colorectal cancer patients attending the cancer center in addis Ababa, Ethiopia |
| title_full_unstemmed | The quality of life of colorectal cancer patients attending the cancer center in addis Ababa, Ethiopia |
| title_short | The quality of life of colorectal cancer patients attending the cancer center in addis Ababa, Ethiopia |
| title_sort | quality of life of colorectal cancer patients attending the cancer center in addis ababa ethiopia |
| topic | Colorectal cancer Quality of life EORTC QLQ CR-29 EORTC QLQ C-30 Ethiopia |
| url | https://doi.org/10.1186/s12885-025-14122-y |
| work_keys_str_mv | AT helengebrelibanos thequalityoflifeofcolorectalcancerpatientsattendingthecancercenterinaddisababaethiopia AT girmataye thequalityoflifeofcolorectalcancerpatientsattendingthecancercenterinaddisababaethiopia AT abigiyawondimagegnehu thequalityoflifeofcolorectalcancerpatientsattendingthecancercenterinaddisababaethiopia AT jilichadiribifeyisa thequalityoflifeofcolorectalcancerpatientsattendingthecancercenterinaddisababaethiopia AT tsionafework thequalityoflifeofcolorectalcancerpatientsattendingthecancercenterinaddisababaethiopia AT ephremgebreegziabher thequalityoflifeofcolorectalcancerpatientsattendingthecancercenterinaddisababaethiopia AT zenawihagosgufue thequalityoflifeofcolorectalcancerpatientsattendingthecancercenterinaddisababaethiopia AT helengebrelibanos qualityoflifeofcolorectalcancerpatientsattendingthecancercenterinaddisababaethiopia AT girmataye qualityoflifeofcolorectalcancerpatientsattendingthecancercenterinaddisababaethiopia AT abigiyawondimagegnehu qualityoflifeofcolorectalcancerpatientsattendingthecancercenterinaddisababaethiopia AT jilichadiribifeyisa qualityoflifeofcolorectalcancerpatientsattendingthecancercenterinaddisababaethiopia AT tsionafework qualityoflifeofcolorectalcancerpatientsattendingthecancercenterinaddisababaethiopia AT ephremgebreegziabher qualityoflifeofcolorectalcancerpatientsattendingthecancercenterinaddisababaethiopia AT zenawihagosgufue qualityoflifeofcolorectalcancerpatientsattendingthecancercenterinaddisababaethiopia |