PHARMACOEPIDEMIOLOGICAL MONITORING OF ANTIDEPRESSANT USAGE IN PATIENTS WITH ANXIOUS AND DEPRESSIVE SYNDROMES IN INTERNAL MEDICINE

Aim. To study antidepressant usage in treatment of anxious and depressive disorders in real internal medicine practice.Material and methods. Retrospective analysis of 290 charts of patients, which were observed in Pskov region hospital from 2004 to 2005 was held. All patients suffered from different...

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Main Authors: N. V. Ivanova, B. B. Fischman, G. I. Schwartsman, L. A. Fomenko, A. A. Abdulin, M. S. Kazymov, I. V. Samsonova, M. A. Bobyr
Format: Article
Language:English
Published: Столичная издательская компания 2015-12-01
Series:Рациональная фармакотерапия в кардиологии
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Online Access:https://www.rpcardio.online/jour/article/view/451
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author N. V. Ivanova
B. B. Fischman
G. I. Schwartsman
L. A. Fomenko
A. A. Abdulin
M. S. Kazymov
I. V. Samsonova
M. A. Bobyr
author_facet N. V. Ivanova
B. B. Fischman
G. I. Schwartsman
L. A. Fomenko
A. A. Abdulin
M. S. Kazymov
I. V. Samsonova
M. A. Bobyr
author_sort N. V. Ivanova
collection DOAJ
description Aim. To study antidepressant usage in treatment of anxious and depressive disorders in real internal medicine practice.Material and methods. Retrospective analysis of 290 charts of patients, which were observed in Pskov region hospital from 2004 to 2005 was held. All patients suffered from different internal diseases and were treated with antidepressants because of anxious and depressive concomitant disorders.Results. Arterial hypertension observed in 28% of patients, ischemic heart disease – in 20%, heart failure – in 14%, cerebrovascular and peripheral nervous system diseases – in 18% and gastroduodenal diseases – in 20% of patients. Amitriptyline took the first place (49%) among antidepressant prescriptions. Next antidepressants according to prescription popularity were paroxetine (22%) and tianeptine (12%). Rate of other antidepressant prescriptions were not higher than 5%. There were differences in antidepressant prescriptions between physicians of different specialties.Conclusion. Reasonable approaches should be used to choose antidepressants. Selective serotonin reuptake inhibitors have benefit for the therapy of concomitant anxious and depressive disorders due to their good tolerability. Nevertheless tricyclic antidepressants are essential in some clinical situations.
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series Рациональная фармакотерапия в кардиологии
spelling doaj-art-dd4e055553e84cac8dd29e77894a555c2025-08-23T10:00:20ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532015-12-01336910.20996/1819-6446-2007-3-3-6-9451PHARMACOEPIDEMIOLOGICAL MONITORING OF ANTIDEPRESSANT USAGE IN PATIENTS WITH ANXIOUS AND DEPRESSIVE SYNDROMES IN INTERNAL MEDICINEN. V. Ivanova0B. B. Fischman1G. I. Schwartsman2L. A. Fomenko3A. A. Abdulin4M. S. Kazymov5I. V. Samsonova6M. A. Bobyr7St. Petersburg Medical Academy of postgraduate education; St. Petersburg State Medical Academy named after I.I. Mechnikov; Novgorod State University named after Jaroslaw the WiseSt. Petersburg Medical Academy of postgraduate education; St. Petersburg State Medical Academy named after I.I. Mechnikov; Novgorod State University named after Jaroslaw the WiseSt. Petersburg Medical Academy of postgraduate education; St. Petersburg State Medical Academy named after I.I. Mechnikov; Novgorod State University named after Jaroslaw the WiseSt. Petersburg Medical Academy of postgraduate education; St. Petersburg State Medical Academy named after I.I. Mechnikov; Novgorod State University named after Jaroslaw the WiseSt. Petersburg Medical Academy of postgraduate education; St. Petersburg State Medical Academy named after I.I. Mechnikov; Novgorod State University named after Jaroslaw the WiseSt. Petersburg Medical Academy of postgraduate education; St. Petersburg State Medical Academy named after I.I. Mechnikov; Novgorod State University named after Jaroslaw the WiseSt. Petersburg Medical Academy of postgraduate education; St. Petersburg State Medical Academy named after I.I. Mechnikov; Novgorod State University named after Jaroslaw the WiseSt. Petersburg Medical Academy of postgraduate education; St. Petersburg State Medical Academy named after I.I. Mechnikov; Novgorod State University named after Jaroslaw the WiseAim. To study antidepressant usage in treatment of anxious and depressive disorders in real internal medicine practice.Material and methods. Retrospective analysis of 290 charts of patients, which were observed in Pskov region hospital from 2004 to 2005 was held. All patients suffered from different internal diseases and were treated with antidepressants because of anxious and depressive concomitant disorders.Results. Arterial hypertension observed in 28% of patients, ischemic heart disease – in 20%, heart failure – in 14%, cerebrovascular and peripheral nervous system diseases – in 18% and gastroduodenal diseases – in 20% of patients. Amitriptyline took the first place (49%) among antidepressant prescriptions. Next antidepressants according to prescription popularity were paroxetine (22%) and tianeptine (12%). Rate of other antidepressant prescriptions were not higher than 5%. There were differences in antidepressant prescriptions between physicians of different specialties.Conclusion. Reasonable approaches should be used to choose antidepressants. Selective serotonin reuptake inhibitors have benefit for the therapy of concomitant anxious and depressive disorders due to their good tolerability. Nevertheless tricyclic antidepressants are essential in some clinical situations.https://www.rpcardio.online/jour/article/view/451comorbidityanxious and depressive disorderspsychopharmacotherapyantidepressants
spellingShingle N. V. Ivanova
B. B. Fischman
G. I. Schwartsman
L. A. Fomenko
A. A. Abdulin
M. S. Kazymov
I. V. Samsonova
M. A. Bobyr
PHARMACOEPIDEMIOLOGICAL MONITORING OF ANTIDEPRESSANT USAGE IN PATIENTS WITH ANXIOUS AND DEPRESSIVE SYNDROMES IN INTERNAL MEDICINE
Рациональная фармакотерапия в кардиологии
comorbidity
anxious and depressive disorders
psychopharmacotherapy
antidepressants
title PHARMACOEPIDEMIOLOGICAL MONITORING OF ANTIDEPRESSANT USAGE IN PATIENTS WITH ANXIOUS AND DEPRESSIVE SYNDROMES IN INTERNAL MEDICINE
title_full PHARMACOEPIDEMIOLOGICAL MONITORING OF ANTIDEPRESSANT USAGE IN PATIENTS WITH ANXIOUS AND DEPRESSIVE SYNDROMES IN INTERNAL MEDICINE
title_fullStr PHARMACOEPIDEMIOLOGICAL MONITORING OF ANTIDEPRESSANT USAGE IN PATIENTS WITH ANXIOUS AND DEPRESSIVE SYNDROMES IN INTERNAL MEDICINE
title_full_unstemmed PHARMACOEPIDEMIOLOGICAL MONITORING OF ANTIDEPRESSANT USAGE IN PATIENTS WITH ANXIOUS AND DEPRESSIVE SYNDROMES IN INTERNAL MEDICINE
title_short PHARMACOEPIDEMIOLOGICAL MONITORING OF ANTIDEPRESSANT USAGE IN PATIENTS WITH ANXIOUS AND DEPRESSIVE SYNDROMES IN INTERNAL MEDICINE
title_sort pharmacoepidemiological monitoring of antidepressant usage in patients with anxious and depressive syndromes in internal medicine
topic comorbidity
anxious and depressive disorders
psychopharmacotherapy
antidepressants
url https://www.rpcardio.online/jour/article/view/451
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