Evaluation of two portable pupillometers to assess clinical utility

Background: Pupillometers have been proposed as clinical assessment tools. We compared two pupillometers to assess measurement agreement. Materials & methods: We enrolled 30 subjects and simultaneously measured the pupil diameter and light reflex amplitude with an iPhone pupillometer and a porta...

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Main Authors: Rachel Eshima McKay, Michael A Kohn, Elliot S Schwartz, Merlin D Larson
Format: Article
Language:English
Published: Aldus Press 2020-12-01
Series:Concussion
Subjects:
Online Access:https://www.futuremedicine.com/doi/10.2217/cnc-2020-0016
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author Rachel Eshima McKay
Michael A Kohn
Elliot S Schwartz
Merlin D Larson
author_facet Rachel Eshima McKay
Michael A Kohn
Elliot S Schwartz
Merlin D Larson
author_sort Rachel Eshima McKay
collection DOAJ
description Background: Pupillometers have been proposed as clinical assessment tools. We compared two pupillometers to assess measurement agreement. Materials & methods: We enrolled 30 subjects and simultaneously measured the pupil diameter and light reflex amplitude with an iPhone pupillometer and a portable infrared pupillometer. We then enrolled 40 additional subjects and made serial measurements with each device. Results: Failure occurred in 30% of attempts made with the iPhone pupillometer compared with 4% of attempts made with the infrared pupillometer (Fisher’s exact p = 0.0001). Method comparison of the two devices used simultaneously showed significant disagreement in dynamic measurements. Conclusion: The iPhone pupillometer had poor repeatability and suggests that it is not a practical tool to support clinical decisions.
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publishDate 2020-12-01
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series Concussion
spelling doaj-art-dd486bdf4c0a433fb94fb57cef0c2a6f2025-08-20T02:04:20ZengAldus PressConcussion2056-32992020-12-015410.2217/cnc-2020-0016Evaluation of two portable pupillometers to assess clinical utilityRachel Eshima McKay0Michael A Kohn1Elliot S Schwartz2Merlin D Larson31Department of Anesthesia & Perioperative Care, Professor, University of California San Francisco, CA 94143, USA2Department of Epidemiology & Biostatistics, Professor, University of California San Francisco, CA 94143, USA3Department of Anesthesia & Perioperative Care, Resident in Anesthesia, University of California San Francisco, CA 94143, USA4Department of Anesthesia & Perioperative Care, Professor Emeritus, University of California San Francisco, CA 94143, USABackground: Pupillometers have been proposed as clinical assessment tools. We compared two pupillometers to assess measurement agreement. Materials & methods: We enrolled 30 subjects and simultaneously measured the pupil diameter and light reflex amplitude with an iPhone pupillometer and a portable infrared pupillometer. We then enrolled 40 additional subjects and made serial measurements with each device. Results: Failure occurred in 30% of attempts made with the iPhone pupillometer compared with 4% of attempts made with the infrared pupillometer (Fisher’s exact p = 0.0001). Method comparison of the two devices used simultaneously showed significant disagreement in dynamic measurements. Conclusion: The iPhone pupillometer had poor repeatability and suggests that it is not a practical tool to support clinical decisions.https://www.futuremedicine.com/doi/10.2217/cnc-2020-0016concussioneyepupilpupillary light reflexpupillometry
spellingShingle Rachel Eshima McKay
Michael A Kohn
Elliot S Schwartz
Merlin D Larson
Evaluation of two portable pupillometers to assess clinical utility
Concussion
concussion
eye
pupil
pupillary light reflex
pupillometry
title Evaluation of two portable pupillometers to assess clinical utility
title_full Evaluation of two portable pupillometers to assess clinical utility
title_fullStr Evaluation of two portable pupillometers to assess clinical utility
title_full_unstemmed Evaluation of two portable pupillometers to assess clinical utility
title_short Evaluation of two portable pupillometers to assess clinical utility
title_sort evaluation of two portable pupillometers to assess clinical utility
topic concussion
eye
pupil
pupillary light reflex
pupillometry
url https://www.futuremedicine.com/doi/10.2217/cnc-2020-0016
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AT elliotsschwartz evaluationoftwoportablepupillometerstoassessclinicalutility
AT merlindlarson evaluationoftwoportablepupillometerstoassessclinicalutility