A newly modified nerve-sparing radical hysterectomy technique with analysis of short-term oncologic, surgical, and functional outcomes
ObjectiveThis study aims to investigate a newly modified approach to nerve-sparing radical hysterectomy.Subjects and MethodsPathological large-section staining of the entire paracolpium from specimens obtained after radical hysterectomy was performed to examine its structural composition and identif...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2025-06-01
|
| Series: | Frontiers in Oncology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2025.1555483/full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849696825543491584 |
|---|---|
| author | Shichao Han Shichao Han Xinyou Wang Xinyou Wang Jinming Zhu Ya Li Ya Li Jing Na Jing Na Jun Wang Jun Wang |
| author_facet | Shichao Han Shichao Han Xinyou Wang Xinyou Wang Jinming Zhu Ya Li Ya Li Jing Na Jing Na Jun Wang Jun Wang |
| author_sort | Shichao Han |
| collection | DOAJ |
| description | ObjectiveThis study aims to investigate a newly modified approach to nerve-sparing radical hysterectomy.Subjects and MethodsPathological large-section staining of the entire paracolpium from specimens obtained after radical hysterectomy was performed to examine its structural composition and identify the course and distribution of the pelvic plexus and its branches. Based on the analysis of nerve pathways and locations, a total of 55 cases of modified nerve-sparing surgeries preserving pelvic autonomic function were conducted.ResultsAll radical hysterectomies were performed in accordance with the principles of membrane anatomy. Postoperative pathological large-section staining of the paracolpium, combined with microscopic examination, revealed three distinct planes from ventral to dorsal: a vascular plane, consisting of the deep uterine vein and bladder venous plexus draining into the deep uterine vein; a neural plane, formed by the pelvic plexus and its nerve branches; and a ligamentous plane, consisting of the sacral ligament. In clinical practice, utilizing the three-plane structure of the paracolpium and medially lifting the vascular plane facilitated safe, reliable dissection, exposure, and preservation of pelvic autonomic nerve function.Through clinical practice, follow-up, and analysis of 55 cases, it was observed that combining the concept of membrane anatomy with the three-plane anatomical structure of the paracolpium not only enables nerve-sparing radical hysterectomy as a bloodless surgical procedure but also ensures optimal nerve preservation, favorable oncological outcomes, and a significant reduction in perioperative complications.ConclusionGuided by the principles of membrane anatomy and the three-plane theory of the paracolpium, nerve-sparing radical hysterectomy facilitates precise preservation of pelvic autonomic nerve function in a bloodless manner, while achieving favorable oncological outcomes. |
| format | Article |
| id | doaj-art-dd386e69341b41e4b5c0f52914a8fcdc |
| institution | DOAJ |
| issn | 2234-943X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj-art-dd386e69341b41e4b5c0f52914a8fcdc2025-08-20T03:19:20ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2025-06-011510.3389/fonc.2025.15554831555483A newly modified nerve-sparing radical hysterectomy technique with analysis of short-term oncologic, surgical, and functional outcomesShichao Han0Shichao Han1Xinyou Wang2Xinyou Wang3Jinming Zhu4Ya Li5Ya Li6Jing Na7Jing Na8Jun Wang9Jun Wang10Department of Gynecology and Obstetrics, The Second Affiliated Hospital of Dalian Medical University, Dalian, ChinaDepartment of Obstetrics and Gynecology, the Second Clinical College of Dalian Medical University, Dalian, ChinaDepartment of Gynecology and Obstetrics, The Second Affiliated Hospital of Dalian Medical University, Dalian, ChinaDepartment of Obstetrics and Gynecology, the Second Clinical College of Dalian Medical University, Dalian, ChinaOncology Department, Affiliated Zhongshan Hospital of Dalian University, Dalian, ChinaDepartment of Gynecology and Obstetrics, The Second Affiliated Hospital of Dalian Medical University, Dalian, ChinaDepartment of Obstetrics and Gynecology, the Second Clinical College of Dalian Medical University, Dalian, ChinaDepartment of Gynecology and Obstetrics, The Second Affiliated Hospital of Dalian Medical University, Dalian, ChinaDepartment of Obstetrics and Gynecology, the Second Clinical College of Dalian Medical University, Dalian, ChinaDepartment of Gynecology and Obstetrics, The Second Affiliated Hospital of Dalian Medical University, Dalian, ChinaDepartment of Obstetrics and Gynecology, the Second Clinical College of Dalian Medical University, Dalian, ChinaObjectiveThis study aims to investigate a newly modified approach to nerve-sparing radical hysterectomy.Subjects and MethodsPathological large-section staining of the entire paracolpium from specimens obtained after radical hysterectomy was performed to examine its structural composition and identify the course and distribution of the pelvic plexus and its branches. Based on the analysis of nerve pathways and locations, a total of 55 cases of modified nerve-sparing surgeries preserving pelvic autonomic function were conducted.ResultsAll radical hysterectomies were performed in accordance with the principles of membrane anatomy. Postoperative pathological large-section staining of the paracolpium, combined with microscopic examination, revealed three distinct planes from ventral to dorsal: a vascular plane, consisting of the deep uterine vein and bladder venous plexus draining into the deep uterine vein; a neural plane, formed by the pelvic plexus and its nerve branches; and a ligamentous plane, consisting of the sacral ligament. In clinical practice, utilizing the three-plane structure of the paracolpium and medially lifting the vascular plane facilitated safe, reliable dissection, exposure, and preservation of pelvic autonomic nerve function.Through clinical practice, follow-up, and analysis of 55 cases, it was observed that combining the concept of membrane anatomy with the three-plane anatomical structure of the paracolpium not only enables nerve-sparing radical hysterectomy as a bloodless surgical procedure but also ensures optimal nerve preservation, favorable oncological outcomes, and a significant reduction in perioperative complications.ConclusionGuided by the principles of membrane anatomy and the three-plane theory of the paracolpium, nerve-sparing radical hysterectomy facilitates precise preservation of pelvic autonomic nerve function in a bloodless manner, while achieving favorable oncological outcomes.https://www.frontiersin.org/articles/10.3389/fonc.2025.1555483/fullcervical cancerradical hysterectomynerve-sparingmembrane bridgeembryonic compartment |
| spellingShingle | Shichao Han Shichao Han Xinyou Wang Xinyou Wang Jinming Zhu Ya Li Ya Li Jing Na Jing Na Jun Wang Jun Wang A newly modified nerve-sparing radical hysterectomy technique with analysis of short-term oncologic, surgical, and functional outcomes Frontiers in Oncology cervical cancer radical hysterectomy nerve-sparing membrane bridge embryonic compartment |
| title | A newly modified nerve-sparing radical hysterectomy technique with analysis of short-term oncologic, surgical, and functional outcomes |
| title_full | A newly modified nerve-sparing radical hysterectomy technique with analysis of short-term oncologic, surgical, and functional outcomes |
| title_fullStr | A newly modified nerve-sparing radical hysterectomy technique with analysis of short-term oncologic, surgical, and functional outcomes |
| title_full_unstemmed | A newly modified nerve-sparing radical hysterectomy technique with analysis of short-term oncologic, surgical, and functional outcomes |
| title_short | A newly modified nerve-sparing radical hysterectomy technique with analysis of short-term oncologic, surgical, and functional outcomes |
| title_sort | newly modified nerve sparing radical hysterectomy technique with analysis of short term oncologic surgical and functional outcomes |
| topic | cervical cancer radical hysterectomy nerve-sparing membrane bridge embryonic compartment |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2025.1555483/full |
| work_keys_str_mv | AT shichaohan anewlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT shichaohan anewlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT xinyouwang anewlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT xinyouwang anewlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT jinmingzhu anewlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT yali anewlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT yali anewlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT jingna anewlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT jingna anewlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT junwang anewlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT junwang anewlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT shichaohan newlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT shichaohan newlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT xinyouwang newlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT xinyouwang newlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT jinmingzhu newlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT yali newlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT yali newlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT jingna newlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT jingna newlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT junwang newlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes AT junwang newlymodifiednervesparingradicalhysterectomytechniquewithanalysisofshorttermoncologicsurgicalandfunctionaloutcomes |