Prevalence and risk factors of falls in people on hemodialysis: a systematic review and meta-analysis

Objectives This study aims to systematically quantify the prevalence of falls in people on hemodialysis and to assess risk factors associated with falls by synthesizing emerging best evidence.Methods A comprehensive search was conducted across ten databases from their inception to February 27, 2025....

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Main Authors: Jiayi Tang, Bei Wang, Qin Yuan, Xiaobo Li
Format: Article
Language:English
Published: Taylor & Francis Group 2025-12-01
Series:Renal Failure
Subjects:
Online Access:https://www.tandfonline.com/doi/10.1080/0886022X.2025.2485375
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author Jiayi Tang
Bei Wang
Qin Yuan
Xiaobo Li
author_facet Jiayi Tang
Bei Wang
Qin Yuan
Xiaobo Li
author_sort Jiayi Tang
collection DOAJ
description Objectives This study aims to systematically quantify the prevalence of falls in people on hemodialysis and to assess risk factors associated with falls by synthesizing emerging best evidence.Methods A comprehensive search was conducted across ten databases from their inception to February 27, 2025. The research team independently conducted study selection, quality assessments, data extraction, and analyses of all included studies. Meta-analysis was performed using random-effects and fixed-effects models. The PRISMA guidelines were used to report the systematic review and meta-analysis.Results A total of 31 studies, comprising 191,800 individuals, were included in the analysis. The pooled prevalence of falls in people on hemodialysis was 27.1%. The meta-analysis of risk factors included 19 studies. After controlling for confounding variables, 12 risk factors were associated with falls, including older age, female gender, longer dialysis duration, diabetes mellitus, peripheral vascular disease, paralysis, antidepressant use, frailty, use of walking aids, malnutrition, intradialytic hypotension, and low hemoglobin levels.Conclusions This study provides an updated, evidence-based assessment of the prevalence and risk factors of falls in people on hemodialysis, confirming their multifactorial etiology. Screening and interventions should be implemented promptly to mitigate the adverse outcomes of falls in people on hemodialysis.Registration number PROSPERO CRD42024525375.
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series Renal Failure
spelling doaj-art-dd33044e32254cc085eeb1b928c4b89c2025-08-20T02:11:26ZengTaylor & Francis GroupRenal Failure0886-022X1525-60492025-12-0147110.1080/0886022X.2025.2485375Prevalence and risk factors of falls in people on hemodialysis: a systematic review and meta-analysisJiayi Tang0Bei Wang1Qin Yuan2Xiaobo Li3The First Hospital of China Medical University, Shenyang, ChinaNursing School, China Medical University, Shenyang, ChinaNursing School, China Medical University, Shenyang, ChinaThe First Hospital of China Medical University, Shenyang, ChinaObjectives This study aims to systematically quantify the prevalence of falls in people on hemodialysis and to assess risk factors associated with falls by synthesizing emerging best evidence.Methods A comprehensive search was conducted across ten databases from their inception to February 27, 2025. The research team independently conducted study selection, quality assessments, data extraction, and analyses of all included studies. Meta-analysis was performed using random-effects and fixed-effects models. The PRISMA guidelines were used to report the systematic review and meta-analysis.Results A total of 31 studies, comprising 191,800 individuals, were included in the analysis. The pooled prevalence of falls in people on hemodialysis was 27.1%. The meta-analysis of risk factors included 19 studies. After controlling for confounding variables, 12 risk factors were associated with falls, including older age, female gender, longer dialysis duration, diabetes mellitus, peripheral vascular disease, paralysis, antidepressant use, frailty, use of walking aids, malnutrition, intradialytic hypotension, and low hemoglobin levels.Conclusions This study provides an updated, evidence-based assessment of the prevalence and risk factors of falls in people on hemodialysis, confirming their multifactorial etiology. Screening and interventions should be implemented promptly to mitigate the adverse outcomes of falls in people on hemodialysis.Registration number PROSPERO CRD42024525375.https://www.tandfonline.com/doi/10.1080/0886022X.2025.2485375Accidental fallshemodialysisrisk factorsprevalencemeta-analysis
spellingShingle Jiayi Tang
Bei Wang
Qin Yuan
Xiaobo Li
Prevalence and risk factors of falls in people on hemodialysis: a systematic review and meta-analysis
Renal Failure
Accidental falls
hemodialysis
risk factors
prevalence
meta-analysis
title Prevalence and risk factors of falls in people on hemodialysis: a systematic review and meta-analysis
title_full Prevalence and risk factors of falls in people on hemodialysis: a systematic review and meta-analysis
title_fullStr Prevalence and risk factors of falls in people on hemodialysis: a systematic review and meta-analysis
title_full_unstemmed Prevalence and risk factors of falls in people on hemodialysis: a systematic review and meta-analysis
title_short Prevalence and risk factors of falls in people on hemodialysis: a systematic review and meta-analysis
title_sort prevalence and risk factors of falls in people on hemodialysis a systematic review and meta analysis
topic Accidental falls
hemodialysis
risk factors
prevalence
meta-analysis
url https://www.tandfonline.com/doi/10.1080/0886022X.2025.2485375
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AT beiwang prevalenceandriskfactorsoffallsinpeopleonhemodialysisasystematicreviewandmetaanalysis
AT qinyuan prevalenceandriskfactorsoffallsinpeopleonhemodialysisasystematicreviewandmetaanalysis
AT xiaoboli prevalenceandriskfactorsoffallsinpeopleonhemodialysisasystematicreviewandmetaanalysis