Engineering biotic stress tolerance via CRISPR-Cas mediated genome editing in crop plants

Plants are incessantly challenged by a plethora of plant pests and pathogens, putting global agricultural productivity and food security at stake. Over several decades, various strategies have been developed in agriculture to overcome plant diseases and insect pests. With chemical control that remai...

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Main Authors: Amjad Hussain, Mamoona Munir, Awais Khalid, Musrat Ali, Mohammed Amanullah, Qurban Ali, Hakim Manghwar
Format: Article
Language:English
Published: Elsevier 2024-12-01
Series:Plant Stress
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2667064X24003038
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author Amjad Hussain
Mamoona Munir
Awais Khalid
Musrat Ali
Mohammed Amanullah
Qurban Ali
Hakim Manghwar
author_facet Amjad Hussain
Mamoona Munir
Awais Khalid
Musrat Ali
Mohammed Amanullah
Qurban Ali
Hakim Manghwar
author_sort Amjad Hussain
collection DOAJ
description Plants are incessantly challenged by a plethora of plant pests and pathogens, putting global agricultural productivity and food security at stake. Over several decades, various strategies have been developed in agriculture to overcome plant diseases and insect pests. With chemical control that remains effective but involves severe ecological and environmental concerns, conventional and transgenic breeding strategies have been primarily deployed to generate new varieties with novel genetic mutations. Though these strategies present a pivotal role in plant development, in part, they normally include extensive and labor-intensive processes. CRISPR-Cas technology, a genome editing tool, has opened new avenues to accelerate plant breeding by creating disease and pest resistance in a wide range of plants. CRISPR-Cas revolutionized agriculture by limiting yield losses due to biotic stress and minimizing reliance on pesticide usage. Here, we summarize the advances of CRISPR-Cas technology and the applications of this technology in disease and pest resistance development in crop plants. In addition, the review also discusses the advantages and concerns of CRISPR-Cas genome editing in crop plants.
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issn 2667-064X
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series Plant Stress
spelling doaj-art-dd3044b3c4e247e9836d5e1801360aa62025-08-20T02:52:08ZengElsevierPlant Stress2667-064X2024-12-011410065010.1016/j.stress.2024.100650Engineering biotic stress tolerance via CRISPR-Cas mediated genome editing in crop plantsAmjad Hussain0Mamoona Munir1Awais Khalid2Musrat Ali3Mohammed Amanullah4Qurban Ali5Hakim Manghwar6Department of Biology, College of Science, United Arab Emirates University, Al-Ain, Abu-Dhabi, UAE; Hubei Hongshan Laboratory, National Key Laboratory of Crop Genetic Improvement, Huazhong Agricultural University, Wuhan 430070, ChinaDepartment of Botany, Rawalpindi Women University, Rawalpindi, PakistanDepartment of Physics, College of Science and Humanities in Al-Kharj, Prince Sattam bin Abdulaziz University, Al-Kharj 11942, Saudi ArabiaDepartment of Plant Pathology, Faculty of Crop Protection, Sindh Agricultural University, Tandojam, PakistanDepartment of Clinical Biochemistry, College of Medicine, King Khalid University, Abha, Saudi ArabiaDepartment of Biology, College of Science, United Arab Emirates University, Al-Ain, Abu-Dhabi, UAE; Corresponding authors.Lushan Botanical Garden Jiangxi Province and Chinese Academy of Sciences, Jiujiang, Jiangxi 332900, China; Corresponding authors.Plants are incessantly challenged by a plethora of plant pests and pathogens, putting global agricultural productivity and food security at stake. Over several decades, various strategies have been developed in agriculture to overcome plant diseases and insect pests. With chemical control that remains effective but involves severe ecological and environmental concerns, conventional and transgenic breeding strategies have been primarily deployed to generate new varieties with novel genetic mutations. Though these strategies present a pivotal role in plant development, in part, they normally include extensive and labor-intensive processes. CRISPR-Cas technology, a genome editing tool, has opened new avenues to accelerate plant breeding by creating disease and pest resistance in a wide range of plants. CRISPR-Cas revolutionized agriculture by limiting yield losses due to biotic stress and minimizing reliance on pesticide usage. Here, we summarize the advances of CRISPR-Cas technology and the applications of this technology in disease and pest resistance development in crop plants. In addition, the review also discusses the advantages and concerns of CRISPR-Cas genome editing in crop plants.http://www.sciencedirect.com/science/article/pii/S2667064X24003038Genome editingCRISPR-CasDisease resistanceInsect resistanceBase editingPrime editing
spellingShingle Amjad Hussain
Mamoona Munir
Awais Khalid
Musrat Ali
Mohammed Amanullah
Qurban Ali
Hakim Manghwar
Engineering biotic stress tolerance via CRISPR-Cas mediated genome editing in crop plants
Plant Stress
Genome editing
CRISPR-Cas
Disease resistance
Insect resistance
Base editing
Prime editing
title Engineering biotic stress tolerance via CRISPR-Cas mediated genome editing in crop plants
title_full Engineering biotic stress tolerance via CRISPR-Cas mediated genome editing in crop plants
title_fullStr Engineering biotic stress tolerance via CRISPR-Cas mediated genome editing in crop plants
title_full_unstemmed Engineering biotic stress tolerance via CRISPR-Cas mediated genome editing in crop plants
title_short Engineering biotic stress tolerance via CRISPR-Cas mediated genome editing in crop plants
title_sort engineering biotic stress tolerance via crispr cas mediated genome editing in crop plants
topic Genome editing
CRISPR-Cas
Disease resistance
Insect resistance
Base editing
Prime editing
url http://www.sciencedirect.com/science/article/pii/S2667064X24003038
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