Deoxyribonucleic acid methylation in the enhancer region of the CDKN2A/2B and CDKN2B-AS1 genes in blood vessels and cells in patients with carotid atherosclerosis

Deoxyribonucleic acid methylation in the enhancer region of the CDKN2A/2B and CDKN2B-AS1 genes in blood vessels and cells in patients with carotid atherosclerosis

Aim. Comparative analysis of the deoxyribonucleic acid (DNA) methylation level in the enhancer region of the CDKN2A/2B and CDKN2B-AS1 genes (9p21.3 locus) in vessels with/without atherosclerotic lesions, as well as in leukocytes of patients with clinically relevant carotid artery (CA) atherosclerosi...

Full description

Saved in:

Bibliographic Details
Main Authors:	Yu. A. Koroleva, A. V. Markov, I. A. Goncharova, A. A. Sleptsov, N. P. Babushkina, N. R. Valiakhmetov, D. V. Sharysh, A. A. Zarubin, M. S. Kuznetsov, B. N. Kozlov, M. S. Nazarenko
Format:	Article
Language:	Russian
Published:	«FIRMA «SILICEA» LLC 2020-11-01
Series:	Российский кардиологический журнал
Subjects:	atherosclerosis dna methylation 9p21.3 cdkn2a/2b cdkn2b-as1
Online Access:	https://russjcardiol.elpub.ru/jour/article/view/4060
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Case report: The smallest 9p21.3 microdeletion involving CDKN2A but not CDKN2B causes multiple plexiform neurofibromas
by: Yuanyuan Zhang, et al.
Published: (2025-02-01)

Association of CDKN2A/B deletions with survival of patients with diffuse large B-cell lymphoma
by: M. V. Sarpova, et al.
Published: (2024-01-01)

Clinical characteristics and prognostic analysis of CDKN2A/2B gene in pediatric acute lymphoblastic leukemia: a retrospective case-control study
by: Shi-Mei Huang, et al.
Published: (2025-12-01)

Frequency and Prognostic Impact of CDKN2A/B Alteration in Oligodendrogliomas: Systematic Review and Meta-analysis
by: Satoshi NAKASU, et al.
Published: (2024-12-01)

CDKN2A Mutation: A Patient’s and Physician’s Experience
by: Yaelle Shaked, et al.
Published: (2025-02-01)

A comprehensive consolidation of data on the connection between CDKN2A polymorphisms and the susceptibility to childhood acute lymphoblastic leukemia
by: Maryam Aghasipour, et al.
Published: (2024-12-01)

Retinoic acid inhibition of cell proliferation via activation of CDKN1B signaling in the forebrain and spinal cord during mouse embryonic development
by: Ahmed Said, et al.
Published: (2024-11-01)

Assessment of CDKN2A homozygous and heterozygous deletions in gliomas across multiple detection platforms
by: Hainan Li, et al.
Published: (2025-06-01)

Homozygous CDKN2A/B deletions in low- and high-grade glioma: a meta-analysis of individual patient data and predictive values of p16 immunohistochemistry testing
by: Darius Noack, et al.
Published: (2024-11-01)

Prevalence and prognostic impact of BRAF V600E mutation and CDKN2A deletion in pediatric high-grade glioma
by: Soha Karim, et al.
Published: (2025-08-01)

A case of hereditary CDKN2A p14ARF melanoma and dysplastic nevi
by: Jeremy K. Bray, MD, et al.
Published: (2025-07-01)

Network pharmacological approach combined with weighted gene co-expression network analysis identifies CDKN2A as the keg target of Changweiqing against colorectal cancer
by: Ma Zushuai, et al.
Published: (2025-03-01)

The Potential Association of CDKN2A and Ki-67 Proteins in View of the Selected Characteristics of Patients with Head and Neck Squamous Cell Carcinoma
by: Dariusz Nałęcz, et al.
Published: (2024-11-01)

CDKN2AIP-induced cell senescence and apoptosis of testicular seminoma are associated with CARM1 and eIF4β
by: Cao Yuming, et al.
Published: (2022-05-01)

Psychological Distress and Quality of Life in Families With a Germline CDKN2A Pathogenic Variant
by: A. M. Onnekink, et al.
Published: (2025-02-01)

Effect of the Ethanolic Extract of Eryngium billardieri on the Viability of the Triple-Negative Breast Cancer Cell Line (MDA-MB-231) and CDKN2A, MDM2, and HER2 Expression
by: Azadeh Hekmat, et al.
Published: (2024-12-01)

Case Report: FGFR2 inhibitor resistance via PIK3CA and CDKN2A/B in an intrahepatic cholangiocarcinoma patient with FGFR2-SH3GLB1 fusion
by: Nadja Ballin, et al.
Published: (2025-04-01)

Challenging CDKN2A assessment in BRAF-altered gliomas: lessons from a pleomorphic xanthoastrocytoma-enriched cohort
by: Thibaut Wolf, et al.
Published: (2025-08-01)

Expression of lncRNA CDKN2BAS in oral squamous cell carcinoma and its significance on cell proliferation and invasion
by: JIANG Shengjun, et al.
Published: (2023-08-01)

CDKN2A/p16INK4a DELETION IS NOT A POOR PROGNOSTIC FACTOR IN ADULT ACUTE LYMPHOBLASTIC LEUKEMIA PATIENTS TREATED ACCORDING TO PROTOCOL RALL-2009
by: I. S. Piskunova, et al.
Published: (2017-10-01)

Cdkn1a silencing restores myoblast differentiation by inducing selective apoptosis in senescent cells
by: Sujin Kim, et al.
Published: (2025-04-01)

<i>CDKN2A</i> Homozygous Deletion Is a Stronger Predictor of Outcome than <i>IDH1/2</i>-Mutation in CNS WHO Grade 4 Gliomas
by: Sang Hyuk Lee, et al.
Published: (2024-10-01)

Combination therapy of adagrasib and abemaciclib in non-small cell lung cancer brain metastasis models genomically characterized by KRAS-G12C and homozygous loss of CDKN2A
by: Christian Migliarese, et al.
Published: (2025-05-01)

LINC01094 promotes gastric cancer through dual targeting of CDKN1A by directly binding RBMS2 and HDAC1
by: Xinyi Zhou, et al.
Published: (2024-12-01)

p27<sup>Kip1</sup> and Tumors: Characterization of <i>CDKN1B</i> Variants Identified in MEN4 and Breast Cancer
by: Debora Bencivenga, et al.
Published: (2025-01-01)

Hereditary oral squamous cell carcinoma associated with CDKN2A germline mutation: a case report
by: Ah-Reum Jeong, et al.
Published: (2022-02-01)

Loss of Cdkn1a protects against MASLD alone or with alcohol intake by preserving lipid homeostasis
by: Arantza Lamas-Paz, et al.
Published: (2025-01-01)

The systematic analysis of genes related to butyrate metabolism suggests that CDKN3 could serve as a promising therapeutic target for lung adenocarcinoma treatment
by: Yanchao Luan, et al.
Published: (2025-01-01)

Causal relationship of familial hypercholesterolemia with risk of intestinal vascular disorders: A mendelian randomization study
by: Gang Wei, et al.
Published: (2025-03-01)

The Effect of CDKN1A on the Expression of Genes Related to Milk Protein and Milk Fat Synthesis in Bovine Mammary Epithelial Cells
by: Yuanyuan Zhang, et al.
Published: (2025-06-01)

Transcriptionally up-regulation of CDKN1A/p21 by TFE3 fusion proteins worsened TFE3-rearranged renal cell carcinoma
by: Yanwen Lu, et al.
Published: (2025-08-01)

The role of complete exomic sequencing in the administration of targeted drugs in patients with multiform glioblastoma
by: A. V. Kaminskiy, et al.
Published: (2023-06-01)

A systematic literature review of MTAP deletions in solid and hematologic Cancers
by: Mary C. Clouser, et al.
Published: (2025-01-01)

A CDKN2B-Associated Immune Prognostic Model for Predicting Immune Cell Infiltration and Prognosis in Esophageal Carcinoma
by: Peng X, et al.
Published: (2025-04-01)

The differences of B2C and B2B workflow exception handling
by: Dovilė Vojevodina, et al.
Published: (2005-12-01)

The important role of cuproptosis and cuproptosis-related genes in the development of thyroid carcinoma revealed by transcriptomic analysis and experiments
by: Yani Liu, et al.
Published: (2025-05-01)

mRNA-lncRNA gene expression signature in HPV-associated neoplasia and cervical cancer
by: E. D. Kulaeva, et al.
Published: (2024-05-01)

Increased MLH1, MGMT, and p16INK4a methylation levels in colon mucosa potentially useful as early risk marker of colon cancer
by: Yvonne Wettergren, et al.
Published: (2025-12-01)

Integrated real-time precise point positioning system with B2b/B2a/B1C services
by: Zhetao Zhang, et al.
Published: (2025-07-01)

Analysis of genetic aberrations in pediatric high-grade gliomas
by: M. A. Zaytseva, et al.
Published: (2020-11-01)