Can carbamide peroxide be as effective as hydrogen peroxide for in-office tooth bleaching and cause less sensitivity? A systematic review

This study aimed to answer the question through a systematic review: Can carbamide peroxide be as effective as hydrogen peroxide and cause less in-office bleaching sensitivity? A literature survey was performed in PubMed/MEDLINE, Embase, Scopus, ISI Web of Science, and gray literature. Primary clini...

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Main Authors: Patrick Wesley Marques de Boa, Kaiza de Sousa Santos, Francisca Jennifer Duarte de Oliveira, Boniek Castillo Dutra Borges
Format: Article
Language:English
Published: Korean Academy of Conservative Dentistry 2024-05-01
Series:Restorative Dentistry & Endodontics
Subjects:
Online Access:http://www.rde.ac/upload/pdf/rde-49-e14.pdf
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author Patrick Wesley Marques de Boa
Kaiza de Sousa Santos
Francisca Jennifer Duarte de Oliveira
Boniek Castillo Dutra Borges
author_facet Patrick Wesley Marques de Boa
Kaiza de Sousa Santos
Francisca Jennifer Duarte de Oliveira
Boniek Castillo Dutra Borges
author_sort Patrick Wesley Marques de Boa
collection DOAJ
description This study aimed to answer the question through a systematic review: Can carbamide peroxide be as effective as hydrogen peroxide and cause less in-office bleaching sensitivity? A literature survey was performed in PubMed/MEDLINE, Embase, Scopus, ISI Web of Science, and gray literature. Primary clinical trials that compared the efficacy or the in-office bleaching sensitivity between carbamide and hydrogen peroxides were included. The risk of bias was evaluated using the RoB2. The certainty of the evidence was assessed using the GRADE approach. DPI training significantly improved the mean scores of the dental undergraduates from 7.53 in the pre-DPI-training test to 9.01 in the post-DPI-training test (p < 0.001). After 6 weeks, the mean scores decreased marginally to 8.87 in the retention test (p = 0.563). DPI training increased their confidence level from 5.68 pre-DPI training to 7.09 post-DPI training. The limited evidence suggests that the 37% carbamide peroxide may be similarly effective to the 35% hydrogen peroxide for bleaching teeth in-office and causes less bleaching sensitivity. However, more well-designed split-mouth clinical trials are necessary to strengthen the evidence.
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institution Kabale University
issn 2234-7658
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language English
publishDate 2024-05-01
publisher Korean Academy of Conservative Dentistry
record_format Article
series Restorative Dentistry & Endodontics
spelling doaj-art-dd29b02afbde43dbb4a594f09be484612025-08-20T03:29:18ZengKorean Academy of Conservative DentistryRestorative Dentistry & Endodontics2234-76582234-76662024-05-01492e1410.5395/rde.2024.49.e141096Can carbamide peroxide be as effective as hydrogen peroxide for in-office tooth bleaching and cause less sensitivity? A systematic reviewPatrick Wesley Marques de BoaKaiza de Sousa SantosFrancisca Jennifer Duarte de OliveiraBoniek Castillo Dutra BorgesThis study aimed to answer the question through a systematic review: Can carbamide peroxide be as effective as hydrogen peroxide and cause less in-office bleaching sensitivity? A literature survey was performed in PubMed/MEDLINE, Embase, Scopus, ISI Web of Science, and gray literature. Primary clinical trials that compared the efficacy or the in-office bleaching sensitivity between carbamide and hydrogen peroxides were included. The risk of bias was evaluated using the RoB2. The certainty of the evidence was assessed using the GRADE approach. DPI training significantly improved the mean scores of the dental undergraduates from 7.53 in the pre-DPI-training test to 9.01 in the post-DPI-training test (p < 0.001). After 6 weeks, the mean scores decreased marginally to 8.87 in the retention test (p = 0.563). DPI training increased their confidence level from 5.68 pre-DPI training to 7.09 post-DPI training. The limited evidence suggests that the 37% carbamide peroxide may be similarly effective to the 35% hydrogen peroxide for bleaching teeth in-office and causes less bleaching sensitivity. However, more well-designed split-mouth clinical trials are necessary to strengthen the evidence.http://www.rde.ac/upload/pdf/rde-49-e14.pdfcarbamide peroxidesystematic reviewtooth bleachingzydrogen peroxide
spellingShingle Patrick Wesley Marques de Boa
Kaiza de Sousa Santos
Francisca Jennifer Duarte de Oliveira
Boniek Castillo Dutra Borges
Can carbamide peroxide be as effective as hydrogen peroxide for in-office tooth bleaching and cause less sensitivity? A systematic review
Restorative Dentistry & Endodontics
carbamide peroxide
systematic review
tooth bleaching
zydrogen peroxide
title Can carbamide peroxide be as effective as hydrogen peroxide for in-office tooth bleaching and cause less sensitivity? A systematic review
title_full Can carbamide peroxide be as effective as hydrogen peroxide for in-office tooth bleaching and cause less sensitivity? A systematic review
title_fullStr Can carbamide peroxide be as effective as hydrogen peroxide for in-office tooth bleaching and cause less sensitivity? A systematic review
title_full_unstemmed Can carbamide peroxide be as effective as hydrogen peroxide for in-office tooth bleaching and cause less sensitivity? A systematic review
title_short Can carbamide peroxide be as effective as hydrogen peroxide for in-office tooth bleaching and cause less sensitivity? A systematic review
title_sort can carbamide peroxide be as effective as hydrogen peroxide for in office tooth bleaching and cause less sensitivity a systematic review
topic carbamide peroxide
systematic review
tooth bleaching
zydrogen peroxide
url http://www.rde.ac/upload/pdf/rde-49-e14.pdf
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