Impact of life adversity and gene expression on psychiatric symptoms in children and adolescents: findings from the Brazilian high risk cohort study

Impact of life adversity and gene expression on psychiatric symptoms in children and adolescents: findings from the Brazilian high risk cohort study

IntroductionWhile the influence of both genetic and environmental factors on the development of psychiatric symptoms is well-recognized, the precise nature of their interaction throughout development remains a subject of ongoing debate. This study investigated the association between the expression...

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Main Authors: Vanessa Kiyomi Ota, Adrielle Martins Oliveira, Amanda Victória Gomes Bugiga, Helena B. Conceição, Pedro Alexandre Favoretto Galante, Paula Fontes Asprino, Julia Luiza Schäfer, Mauricio Scopel Hoffmann, Rodrigo Bressan, Elisa Brietzke, Gisele Gus Manfro, Rodrigo Grassi-Oliveira, Ary Gadelha, Luis Augusto Rohde, Euripedes Constantino Miguel, Pedro Mario Pan, Marcos Leite Santoro, Giovanni Abrahao Salum, Carolina Muniz Carvalho, Sintia Iole Belangero
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Psychiatry
Subjects:
psychopathology
transcriptome
internalizing symptoms
externalizing symptoms
genetics
trauma
Online Access:https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1505421/full
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