LONG-TERM OUTCOMES IN RHEUMATOID ARTHRITIS IN RELATION TO THE TIME AFTER THE INITIATIONOF BASIC ANTI-INFLAMMATORY DRUG THERAPY
The paper presents the long-term outcomes of rheumatoid arthritis (RA) according to the data of a 15-year prospective follow-up and treatment in 240 patients with the disease. Disease activity resistance (stable remission of more than 2 years, a recurring course with druginduced remissions of 6-18 m...
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| Format: | Article |
| Language: | Russian |
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IMA PRESS LLC
2010-06-01
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| Series: | Научно-практическая ревматология |
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| Online Access: | https://rsp.mediar-press.net/rsp/article/view/577 |
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| author | Natalya Vladimirovna Chichasova M Z Kanevskaya G R Imametdinova E V Igolkina E L Nasonov |
| author_facet | Natalya Vladimirovna Chichasova M Z Kanevskaya G R Imametdinova E V Igolkina E L Nasonov |
| author_sort | Natalya Vladimirovna Chichasova |
| collection | DOAJ |
| description | The paper presents the long-term outcomes of rheumatoid arthritis (RA) according to the data of a 15-year prospective follow-up and treatment in 240 patients with the disease. Disease activity resistance (stable remission of more than 2 years, a recurring course with druginduced remissions of 6-18 months, or no remissions), the degree of joint destruction progression, the functional state of patients and their survival were assessed in relation to the time of use of basic anti-inflammatory drugs (BAIDs). In groups 1, 2, and 3, BAID therapy was initiated within the first 5 months of RA, 6-11 and 12-36 months after its onset, respectively. The treatment was monitored, by estimating clinical and X-ray parameters, the functional state of the locomotor apparatus and by correcting the therapy at its stages in the absence of reliable suppression of RA activity and/or with the continuing emergence of new erosions in small joints. The early use of BAIDs under meticulous control of the degree of RA activity suppression and RA progression were shown to frequently achieve clinical and laboratory remissions and to improve functional and life prognosis in the patients. |
| format | Article |
| id | doaj-art-dd1b38f03af94b61ace27fb9e0145daa |
| institution | DOAJ |
| issn | 1995-4484 1995-4492 |
| language | Russian |
| publishDate | 2010-06-01 |
| publisher | IMA PRESS LLC |
| record_format | Article |
| series | Научно-практическая ревматология |
| spelling | doaj-art-dd1b38f03af94b61ace27fb9e0145daa2025-08-20T03:21:47ZrusIMA PRESS LLCНаучно-практическая ревматология1995-44841995-44922010-06-01483233010.14412/1995-4484-2010-439517LONG-TERM OUTCOMES IN RHEUMATOID ARTHRITIS IN RELATION TO THE TIME AFTER THE INITIATIONOF BASIC ANTI-INFLAMMATORY DRUG THERAPYNatalya Vladimirovna ChichasovaM Z KanevskayaG R ImametdinovaE V IgolkinaE L NasonovThe paper presents the long-term outcomes of rheumatoid arthritis (RA) according to the data of a 15-year prospective follow-up and treatment in 240 patients with the disease. Disease activity resistance (stable remission of more than 2 years, a recurring course with druginduced remissions of 6-18 months, or no remissions), the degree of joint destruction progression, the functional state of patients and their survival were assessed in relation to the time of use of basic anti-inflammatory drugs (BAIDs). In groups 1, 2, and 3, BAID therapy was initiated within the first 5 months of RA, 6-11 and 12-36 months after its onset, respectively. The treatment was monitored, by estimating clinical and X-ray parameters, the functional state of the locomotor apparatus and by correcting the therapy at its stages in the absence of reliable suppression of RA activity and/or with the continuing emergence of new erosions in small joints. The early use of BAIDs under meticulous control of the degree of RA activity suppression and RA progression were shown to frequently achieve clinical and laboratory remissions and to improve functional and life prognosis in the patients.https://rsp.mediar-press.net/rsp/article/view/577rheumatoid arthritisbasic anti-inflammatory drugsremissionmonitoring |
| spellingShingle | Natalya Vladimirovna Chichasova M Z Kanevskaya G R Imametdinova E V Igolkina E L Nasonov LONG-TERM OUTCOMES IN RHEUMATOID ARTHRITIS IN RELATION TO THE TIME AFTER THE INITIATIONOF BASIC ANTI-INFLAMMATORY DRUG THERAPY Научно-практическая ревматология rheumatoid arthritis basic anti-inflammatory drugs remission monitoring |
| title | LONG-TERM OUTCOMES IN RHEUMATOID ARTHRITIS IN RELATION TO THE TIME AFTER THE INITIATIONOF BASIC ANTI-INFLAMMATORY DRUG THERAPY |
| title_full | LONG-TERM OUTCOMES IN RHEUMATOID ARTHRITIS IN RELATION TO THE TIME AFTER THE INITIATIONOF BASIC ANTI-INFLAMMATORY DRUG THERAPY |
| title_fullStr | LONG-TERM OUTCOMES IN RHEUMATOID ARTHRITIS IN RELATION TO THE TIME AFTER THE INITIATIONOF BASIC ANTI-INFLAMMATORY DRUG THERAPY |
| title_full_unstemmed | LONG-TERM OUTCOMES IN RHEUMATOID ARTHRITIS IN RELATION TO THE TIME AFTER THE INITIATIONOF BASIC ANTI-INFLAMMATORY DRUG THERAPY |
| title_short | LONG-TERM OUTCOMES IN RHEUMATOID ARTHRITIS IN RELATION TO THE TIME AFTER THE INITIATIONOF BASIC ANTI-INFLAMMATORY DRUG THERAPY |
| title_sort | long term outcomes in rheumatoid arthritis in relation to the time after the initiationof basic anti inflammatory drug therapy |
| topic | rheumatoid arthritis basic anti-inflammatory drugs remission monitoring |
| url | https://rsp.mediar-press.net/rsp/article/view/577 |
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