A `glue sniffer` teenager with anuric renal failure and hepatitis
`Inhalant abuse` is a common form of volatile drug abuse throughout the world especially in developing countries. This substance mainly contains toluene. Acute toluene inhalation produces a biphasic response with an initial central nervous system (CNS) excitation followed by CNS depression as well...
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| Format: | Article |
| Language: | English |
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Hacettepe University Institute of Child Health
2018-04-01
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| Series: | The Turkish Journal of Pediatrics |
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| Online Access: | https://turkjpediatr.org/article/view/842 |
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| author | Ali Yurtseven Mümine Türksoylu Pınar Yazıcı Bülent Karapınar Eylem Ulaş Saz |
| author_facet | Ali Yurtseven Mümine Türksoylu Pınar Yazıcı Bülent Karapınar Eylem Ulaş Saz |
| author_sort | Ali Yurtseven |
| collection | DOAJ |
| description |
`Inhalant abuse` is a common form of volatile drug abuse throughout the world especially in developing countries. This substance mainly contains toluene. Acute toluene inhalation produces a biphasic response with an initial central nervous system (CNS) excitation followed by CNS depression as well as various metabolic alterations. Chronic inhalational abuse is associated with muscular weakness, gastrointestinal symptoms, renal and hepatic injury. In this report, a 16-year-old boy presented with jaundice, nausea, vomiting and reduced urine output. He developed severe acute renal/hepatic damage due to abuse of gas products. Since toluene is the main toxic agent involved in glue sniffing which is metabolized to hippuric acid, the present case was treated with continuous hemodiafiltration, plasma exchange and conservative therapy to eliminate hippuric acid. The jaundice gradually disappeared, he had complete recovery of renal/hepatic functions in ten days. We aimed to increase the awareness among emergency physicians that ``glue sniffing` should be considered in the differential diagnosis of unexplained reversible acute renal/hepatic damage.
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| format | Article |
| id | doaj-art-dd12057ca7fe4149b2f91565f0d8ac44 |
| institution | DOAJ |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2018-04-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-dd12057ca7fe4149b2f91565f0d8ac442025-08-20T02:55:38ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212018-04-0160210.24953/turkjped.2018.02.016A `glue sniffer` teenager with anuric renal failure and hepatitisAli YurtsevenMümine Türksoylu0Pınar Yazıcı1Bülent Karapınar2Eylem Ulaş SazDivision of Emergency Medicine, Ege University School of Medicine, İzmir, Turkey.Department of Pediatrics, Ege University School of Medicine, İzmir, Turkey.Department of Pediatrics, Ege University School of Medicine, İzmir, Turkey. `Inhalant abuse` is a common form of volatile drug abuse throughout the world especially in developing countries. This substance mainly contains toluene. Acute toluene inhalation produces a biphasic response with an initial central nervous system (CNS) excitation followed by CNS depression as well as various metabolic alterations. Chronic inhalational abuse is associated with muscular weakness, gastrointestinal symptoms, renal and hepatic injury. In this report, a 16-year-old boy presented with jaundice, nausea, vomiting and reduced urine output. He developed severe acute renal/hepatic damage due to abuse of gas products. Since toluene is the main toxic agent involved in glue sniffing which is metabolized to hippuric acid, the present case was treated with continuous hemodiafiltration, plasma exchange and conservative therapy to eliminate hippuric acid. The jaundice gradually disappeared, he had complete recovery of renal/hepatic functions in ten days. We aimed to increase the awareness among emergency physicians that ``glue sniffing` should be considered in the differential diagnosis of unexplained reversible acute renal/hepatic damage. https://turkjpediatr.org/article/view/842acute kidney injuryglue sniffinghepatitisjaundice |
| spellingShingle | Ali Yurtseven Mümine Türksoylu Pınar Yazıcı Bülent Karapınar Eylem Ulaş Saz A `glue sniffer` teenager with anuric renal failure and hepatitis The Turkish Journal of Pediatrics acute kidney injury glue sniffing hepatitis jaundice |
| title | A `glue sniffer` teenager with anuric renal failure and hepatitis |
| title_full | A `glue sniffer` teenager with anuric renal failure and hepatitis |
| title_fullStr | A `glue sniffer` teenager with anuric renal failure and hepatitis |
| title_full_unstemmed | A `glue sniffer` teenager with anuric renal failure and hepatitis |
| title_short | A `glue sniffer` teenager with anuric renal failure and hepatitis |
| title_sort | glue sniffer teenager with anuric renal failure and hepatitis |
| topic | acute kidney injury glue sniffing hepatitis jaundice |
| url | https://turkjpediatr.org/article/view/842 |
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