Successful Surgical Removal of the Largest Known Spleen
Background. Splenic marginal zone lymphoma (SMZL) is a rare subtype of non-Hodgkin lymphoma that typically presents with symptomatic splenomegaly. The optimal treatment of SMZL not well established. Case Presentation. A 44-year-old man with a history of low-grade B-cell lymphoproliferative disorder...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2020/6790808 |
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| author | David J. Hall Nam H. Dang Christiana M. Shaw |
| author_facet | David J. Hall Nam H. Dang Christiana M. Shaw |
| author_sort | David J. Hall |
| collection | DOAJ |
| description | Background. Splenic marginal zone lymphoma (SMZL) is a rare subtype of non-Hodgkin lymphoma that typically presents with symptomatic splenomegaly. The optimal treatment of SMZL not well established. Case Presentation. A 44-year-old man with a history of low-grade B-cell lymphoproliferative disorder previously treated with chemotherapy presented with a three-month history of rapidly enlarging abdominal girth. He was found to have large symptomatic splenomegaly by computed tomography. After workup, he underwent preoperative angioembolization of the splenic artery followed by successful splenectomy. The spleen measured 45 cm in greatest dimension and weighed 12.14 kg, more than 12% of the patient’s total body weight, making this both the largest spleen on record as well as the largest spleen ever surgically removed. Pathology was consistent with splenic marginal zone lymphoma. The patient did well and was discharged home on postoperative day 3. Conclusions. SMZL is an infrequent condition that leads to progressive symptomatic splenomegaly which can be managed surgically providing symptomatic improvement and an overall satisfactory oncologic outcome. A multidisciplinary approach to complex cases of SMZL splenomegaly is imperative to achieving optimal outcomes. |
| format | Article |
| id | doaj-art-dd0c519eecbf439caafa73bcd07e7ef7 |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-dd0c519eecbf439caafa73bcd07e7ef72025-08-20T03:26:30ZengWileyCase Reports in Surgery2090-69002090-69192020-01-01202010.1155/2020/67908086790808Successful Surgical Removal of the Largest Known SpleenDavid J. Hall0Nam H. Dang1Christiana M. Shaw2Department of Surgery, University of Florida College of Medicine, USADivision of Hematology & Oncology, Department of Medicine, University of Florida College of Medicine, USADepartment of Surgery, University of Florida College of Medicine, USABackground. Splenic marginal zone lymphoma (SMZL) is a rare subtype of non-Hodgkin lymphoma that typically presents with symptomatic splenomegaly. The optimal treatment of SMZL not well established. Case Presentation. A 44-year-old man with a history of low-grade B-cell lymphoproliferative disorder previously treated with chemotherapy presented with a three-month history of rapidly enlarging abdominal girth. He was found to have large symptomatic splenomegaly by computed tomography. After workup, he underwent preoperative angioembolization of the splenic artery followed by successful splenectomy. The spleen measured 45 cm in greatest dimension and weighed 12.14 kg, more than 12% of the patient’s total body weight, making this both the largest spleen on record as well as the largest spleen ever surgically removed. Pathology was consistent with splenic marginal zone lymphoma. The patient did well and was discharged home on postoperative day 3. Conclusions. SMZL is an infrequent condition that leads to progressive symptomatic splenomegaly which can be managed surgically providing symptomatic improvement and an overall satisfactory oncologic outcome. A multidisciplinary approach to complex cases of SMZL splenomegaly is imperative to achieving optimal outcomes.http://dx.doi.org/10.1155/2020/6790808 |
| spellingShingle | David J. Hall Nam H. Dang Christiana M. Shaw Successful Surgical Removal of the Largest Known Spleen Case Reports in Surgery |
| title | Successful Surgical Removal of the Largest Known Spleen |
| title_full | Successful Surgical Removal of the Largest Known Spleen |
| title_fullStr | Successful Surgical Removal of the Largest Known Spleen |
| title_full_unstemmed | Successful Surgical Removal of the Largest Known Spleen |
| title_short | Successful Surgical Removal of the Largest Known Spleen |
| title_sort | successful surgical removal of the largest known spleen |
| url | http://dx.doi.org/10.1155/2020/6790808 |
| work_keys_str_mv | AT davidjhall successfulsurgicalremovalofthelargestknownspleen AT namhdang successfulsurgicalremovalofthelargestknownspleen AT christianamshaw successfulsurgicalremovalofthelargestknownspleen |