Association of SNPs in nAChRs genes, areca nut chewing and smoking, and their interaction with lung cancer in Hainan, China: a case control study

Association of SNPs in nAChRs genes, areca nut chewing and smoking, and their interaction with lung cancer in Hainan, China: a case control study

Abstract Background Areca nut (AN) was classified as a carcinogen by the International Agency for Research on Cancer (IARC) of the WHO in 2003. AN has the same carcinogenic components as cigarettes, such as benzo[a]pyrene (B[a]P) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), but its effe...

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Bibliographic Details
Main Authors: Yixuan Li, Jing Zhou, Lirong Liu, Chaoyong Zhu, Ziyue Luo, Na Li, Pengfei Lyu, Jing Zhang, Tian Xie, Yipeng Ding, Sha Xiao
Format: Article
Language:English
Published: BMC 2025-04-01
Series:BMC Cancer
Subjects:
Areca nut
Cigarette
nAChRs
SNP
Lung cancer
Online Access:https://doi.org/10.1186/s12885-025-14020-3
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