Arabic patient-reported outcome measures for xerostomia and oral mucositis: Translation and cross-cultural adaptation

Introduction: Xerostomia and oral mucositis (OM) are common oral complications of head-and-neck cancer (HNC) radiotherapy. Aims: This study aimed to translate and assess the key validity and reliability properties of the Summated Xerostomia Inventory (SXI) and the patient-reported OM symptom (PROMS)...

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Main Authors: Saif A. Aljabab, Bader A. Alwhaibi, Abdullah F. Alnuwaybit, Aljoud S. Algazlan, Rema S. Alkahtani, Yasir M. Alayed, Abdullah M. Alsogheir
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Saudi Journal of Oral Sciences
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Online Access:https://journals.lww.com/10.4103/sjoralsci.sjoralsci_9_25
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author Saif A. Aljabab
Bader A. Alwhaibi
Abdullah F. Alnuwaybit
Aljoud S. Algazlan
Rema S. Alkahtani
Yasir M. Alayed
Abdullah M. Alsogheir
author_facet Saif A. Aljabab
Bader A. Alwhaibi
Abdullah F. Alnuwaybit
Aljoud S. Algazlan
Rema S. Alkahtani
Yasir M. Alayed
Abdullah M. Alsogheir
author_sort Saif A. Aljabab
collection DOAJ
description Introduction: Xerostomia and oral mucositis (OM) are common oral complications of head-and-neck cancer (HNC) radiotherapy. Aims: This study aimed to translate and assess the key validity and reliability properties of the Summated Xerostomia Inventory (SXI) and the patient-reported OM symptom (PROMS) in the Arabic patient cohort. Materials and Methods: This observational study was conducted at King Saud University Medical City, Riyadh, Saudi Arabia. Six expert clinicians translated both instruments and assessed them for content validity. They then evaluated validity (face and construct validity) and reliability (internal consistency and test–retest reliability) with adult participants who received radiotherapy for HNC. Results and Discussion: Thirty-eight patients (males = 19, females = 19) were recruited with a mean age of 50 years (±16). The Arabic SXI (SXI-Ar) and Arabic PROMS (PROMS-Ar) were considered relevant, sufficient, and understandable. Furthermore, high internal consistency was demonstrated by SXI-Ar (α = 0.851) and PROMS-Ar (α = 0.957). However, there were moderate to poor agreements between both instruments’ 1st and 2nd-week completions, as shown by the average correlation coefficients of 0.407 and −0.364, respectively. It was also evident that both xerostomia and OM scores were significantly correlated (r = 0.372, P = 0.043). Conclusions: SXI-Ar and PROMS-Ar showed preliminary satisfactory measurement properties. Both instruments could be used in daily clinical consultations and clinician-reported assessments in oncology, nutritional, and maxillofacial care settings. However, further assessments of hypotheses testing, criterion validity, and responsiveness with a large patient cohort are needed.
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spelling doaj-art-dcf1c61214064bc3a6b477cb1c6c646e2025-08-20T02:27:40ZengWolters Kluwer Medknow PublicationsSaudi Journal of Oral Sciences2542-78492025-01-01121465110.4103/sjoralsci.sjoralsci_9_25Arabic patient-reported outcome measures for xerostomia and oral mucositis: Translation and cross-cultural adaptationSaif A. AljababBader A. AlwhaibiAbdullah F. AlnuwaybitAljoud S. AlgazlanRema S. AlkahtaniYasir M. AlayedAbdullah M. AlsogheirIntroduction: Xerostomia and oral mucositis (OM) are common oral complications of head-and-neck cancer (HNC) radiotherapy. Aims: This study aimed to translate and assess the key validity and reliability properties of the Summated Xerostomia Inventory (SXI) and the patient-reported OM symptom (PROMS) in the Arabic patient cohort. Materials and Methods: This observational study was conducted at King Saud University Medical City, Riyadh, Saudi Arabia. Six expert clinicians translated both instruments and assessed them for content validity. They then evaluated validity (face and construct validity) and reliability (internal consistency and test–retest reliability) with adult participants who received radiotherapy for HNC. Results and Discussion: Thirty-eight patients (males = 19, females = 19) were recruited with a mean age of 50 years (±16). The Arabic SXI (SXI-Ar) and Arabic PROMS (PROMS-Ar) were considered relevant, sufficient, and understandable. Furthermore, high internal consistency was demonstrated by SXI-Ar (α = 0.851) and PROMS-Ar (α = 0.957). However, there were moderate to poor agreements between both instruments’ 1st and 2nd-week completions, as shown by the average correlation coefficients of 0.407 and −0.364, respectively. It was also evident that both xerostomia and OM scores were significantly correlated (r = 0.372, P = 0.043). Conclusions: SXI-Ar and PROMS-Ar showed preliminary satisfactory measurement properties. Both instruments could be used in daily clinical consultations and clinician-reported assessments in oncology, nutritional, and maxillofacial care settings. However, further assessments of hypotheses testing, criterion validity, and responsiveness with a large patient cohort are needed.https://journals.lww.com/10.4103/sjoralsci.sjoralsci_9_25head-and-neck neoplasmsoral mucositispatient-reported outcome measurespsychometricsxerostomia
spellingShingle Saif A. Aljabab
Bader A. Alwhaibi
Abdullah F. Alnuwaybit
Aljoud S. Algazlan
Rema S. Alkahtani
Yasir M. Alayed
Abdullah M. Alsogheir
Arabic patient-reported outcome measures for xerostomia and oral mucositis: Translation and cross-cultural adaptation
Saudi Journal of Oral Sciences
head-and-neck neoplasms
oral mucositis
patient-reported outcome measures
psychometrics
xerostomia
title Arabic patient-reported outcome measures for xerostomia and oral mucositis: Translation and cross-cultural adaptation
title_full Arabic patient-reported outcome measures for xerostomia and oral mucositis: Translation and cross-cultural adaptation
title_fullStr Arabic patient-reported outcome measures for xerostomia and oral mucositis: Translation and cross-cultural adaptation
title_full_unstemmed Arabic patient-reported outcome measures for xerostomia and oral mucositis: Translation and cross-cultural adaptation
title_short Arabic patient-reported outcome measures for xerostomia and oral mucositis: Translation and cross-cultural adaptation
title_sort arabic patient reported outcome measures for xerostomia and oral mucositis translation and cross cultural adaptation
topic head-and-neck neoplasms
oral mucositis
patient-reported outcome measures
psychometrics
xerostomia
url https://journals.lww.com/10.4103/sjoralsci.sjoralsci_9_25
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