Resource utilization and economic outcomes following repetitive transcranial magnetic stimulation for treatment-resistant depression: a retrospective observational analysis
Aim: We investigated the impact of repetitive transcranial magnetic stimulation (rTMS) for treatmentresistant depression on healthcare resource utilization as well as commercial and Medicare Fee-for-Service payer costs. Materials & methods:We conducted a retrospective observational analysis of...
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Becaris Publishing Limited
2025-01-01
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| Series: | Journal of Comparative Effectiveness Research |
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| _version_ | 1849708185393299456 |
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| author | Joseph J Taylor Andrew J Manett Michael Feyder Brandon S Bentzley |
| author_facet | Joseph J Taylor Andrew J Manett Michael Feyder Brandon S Bentzley |
| author_sort | Joseph J Taylor |
| collection | DOAJ |
| description | Aim: We investigated the impact of repetitive transcranial magnetic stimulation (rTMS) for treatmentresistant
depression on healthcare resource utilization as well as commercial and Medicare Fee-for-Service
payer costs. Materials & methods:We conducted a retrospective observational analysis of claims data using
Medicare Fee-for-Service datasets and commercial (Merative MarketScan Research Databases) datasets
from 1 January 2021 to 30 September 2023. We identified two cohorts, a cohort that received rTMS and
a cohort not treated with rTMS over an 18-month period. We used propensity score matching to balance
the baseline characteristics of the cohorts, and we calculated the total cost of care based on payer allowed
amounts from Merative MarketScan Research Databases and Standard Analytical Files. Results: Relative
to the non-TMS cohort, the rTMS cohort incurred 37% more hospital outpatient visits (14.00 vs 10.21;
p ≤ 0.0001) with 7% higher outpatient cost ($8946 vs $8363; p = 0.3400). Simultaneously, the rTMS cohort
incurred 24% fewer inpatient admissions (0.25 vs 0.33; p = 0.0003) with 19% lower inpatient admission
costs ($5666 vs $6978; p = 0.0392), 48% fewer emergency room visits (0.27 vs 0.53; p ≤ 0.0001) with 34%
lower emergency room costs ($322 vs $487; p ≤ 0.0001), and $893 less in episode of care costs. Conclusion:
This study suggests that patientswho receive rTMS for treatment-resistant depression required fewer high
acuity hospital visits and incurred less expensive episode-of-care costs compared with patients who do not
receive rTMS. From this perspective, rTMS is an investment that returns health and economic dividends
through fewer high acuity hospital visits. |
| format | Article |
| id | doaj-art-dcf1640f1be34313ba75330c24abda11 |
| institution | DOAJ |
| issn | 2042-6313 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Becaris Publishing Limited |
| record_format | Article |
| series | Journal of Comparative Effectiveness Research |
| spelling | doaj-art-dcf1640f1be34313ba75330c24abda112025-08-20T03:15:44ZengBecaris Publishing LimitedJournal of Comparative Effectiveness Research2042-63132025-01-0114710.57264/cer-2025-0019Resource utilization and economic outcomes following repetitive transcranial magnetic stimulation for treatment-resistant depression: a retrospective observational analysisJoseph J Taylor0https://orcid.org/0000-0002-9185-0427Andrew J Manett1https://orcid.org/0000-0002-4065-8013Michael Feyder2https://orcid.org/0000-0001-5849-905XBrandon S Bentzley3Harvard Medical School, Boston, MA 02115, USA; Center for Brain Circuit Therapeutics, Department of Psychiatry, Mass General Brigham, Boston, MA 02115, USA; Department of Psychiatry, Mass General Brigham, Boston, MA 02115, USABrain Stimulation Service, Department of Psychiatry, Medical University of South Carolina, Charleston, SC 29425, USAMagnus Medical Inc., Burlingame, CA 94010, USAMagnus Medical Inc., Burlingame, CA 94010, USAAim: We investigated the impact of repetitive transcranial magnetic stimulation (rTMS) for treatmentresistant depression on healthcare resource utilization as well as commercial and Medicare Fee-for-Service payer costs. Materials & methods:We conducted a retrospective observational analysis of claims data using Medicare Fee-for-Service datasets and commercial (Merative MarketScan Research Databases) datasets from 1 January 2021 to 30 September 2023. We identified two cohorts, a cohort that received rTMS and a cohort not treated with rTMS over an 18-month period. We used propensity score matching to balance the baseline characteristics of the cohorts, and we calculated the total cost of care based on payer allowed amounts from Merative MarketScan Research Databases and Standard Analytical Files. Results: Relative to the non-TMS cohort, the rTMS cohort incurred 37% more hospital outpatient visits (14.00 vs 10.21; p ≤ 0.0001) with 7% higher outpatient cost ($8946 vs $8363; p = 0.3400). Simultaneously, the rTMS cohort incurred 24% fewer inpatient admissions (0.25 vs 0.33; p = 0.0003) with 19% lower inpatient admission costs ($5666 vs $6978; p = 0.0392), 48% fewer emergency room visits (0.27 vs 0.53; p ≤ 0.0001) with 34% lower emergency room costs ($322 vs $487; p ≤ 0.0001), and $893 less in episode of care costs. Conclusion: This study suggests that patientswho receive rTMS for treatment-resistant depression required fewer high acuity hospital visits and incurred less expensive episode-of-care costs compared with patients who do not receive rTMS. From this perspective, rTMS is an investment that returns health and economic dividends through fewer high acuity hospital visits.eoc costsepisode of care costshealthcare utilizationmajor depressive disordermddrepetitive transcranial magnetic stimulationrtmssaintsaint neuromodulation systemtrdtreatment-resistant depression |
| spellingShingle | Joseph J Taylor Andrew J Manett Michael Feyder Brandon S Bentzley Resource utilization and economic outcomes following repetitive transcranial magnetic stimulation for treatment-resistant depression: a retrospective observational analysis Journal of Comparative Effectiveness Research eoc costs episode of care costs healthcare utilization major depressive disorder mdd repetitive transcranial magnetic stimulation rtms saint saint neuromodulation system trd treatment-resistant depression |
| title | Resource utilization and economic outcomes following repetitive transcranial magnetic stimulation for treatment-resistant depression: a retrospective observational analysis |
| title_full | Resource utilization and economic outcomes following repetitive transcranial magnetic stimulation for treatment-resistant depression: a retrospective observational analysis |
| title_fullStr | Resource utilization and economic outcomes following repetitive transcranial magnetic stimulation for treatment-resistant depression: a retrospective observational analysis |
| title_full_unstemmed | Resource utilization and economic outcomes following repetitive transcranial magnetic stimulation for treatment-resistant depression: a retrospective observational analysis |
| title_short | Resource utilization and economic outcomes following repetitive transcranial magnetic stimulation for treatment-resistant depression: a retrospective observational analysis |
| title_sort | resource utilization and economic outcomes following repetitive transcranial magnetic stimulation for treatment resistant depression a retrospective observational analysis |
| topic | eoc costs episode of care costs healthcare utilization major depressive disorder mdd repetitive transcranial magnetic stimulation rtms saint saint neuromodulation system trd treatment-resistant depression |
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