Vagus nerve stimulation: a promising strategy to combat pyroptosis and inflammation in traumatic brain injury through the OX-A/NLRP3/caspase-1/GSDMD signaling pathway

Abstract Objectives Traumatic brain injury (TBI) affects millions annually and is a leading contributor to disability and mortality. The condition is marked by oxidative stress, inflammation, and pyroptosis, which play significant roles in neuronal impairment and functional deficits. Recent findings...

Full description

Saved in:
Bibliographic Details
Main Authors: Junwei Kang, Binkai Ren, Jia Wang, Yunliang Tang, Xiaoyang Dong
Format: Article
Language:English
Published: BMC 2025-07-01
Series:European Journal of Medical Research
Subjects:
Online Access:https://doi.org/10.1186/s40001-025-02870-3
Tags: Add Tag
No Tags, Be the first to tag this record!