Identification and validation of ANXA3 and SOCS3 as biomarkers for acute myocardial infarction related to sphingolipid metabolism

Identification and validation of ANXA3 and SOCS3 as biomarkers for acute myocardial infarction related to sphingolipid metabolism

Abstract Background Sphingolipid metabolism (SM) is linked to acute myocardial infarction (AMI), but its role remains unclear. This study explored SM-related genes (SMRGs) in AMI to support clinical diagnosis. Methods We analyzed datasets GSE48060 and GSE123342 to identify differentially expressed g...

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Bibliographic Details
Main Authors: Ling Sun, Lingyan He, Hai-Hua Pan, Chang-Lin Zhai
Format: Article
Language:English
Published: BMC 2025-08-01
Series:Hereditas
Subjects:
Acute myocardial infarction
Sphingolipid metabolism
Machine learning
Immune microenvironment
Single cell RNA analysis
Online Access:https://doi.org/10.1186/s41065-025-00515-3
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