Metabolic and behavioral features of acute hyperpurinergia and the maternal immune activation mouse model of autism spectrum disorder.

Metabolic and behavioral features of acute hyperpurinergia and the maternal immune activation mouse model of autism spectrum disorder.

Since 2012, studies in mice, rats, and humans have suggested that abnormalities in purinergic signaling may be a final common pathway for many genetic and environmental causes of autism spectrum disorder (ASD). The current study in mice was conducted to characterize the bioenergetic, metabolomic, br...

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Main Authors: Zarazuela Zolkipli-Cunningham, Jane C Naviaux, Tomohiro Nakayama, Charlotte M Hirsch, Jonathan M Monk, Kefeng Li, Lin Wang, Thuy P Le, Simone Meinardi, Donald R Blake, Robert K Naviaux
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0248771&type=printable
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