Seroprevalence of hepatitis A virus, hepatitis B virus, hepatitis C virus, and syphilis among human immunodeficiency virus-infected people at a university hospital, Turkey
Introduction Infections such as viral hepatitis and syphilis that share similar transmission routes with human immunodeficiency virus (HIV) may adversely affect the course of the disease. We aimed to determine the seroprevalence of viral hepatitis and syphilis among HIV-infected people at the initia...
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Termedia Publishing House
2020-08-01
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| Series: | Archives of Medical Science |
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| Online Access: | https://www.archivesofmedicalscience.com/Seroprevalence-of-hepatitis-A-virus-hepatitis-B-virus-hepatitis-C-virus-and-syphilis,118939,0,2.html |
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| author | Heval Can Bilek Aydın Deveci Esra Aksakal Tanyel |
| author_facet | Heval Can Bilek Aydın Deveci Esra Aksakal Tanyel |
| author_sort | Heval Can Bilek |
| collection | DOAJ |
| description | Introduction
Infections such as viral hepatitis and syphilis that share similar transmission routes with human immunodeficiency virus (HIV) may adversely affect the course of the disease. We aimed to determine the seroprevalence of viral hepatitis and syphilis among HIV-infected people at the initial stage of diagnosis.
Material and methods
The medical records of 336 HIV-infected people aged 18 years and older, who were followed up between 2005 and 2018 at a university hospital in Samsun, Turkey, were evaluated retrospectively in terms of initial serological markers for viral hepatitis and syphilis.
Results
Hepatitis B surface antigen (HBsAg) was positive in 13 (4.2%) of 303 patients, antibody to HBs antigen (anti-HBs) in 117 (39.2%) of 298 patients, antibody to hepatitis C virus (anti-HCV) in 3 (0.9%) of 301 patients, total antibody to hepatitis B core antigen (anti-HBc total) in 70 (29.2%) of 239 patients and total antibody to hepatitis A virus (anti-HAV total) in 224 (84.5%) of 265 patients. Hepatitis B virus (HBV) deoxyribonucleic acid (DNA) was detected in one (12.5%) of 8 patients with isolated anti-HBc. Of 224 patients who were examined for syphilis, 34 (15.1%) were positive for Treponema pallidum hemagglutination (TPHA).
Conclusions
In our study, high seroprevalence of syphilis and low immunity to HBV were detected. Health care facilities that follow up HIV-infected people should determine the serological profiles initially once the patients are diagnosed. It should be kept in mind that due to behavioral risk factors among HIV-infected people prevalence of coinfections may be higher than the rate in the community. |
| format | Article |
| id | doaj-art-dcd1a015c65e403e88459d89a00edbd4 |
| institution | DOAJ |
| issn | 1734-1922 1896-9151 |
| language | English |
| publishDate | 2020-08-01 |
| publisher | Termedia Publishing House |
| record_format | Article |
| series | Archives of Medical Science |
| spelling | doaj-art-dcd1a015c65e403e88459d89a00edbd42025-08-20T02:58:32ZengTermedia Publishing HouseArchives of Medical Science1734-19221896-91512020-08-0121243744110.5114/aoms.2020.97889118939Seroprevalence of hepatitis A virus, hepatitis B virus, hepatitis C virus, and syphilis among human immunodeficiency virus-infected people at a university hospital, TurkeyHeval Can Bilek0Aydın Deveci1Esra Aksakal Tanyel2Ondokuz Mayis University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Samsun, TurkeyOndokuz Mayis University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Samsun, TurkeyOndokuz Mayis University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Samsun, TurkeyIntroduction Infections such as viral hepatitis and syphilis that share similar transmission routes with human immunodeficiency virus (HIV) may adversely affect the course of the disease. We aimed to determine the seroprevalence of viral hepatitis and syphilis among HIV-infected people at the initial stage of diagnosis. Material and methods The medical records of 336 HIV-infected people aged 18 years and older, who were followed up between 2005 and 2018 at a university hospital in Samsun, Turkey, were evaluated retrospectively in terms of initial serological markers for viral hepatitis and syphilis. Results Hepatitis B surface antigen (HBsAg) was positive in 13 (4.2%) of 303 patients, antibody to HBs antigen (anti-HBs) in 117 (39.2%) of 298 patients, antibody to hepatitis C virus (anti-HCV) in 3 (0.9%) of 301 patients, total antibody to hepatitis B core antigen (anti-HBc total) in 70 (29.2%) of 239 patients and total antibody to hepatitis A virus (anti-HAV total) in 224 (84.5%) of 265 patients. Hepatitis B virus (HBV) deoxyribonucleic acid (DNA) was detected in one (12.5%) of 8 patients with isolated anti-HBc. Of 224 patients who were examined for syphilis, 34 (15.1%) were positive for Treponema pallidum hemagglutination (TPHA). Conclusions In our study, high seroprevalence of syphilis and low immunity to HBV were detected. Health care facilities that follow up HIV-infected people should determine the serological profiles initially once the patients are diagnosed. It should be kept in mind that due to behavioral risk factors among HIV-infected people prevalence of coinfections may be higher than the rate in the community.https://www.archivesofmedicalscience.com/Seroprevalence-of-hepatitis-A-virus-hepatitis-B-virus-hepatitis-C-virus-and-syphilis,118939,0,2.htmlhepatitis b virushepatitis c virushuman immunodeficiency virussyphiliscoinfectionprevalence |
| spellingShingle | Heval Can Bilek Aydın Deveci Esra Aksakal Tanyel Seroprevalence of hepatitis A virus, hepatitis B virus, hepatitis C virus, and syphilis among human immunodeficiency virus-infected people at a university hospital, Turkey Archives of Medical Science hepatitis b virus hepatitis c virus human immunodeficiency virus syphilis coinfection prevalence |
| title | Seroprevalence of hepatitis A virus, hepatitis B virus, hepatitis C virus, and syphilis among human immunodeficiency virus-infected people at a university hospital, Turkey |
| title_full | Seroprevalence of hepatitis A virus, hepatitis B virus, hepatitis C virus, and syphilis among human immunodeficiency virus-infected people at a university hospital, Turkey |
| title_fullStr | Seroprevalence of hepatitis A virus, hepatitis B virus, hepatitis C virus, and syphilis among human immunodeficiency virus-infected people at a university hospital, Turkey |
| title_full_unstemmed | Seroprevalence of hepatitis A virus, hepatitis B virus, hepatitis C virus, and syphilis among human immunodeficiency virus-infected people at a university hospital, Turkey |
| title_short | Seroprevalence of hepatitis A virus, hepatitis B virus, hepatitis C virus, and syphilis among human immunodeficiency virus-infected people at a university hospital, Turkey |
| title_sort | seroprevalence of hepatitis a virus hepatitis b virus hepatitis c virus and syphilis among human immunodeficiency virus infected people at a university hospital turkey |
| topic | hepatitis b virus hepatitis c virus human immunodeficiency virus syphilis coinfection prevalence |
| url | https://www.archivesofmedicalscience.com/Seroprevalence-of-hepatitis-A-virus-hepatitis-B-virus-hepatitis-C-virus-and-syphilis,118939,0,2.html |
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