Host inflammatory dynamics reveal placental immune modulation by Group B Streptococcus during pregnancy

Host inflammatory dynamics reveal placental immune modulation by Group B Streptococcus during pregnancy

Abstract Group B Streptococcus (GBS) is a pathobiont that can ascend to the placenta and cause adverse pregnancy outcomes, in part through production of the toxin β‐hemolysin/cytolysin (β‐h/c). Innate immune cells have been implicated in the response to GBS infection, but the impact of β‐h/c on thei...

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Bibliographic Details
Main Authors: Felicia Kuperwaser, Gal Avital, Michelle J Vaz, Kristen N Noble, Allison N Dammann, Tara M Randis, David M Aronoff, Adam J Ratner, Itai Yanai
Format: Article
Language:English
Published: Springer Nature 2023-02-01
Series:Molecular Systems Biology
Subjects:
bacterial infection
group B Streptococcus (GBS)
host–pathogen interactions
innate immunity
placenta
Online Access:https://doi.org/10.15252/msb.202211021
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https://doi.org/10.15252/msb.202211021

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