Localizing dorsolateral prefrontal cortex for noninvasive brain stimulation in adolescents: A comparison between BeamF3 and 10–20 EEG systems: A cross-sectional study

Background: The dorsolateral prefrontal cortex (DLPFC) is implicated in neuropsychiatric disorders. It is a primary target region for noninvasive brain stimulation (NIBS). BeamF3 is a simplified method of localization of DLPFC for neuromodulation. However, the accuracy of this method has not been ex...

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Main Authors: Sakhardande Kasturi Atmaram, Harsh Pathak, Harshini Manohar, Vanteemar S. Sreeraj, Ganesan Venkatasubramanian, John Vijay Sagar Kommu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-03-01
Series:Indian Journal of Psychiatry
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Online Access:https://journals.lww.com/10.4103/indianjpsychiatry.indianjpsychiatry_972_24
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Summary:Background: The dorsolateral prefrontal cortex (DLPFC) is implicated in neuropsychiatric disorders. It is a primary target region for noninvasive brain stimulation (NIBS). BeamF3 is a simplified method of localization of DLPFC for neuromodulation. However, the accuracy of this method has not been examined in children. Aim: To compare the localization of DLPFC via BeamF3 and 10–20 electroencephalogram (EEG) systems in adolescents with neuropsychiatric disorders. Methods: Twenty adolescents (10–15 years) were recruited from the in-patient child and adolescent psychiatry unit of our center. DLPFC localization was done and compared between the BeamF3 and 10–20 EEG systems. DLPFC localization based on the BeamF3 method at anterior/anterolateral/lateral position was compared with 10–20 EEG systems in 70% of adolescents. Results: The mean difference in DLPFC localization was 1.10 ± 0.81 cm (0–3 cm), with a difference of ≥1 cm in 70% of adolescents. This study found a difference between Beam F3 and 10–20 EEG systems in terms of localization of DLPFC in adolescents. Conclusion: Comparison of these methods with MRI-guided methods may be necessary, especially when highly focal stimulation is desired for treatment in adolescents.
ISSN:0019-5545
1998-3794