Dysregulation of bile acid metabolism in patients with colorectal cancer

Dysregulation of bile acid metabolism in patients with colorectal cancer

Abstract Bile acid (BA) metabolism and signaling may influence cancer risk. We investigated differences in circulating BA composition between healthy controls and patients with colorectal cancer (CRC) and assessed the epithelial–mesenchymal transition (EMT) in CRC cell lines exposed to chenodeoxycho...

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Main Authors: Su-Mi Lee, Seon-Young Park, Khom Sophallika, Jin Ook Chung, Yong Wook Jung, Dong Hyun Kim, Jin Won Kim, Hyun Soo Kim, Jae Hyun Yoon, Young Do Jung, Jae Kyun Ju, Jun Seong Chung, Han Deok Kwak
Format: Article
Language:English
Published: Nature Portfolio 2025-08-01
Series:Scientific Reports
Subjects:
Bile acids
Colorectal cancer
Epithelial–mesenchymal transition
Chenodeoxycholic acid
Online Access:https://doi.org/10.1038/s41598-025-15159-6
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https://doi.org/10.1038/s41598-025-15159-6

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