Synergistic improvement of the mechanical and biological performance of Si3N4 by incorporating nanostructured graphene
Achieving synergy between mechanical and biological performance has long been a challenge in developing silicon nitride (Si3N4) as a bone regeneration implant material. In this study, a nanostructured graphene-toughened Si3N4 composite (Si3N4–G) was prepared, and the mechanical and biological proper...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2025-02-01
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| Series: | Journal of Advanced Ceramics |
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| Online Access: | https://www.sciopen.com/article/10.26599/JAC.2024.9221026 |
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| author | Zhe Zhan Bin Deng Yanru Chen Xinghong Zhang Jinzhu Song |
| author_facet | Zhe Zhan Bin Deng Yanru Chen Xinghong Zhang Jinzhu Song |
| author_sort | Zhe Zhan |
| collection | DOAJ |
| description | Achieving synergy between mechanical and biological performance has long been a challenge in developing silicon nitride (Si3N4) as a bone regeneration implant material. In this study, a nanostructured graphene-toughened Si3N4 composite (Si3N4–G) was prepared, and the mechanical and biological properties of the resulting Si3N4–G composite were compared with those of Si3N4 ceramics without graphene addition. The incorporation of nanostructured graphene substantially improves the mechanical properties of Si3N4. Furthermore, the nanoscale thickness of graphene enhances antibacterial activity through a “cutting” effect, while its high specific surface area promotes cell adhesion, activating mechanosensitive pathways linked to osteogenic differentiation. This work provides new insights into the potential applications of Si3N4-based bio-ceramics in bone tissue engineering. |
| format | Article |
| id | doaj-art-dcc3e19545024de98da7a67660d5f2f6 |
| institution | DOAJ |
| issn | 2226-4108 2227-8508 |
| language | English |
| publishDate | 2025-02-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Journal of Advanced Ceramics |
| spelling | doaj-art-dcc3e19545024de98da7a67660d5f2f62025-08-20T02:56:44ZengTsinghua University PressJournal of Advanced Ceramics2226-41082227-85082025-02-01142922102610.26599/JAC.2024.9221026Synergistic improvement of the mechanical and biological performance of Si3N4 by incorporating nanostructured grapheneZhe Zhan0Bin Deng1Yanru Chen2Xinghong Zhang3Jinzhu Song4School of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, ChinaDepartment of Stomatology, the First Medical Center, Chinese PLA General Hospital, Beijing 100853, ChinaDepartment of Stomatology, the First Medical Center, Chinese PLA General Hospital, Beijing 100853, ChinaCenter for Composite Materials and Structures, Harbin Institute of Technology, Harbin 150001, ChinaSchool of Life Science and Technology, Harbin Institute of Technology, Harbin 150001, ChinaAchieving synergy between mechanical and biological performance has long been a challenge in developing silicon nitride (Si3N4) as a bone regeneration implant material. In this study, a nanostructured graphene-toughened Si3N4 composite (Si3N4–G) was prepared, and the mechanical and biological properties of the resulting Si3N4–G composite were compared with those of Si3N4 ceramics without graphene addition. The incorporation of nanostructured graphene substantially improves the mechanical properties of Si3N4. Furthermore, the nanoscale thickness of graphene enhances antibacterial activity through a “cutting” effect, while its high specific surface area promotes cell adhesion, activating mechanosensitive pathways linked to osteogenic differentiation. This work provides new insights into the potential applications of Si3N4-based bio-ceramics in bone tissue engineering.https://www.sciopen.com/article/10.26599/JAC.2024.9221026silicon nitride (si3n4)graphene (g)mechanical propertiesbiocompatibility |
| spellingShingle | Zhe Zhan Bin Deng Yanru Chen Xinghong Zhang Jinzhu Song Synergistic improvement of the mechanical and biological performance of Si3N4 by incorporating nanostructured graphene Journal of Advanced Ceramics silicon nitride (si3n4) graphene (g) mechanical properties biocompatibility |
| title | Synergistic improvement of the mechanical and biological performance of Si3N4 by incorporating nanostructured graphene |
| title_full | Synergistic improvement of the mechanical and biological performance of Si3N4 by incorporating nanostructured graphene |
| title_fullStr | Synergistic improvement of the mechanical and biological performance of Si3N4 by incorporating nanostructured graphene |
| title_full_unstemmed | Synergistic improvement of the mechanical and biological performance of Si3N4 by incorporating nanostructured graphene |
| title_short | Synergistic improvement of the mechanical and biological performance of Si3N4 by incorporating nanostructured graphene |
| title_sort | synergistic improvement of the mechanical and biological performance of si3n4 by incorporating nanostructured graphene |
| topic | silicon nitride (si3n4) graphene (g) mechanical properties biocompatibility |
| url | https://www.sciopen.com/article/10.26599/JAC.2024.9221026 |
| work_keys_str_mv | AT zhezhan synergisticimprovementofthemechanicalandbiologicalperformanceofsi3n4byincorporatingnanostructuredgraphene AT bindeng synergisticimprovementofthemechanicalandbiologicalperformanceofsi3n4byincorporatingnanostructuredgraphene AT yanruchen synergisticimprovementofthemechanicalandbiologicalperformanceofsi3n4byincorporatingnanostructuredgraphene AT xinghongzhang synergisticimprovementofthemechanicalandbiologicalperformanceofsi3n4byincorporatingnanostructuredgraphene AT jinzhusong synergisticimprovementofthemechanicalandbiologicalperformanceofsi3n4byincorporatingnanostructuredgraphene |