Visual outcomes with a non-diffractive enhanced depth-of-focus IOL in patients with age-related macular degeneration
PurposeTo evaluate visual function in eyes with age-related macular degeneration (AMD) implanted with a non-diffractive enhanced depth-of-focus (EDOF) intraocular lens (IOL) after cataract surgery.DesignProspective, observational, non-randomized clinical study.MethodsTwenty-two eyes from 22 patients...
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Frontiers Media S.A.
2025-06-01
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fmed.2025.1505401/full |
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| author | Juan Carlos Elvira Patricia Devesa Belén Elvira-Giner Pedro Tañá-Sanz Paz Orts-Vila Pedro Tañá-Rivero |
| author_facet | Juan Carlos Elvira Patricia Devesa Belén Elvira-Giner Pedro Tañá-Sanz Paz Orts-Vila Pedro Tañá-Rivero |
| author_sort | Juan Carlos Elvira |
| collection | DOAJ |
| description | PurposeTo evaluate visual function in eyes with age-related macular degeneration (AMD) implanted with a non-diffractive enhanced depth-of-focus (EDOF) intraocular lens (IOL) after cataract surgery.DesignProspective, observational, non-randomized clinical study.MethodsTwenty-two eyes from 22 patients diagnosed with AMD and cataracts were submitted to standard cataract surgery with a non-diffractive EDOF IOL implantation (AcrySof IQ Vivity). We measured monocular uncorrected and best-corrected-distance visual acuity (UDVA and CDVA), uncorrected- and distance-corrected-intermediate visual acuity (UIVA and DCIVA), uncorrected- and distance-corrected-near visual acuity (UNVA and DCNVA), manifest refractive spherical equivalent (MRSE) and cylinder, monocular defocus curve and patient-reported outcome questionnaires (Catquest-9SF and NEI VFQ-25). Follow-up visits were carried out at 1, 3 and 6 months post-surgery.ResultsAt 6 months post-surgery all eyes were within ± 0.50 D with a mean MRSE of −0.19 ± 0.20 D, 95.45% had a refractive cylinder of ≤ 0.50 D with a mean cylinder of −0.24 ± 0.27 D. The mean values of postoperative monocular CDVA, DCIVA, and DCNVA were 0.02 ± 0.08, 0.16 ± 0.11, and 0.26 ± 0.15 logMAR, respectively. The defocus curve showed good visual acuity at distance and intermediate with a depth-of-focus of about 1.60 D. A total of 81.82% of patients did not report any difficulty with their vision in their everyday-life and 86.36% reported being quite satisfied to very satisfied with their current vision. The NEI VFQ-25 showed that all values improved significantly (p < 0.05) after the surgery in the different parameters analyzed except for ocular pain (p = 0.390) and color vision (p = 0.333).ConclusionThe use of a non-diffractive EDOF IOL in AMD eyes with cataracts is a safe and effective surgical approach for visually correcting aphakia, providing good visual acuity at far and intermediate distances. Our outcomes support the use of non-diffractive EDOF IOLs in patients with AMD diagnosed with cataracts aiming to obtain spectacle-independence at far and intermediate distances. |
| format | Article |
| id | doaj-art-dcc3302af4074f9e97eeca7340559cdb |
| institution | DOAJ |
| issn | 2296-858X |
| language | English |
| publishDate | 2025-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Medicine |
| spelling | doaj-art-dcc3302af4074f9e97eeca7340559cdb2025-08-20T03:20:55ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-06-011210.3389/fmed.2025.15054011505401Visual outcomes with a non-diffractive enhanced depth-of-focus IOL in patients with age-related macular degenerationJuan Carlos ElviraPatricia DevesaBelén Elvira-GinerPedro Tañá-SanzPaz Orts-VilaPedro Tañá-RiveroPurposeTo evaluate visual function in eyes with age-related macular degeneration (AMD) implanted with a non-diffractive enhanced depth-of-focus (EDOF) intraocular lens (IOL) after cataract surgery.DesignProspective, observational, non-randomized clinical study.MethodsTwenty-two eyes from 22 patients diagnosed with AMD and cataracts were submitted to standard cataract surgery with a non-diffractive EDOF IOL implantation (AcrySof IQ Vivity). We measured monocular uncorrected and best-corrected-distance visual acuity (UDVA and CDVA), uncorrected- and distance-corrected-intermediate visual acuity (UIVA and DCIVA), uncorrected- and distance-corrected-near visual acuity (UNVA and DCNVA), manifest refractive spherical equivalent (MRSE) and cylinder, monocular defocus curve and patient-reported outcome questionnaires (Catquest-9SF and NEI VFQ-25). Follow-up visits were carried out at 1, 3 and 6 months post-surgery.ResultsAt 6 months post-surgery all eyes were within ± 0.50 D with a mean MRSE of −0.19 ± 0.20 D, 95.45% had a refractive cylinder of ≤ 0.50 D with a mean cylinder of −0.24 ± 0.27 D. The mean values of postoperative monocular CDVA, DCIVA, and DCNVA were 0.02 ± 0.08, 0.16 ± 0.11, and 0.26 ± 0.15 logMAR, respectively. The defocus curve showed good visual acuity at distance and intermediate with a depth-of-focus of about 1.60 D. A total of 81.82% of patients did not report any difficulty with their vision in their everyday-life and 86.36% reported being quite satisfied to very satisfied with their current vision. The NEI VFQ-25 showed that all values improved significantly (p < 0.05) after the surgery in the different parameters analyzed except for ocular pain (p = 0.390) and color vision (p = 0.333).ConclusionThe use of a non-diffractive EDOF IOL in AMD eyes with cataracts is a safe and effective surgical approach for visually correcting aphakia, providing good visual acuity at far and intermediate distances. Our outcomes support the use of non-diffractive EDOF IOLs in patients with AMD diagnosed with cataracts aiming to obtain spectacle-independence at far and intermediate distances.https://www.frontiersin.org/articles/10.3389/fmed.2025.1505401/fullage-related macular degenerationenhanced depth-of-focuscataractsintraocular lenspatient satisfaction |
| spellingShingle | Juan Carlos Elvira Patricia Devesa Belén Elvira-Giner Pedro Tañá-Sanz Paz Orts-Vila Pedro Tañá-Rivero Visual outcomes with a non-diffractive enhanced depth-of-focus IOL in patients with age-related macular degeneration Frontiers in Medicine age-related macular degeneration enhanced depth-of-focus cataracts intraocular lens patient satisfaction |
| title | Visual outcomes with a non-diffractive enhanced depth-of-focus IOL in patients with age-related macular degeneration |
| title_full | Visual outcomes with a non-diffractive enhanced depth-of-focus IOL in patients with age-related macular degeneration |
| title_fullStr | Visual outcomes with a non-diffractive enhanced depth-of-focus IOL in patients with age-related macular degeneration |
| title_full_unstemmed | Visual outcomes with a non-diffractive enhanced depth-of-focus IOL in patients with age-related macular degeneration |
| title_short | Visual outcomes with a non-diffractive enhanced depth-of-focus IOL in patients with age-related macular degeneration |
| title_sort | visual outcomes with a non diffractive enhanced depth of focus iol in patients with age related macular degeneration |
| topic | age-related macular degeneration enhanced depth-of-focus cataracts intraocular lens patient satisfaction |
| url | https://www.frontiersin.org/articles/10.3389/fmed.2025.1505401/full |
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