The Role of Adherence and Retreatment in De Novo Emergence of MDR-TB.

The Role of Adherence and Retreatment in De Novo Emergence of MDR-TB.

Treatment failure after therapy of pulmonary tuberculosis (TB) infections is an important challenge, especially when it coincides with de novo emergence of multi-drug-resistant TB (MDR-TB). We seek to explore possible causes why MDR-TB has been found to occur much more often in patients with a histo...

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Bibliographic Details
Main Authors: Dominique Cadosch, Pia Abel Zur Wiesch, Roger Kouyos, Sebastian Bonhoeffer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-03-01
Series:PLoS Computational Biology
Online Access:https://journals.plos.org/ploscompbiol/article/file?id=10.1371/journal.pcbi.1004749&type=printable
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