Influence of bile acid derivates on morphine analgesic effect in mice

Influence of bile acid derivates on morphine analgesic effect in mice

Background/Aim. It is known that bile acids improve the absorption, bioavailability and pharmacodynamic characteristics of some drugs. Morphine analgesia is produced by activation of opioid receptors within the central nervous system (CNS) at both spinal and supraspinal levels. Since a morp...

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Bibliographic Details
Main Authors: Vasović Velibor, Vukmirović Saša, Mikov Momir, Mikov Ivan, Budakov Zorana, Stilinović Nebojša, Milijašević Boris
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2014-01-01
Series:Vojnosanitetski Pregled
Subjects:
morphine
mice
bile acids and salts
blood-brain barrier
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2014/0042-84501400007V.pdf
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