Adipose-derived stem cell exosomes attenuates myofibroblast transformation via inhibiting autophagy through TGF-β/Smad2 axis in oral submucosal fibrosis

Abstract Oral submucous fibrosis (OSF) is a precancerous condition that poses substantial health risks. OSF is mainly caused by betel nut chewing behavior, but its pathogenesis is still unclear and there is no effective treatment strategy. The transformation of fibroblasts to myofibroblast is the ke...

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Bibliographic Details
Main Authors: Jinhao Xu, Yujing Wang, Zifei Shao, Yuxi Zhou, Xin Bin, Lian Liu, Weiman Huang, Xidi Wang, Yanjia Hu, Kun Li
Format: Article
Language:English
Published: BMC 2024-12-01
Series:Journal of Nanobiotechnology
Subjects:
Online Access:https://doi.org/10.1186/s12951-024-03067-2
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