Formulation and pharmaceutical development of quetiapine fumarate sustained release matrix tablets using a QbD approach
The main objective of the present study was to apply QbD methodology in the development of once-a-day sustained release quetiapine tablets. The quality target product profile (QTPP) was defined after the pharmaceutical properties and kinetic release of the innovator product, Seroquel XR 200 mg. For...
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Main Authors: | Gavan Alexandru, Porfire Alina, Marina Cristina, Tomuta Ioan |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2017-03-01
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Series: | Acta Pharmaceutica |
Subjects: | |
Online Access: | https://doi.org/10.1515/acph-2017-0009 |
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