A Multicenter Randomized Controlled Study on Pharmacokinetic‐Guided Vancomycin Use in Children With Severe Infections

A Multicenter Randomized Controlled Study on Pharmacokinetic‐Guided Vancomycin Use in Children With Severe Infections

ABSTRACT This study is a multicenter, randomized controlled prospective trial aimed at evaluating the effects of two vancomycin pharmacokinetics/pharmacodynamics (PK/PD) parameters on clinical outcomes in children with different severe infections: trough concentration (Cmin) and the area under the c...

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Main Authors: Fuxiang He, Ya Yang, Bo Zhou, Chengcheng Li, Yu Feng, Xuexin Wang, Haifeng Liu, Yuhang Hu, Hongmin Fu, Yingbo Zou, Guoying Zhang, Jianli Chen, Yueqiang Fu, Shufang Xiao, Lan Hu, Chengjun Liu
Format: Article
Language:English
Published: Wiley 2025-08-01
Series:Clinical and Translational Science
Subjects:
age groups
clinical efficacy
infections
pediatrics
pharmacokinetics
vancomycin
Online Access:https://doi.org/10.1111/cts.70309
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