Modern concept of diastolic heart failure
The paper discusses modern aspects of epidemiology, pathogenesis, clinical course, diagnostics, and treatment of the patients with chronic heart failure (CHF) and intact left ventricular ejection fraction (LVEF). CHF with intact LVEF comprises over 50% of all CHF cases, and is more prevalent in elde...
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| Format: | Article |
| Language: | Russian |
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«SILICEA-POLIGRAF» LLC
1970-01-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/2169 |
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| _version_ | 1849250416698589184 |
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| author | F. T. Ageev |
| author_facet | F. T. Ageev |
| author_sort | F. T. Ageev |
| collection | DOAJ |
| description | The paper discusses modern aspects of epidemiology, pathogenesis, clinical course, diagnostics, and treatment of the patients with chronic heart failure (CHF) and intact left ventricular ejection fraction (LVEF). CHF with intact LVEF comprises over 50% of all CHF cases, and is more prevalent in elderly women. Its leading causes include arterial hypertension (AH) and diabetes mellitus (DM). Current diagnostic problems are related to over-estimated role of LVEF reduction, which reflects substantial myocardial damage not typical for AH and DM. The limitations of classical Doppler ultrasound in diastolic dysfunction (DD) diagnostics are discussed. The combination of classical and tissue Doppler ultrasound provides a more precise estimation of systolic and diastolic LV function. This method, in combination with natriuretic peptide level measurement, is the basis for the diagnostic algorithm of CHF with intact LVEF. A new hemodynamic concept of CHF development is presented. The key clinical trials on the treatment of CHF with intact LVEF are reviewed. In conclusion, the author discusses strengths and limitations of the two concepts of CHF with intact LVEF, as a separate disease or a phenotypical manifestation (stage) of “classical” systolic CHF. |
| format | Article |
| id | doaj-art-dca818da2a5a490999e105feb898c7fd |
| institution | Kabale University |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 1970-01-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-dca818da2a5a490999e105feb898c7fd2025-08-20T03:57:17Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01251970-01-0197971041878Modern concept of diastolic heart failureF. T. Ageev0A.L. Myasnikov Research Institute of Clinical Cardiology, Russian Cardiology Scientific and Clinical Complex. MoscowThe paper discusses modern aspects of epidemiology, pathogenesis, clinical course, diagnostics, and treatment of the patients with chronic heart failure (CHF) and intact left ventricular ejection fraction (LVEF). CHF with intact LVEF comprises over 50% of all CHF cases, and is more prevalent in elderly women. Its leading causes include arterial hypertension (AH) and diabetes mellitus (DM). Current diagnostic problems are related to over-estimated role of LVEF reduction, which reflects substantial myocardial damage not typical for AH and DM. The limitations of classical Doppler ultrasound in diastolic dysfunction (DD) diagnostics are discussed. The combination of classical and tissue Doppler ultrasound provides a more precise estimation of systolic and diastolic LV function. This method, in combination with natriuretic peptide level measurement, is the basis for the diagnostic algorithm of CHF with intact LVEF. A new hemodynamic concept of CHF development is presented. The key clinical trials on the treatment of CHF with intact LVEF are reviewed. In conclusion, the author discusses strengths and limitations of the two concepts of CHF with intact LVEF, as a separate disease or a phenotypical manifestation (stage) of “classical” systolic CHF.https://cardiovascular.elpub.ru/jour/article/view/2169diastolic heart failureheart failure with intact systolic function |
| spellingShingle | F. T. Ageev Modern concept of diastolic heart failure Кардиоваскулярная терапия и профилактика diastolic heart failure heart failure with intact systolic function |
| title | Modern concept of diastolic heart failure |
| title_full | Modern concept of diastolic heart failure |
| title_fullStr | Modern concept of diastolic heart failure |
| title_full_unstemmed | Modern concept of diastolic heart failure |
| title_short | Modern concept of diastolic heart failure |
| title_sort | modern concept of diastolic heart failure |
| topic | diastolic heart failure heart failure with intact systolic function |
| url | https://cardiovascular.elpub.ru/jour/article/view/2169 |
| work_keys_str_mv | AT ftageev modernconceptofdiastolicheartfailure |