Research progress in the establishment of mouse models of chronic rhinosinusitis
Chronic nasal inflammation， such as rhinitis and sinusitis， is a common chronic disease that affects people’s quality of life for a long period of time. Its pathogenesis and mechanism are still unclear. The establishment of animal models is an effective approach to explore the pathogenesis， among wh...
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| Format: | Article |
| Language: | zho |
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Editorial Office of Journal of New Medicine
2024-10-01
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| Series: | Xin yixue |
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| Online Access: | https://www.xinyixue.cn/fileup/0253-9802/PDF/1731477234538-541526284.pdf |
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| author | CHEN Yuan, SHEN Yang, WANG Ji, LU Tao, ZHENG Bowen, YANG Yucheng |
| author_facet | CHEN Yuan, SHEN Yang, WANG Ji, LU Tao, ZHENG Bowen, YANG Yucheng |
| author_sort | CHEN Yuan, SHEN Yang, WANG Ji, LU Tao, ZHENG Bowen, YANG Yucheng |
| collection | DOAJ |
| description | Chronic nasal inflammation， such as rhinitis and sinusitis， is a common chronic disease that affects people’s quality of life for a long period of time. Its pathogenesis and mechanism are still unclear. The establishment of animal models is an effective approach to explore the pathogenesis， among which the establishment of mouse models of chronic nasal inflammation has been rapidly developed in recent years. The aim of this review is to summarize the research status of chronic rhinosinusitis and allergic rhinitis modeling in mice at home and abroad， especially the progress in eosinophilic chronic rhinosinusitis mouse models， which plays an important role in the development of new drugs to prevent and control chronic nasal inflammation or further elucidation of its pathogenesis. |
| format | Article |
| id | doaj-art-dca73ec6984d4d73a942ae13de362acc |
| institution | Kabale University |
| issn | 0253-9802 |
| language | zho |
| publishDate | 2024-10-01 |
| publisher | Editorial Office of Journal of New Medicine |
| record_format | Article |
| series | Xin yixue |
| spelling | doaj-art-dca73ec6984d4d73a942ae13de362acc2024-11-13T07:15:04ZzhoEditorial Office of Journal of New MedicineXin yixue0253-98022024-10-01551081882710.3969/j.issn.0253-9802.2024.10.009Research progress in the establishment of mouse models of chronic rhinosinusitisCHEN Yuan, SHEN Yang, WANG Ji, LU Tao, ZHENG Bowen, YANG Yucheng0Department of Otolaryngology， the First Affiliated Hospital of Chongqing Medical University， Chongqing 400016， ChinaChronic nasal inflammation， such as rhinitis and sinusitis， is a common chronic disease that affects people’s quality of life for a long period of time. Its pathogenesis and mechanism are still unclear. The establishment of animal models is an effective approach to explore the pathogenesis， among which the establishment of mouse models of chronic nasal inflammation has been rapidly developed in recent years. The aim of this review is to summarize the research status of chronic rhinosinusitis and allergic rhinitis modeling in mice at home and abroad， especially the progress in eosinophilic chronic rhinosinusitis mouse models， which plays an important role in the development of new drugs to prevent and control chronic nasal inflammation or further elucidation of its pathogenesis.https://www.xinyixue.cn/fileup/0253-9802/PDF/1731477234538-541526284.pdfmouse model|eosinophil|nasal polyps|chronic rhinosinusitis|allergic rhinitis |
| spellingShingle | CHEN Yuan, SHEN Yang, WANG Ji, LU Tao, ZHENG Bowen, YANG Yucheng Research progress in the establishment of mouse models of chronic rhinosinusitis Xin yixue mouse model|eosinophil|nasal polyps|chronic rhinosinusitis|allergic rhinitis |
| title | Research progress in the establishment of mouse models of chronic rhinosinusitis |
| title_full | Research progress in the establishment of mouse models of chronic rhinosinusitis |
| title_fullStr | Research progress in the establishment of mouse models of chronic rhinosinusitis |
| title_full_unstemmed | Research progress in the establishment of mouse models of chronic rhinosinusitis |
| title_short | Research progress in the establishment of mouse models of chronic rhinosinusitis |
| title_sort | research progress in the establishment of mouse models of chronic rhinosinusitis |
| topic | mouse model|eosinophil|nasal polyps|chronic rhinosinusitis|allergic rhinitis |
| url | https://www.xinyixue.cn/fileup/0253-9802/PDF/1731477234538-541526284.pdf |
| work_keys_str_mv | AT chenyuanshenyangwangjilutaozhengbowenyangyucheng researchprogressintheestablishmentofmousemodelsofchronicrhinosinusitis |