Influence of Neutralization Precipitation Conditions on the Physical Stability of Amorphous Solid Pharmaceuticals

This research focused on the precipitation of amorphous forms of nilotinib with high physical stability through the manipulation of various parameters in the neutralization reaction, specifically the quantity of nilotinib, the pH value, and the concentration of HCl. To assess the physical stability...

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Bibliographic Details
Main Authors: Zhihui Yuan, Xu Liao, Bowen Zhang, Asad Nawaz, Zunhua Li
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/4/764
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