Comparison of the electrophysiological properties of the pulmonary veins between paroxysmal and persistent atrial fibrillation
Abstract Background The role of the pulmonary veins (PVs) as triggers in atrial fibrillation (AF) is well‐known; however, their detailed electrophysiological properties have not been thoroughly examined. Objective This study aimed to investigate the electrophysiological properties of the PVs between...
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Wiley
2024-02-01
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| Series: | Journal of Arrhythmia |
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| Online Access: | https://doi.org/10.1002/joa3.12981 |
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| author | Hitoshi Mori Akira Hamabe Daisuke Kawano Tsukasa Naganuma Mai Tahara Yodo Gatate Toyokazu Kimura Hirotsugu Tabata Ritsushi Kato |
| author_facet | Hitoshi Mori Akira Hamabe Daisuke Kawano Tsukasa Naganuma Mai Tahara Yodo Gatate Toyokazu Kimura Hirotsugu Tabata Ritsushi Kato |
| author_sort | Hitoshi Mori |
| collection | DOAJ |
| description | Abstract Background The role of the pulmonary veins (PVs) as triggers in atrial fibrillation (AF) is well‐known; however, their detailed electrophysiological properties have not been thoroughly examined. Objective This study aimed to investigate the electrophysiological properties of the PVs between paroxysmal AF (pAF) and persistent AF (perAF). Methods Prior to catheter ablation in patients with pAF (n = 51) and perAF (n = 41), a voltage map of the left atrium and PVs was created under sinus rhythm, and the area of the myocardial sleeves in the PVs and their electrophysiological characteristics, including the pacing threshold and effective refractory period (ERP), were compared between the two groups. Results Compared with perAF, the myocardial sleeves of PVs for pAF were significantly larger for all PVs. The ERP for perAF was significantly shorter than that for pAF for all PVs. The pacing threshold for perAF was significantly higher than that for pAF for the right and left superior PVs. Conclusion In patients with perAF, a decrease in the normal myocardial sleeves and a shortening of the ERP were observed for all PVs. Those changes in the electrophysiological properties of the PVs might be related to the persistence of AF. |
| format | Article |
| id | doaj-art-dc9e762822fa407f8a587a9b107d4d0c |
| institution | DOAJ |
| issn | 1880-4276 1883-2148 |
| language | English |
| publishDate | 2024-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Arrhythmia |
| spelling | doaj-art-dc9e762822fa407f8a587a9b107d4d0c2025-08-20T03:12:38ZengWileyJournal of Arrhythmia1880-42761883-21482024-02-01401838910.1002/joa3.12981Comparison of the electrophysiological properties of the pulmonary veins between paroxysmal and persistent atrial fibrillationHitoshi Mori0Akira Hamabe1Daisuke Kawano2Tsukasa Naganuma3Mai Tahara4Yodo Gatate5Toyokazu Kimura6Hirotsugu Tabata7Ritsushi Kato8Department of Cardiology Japan Self Defense Forces Central Hospital Tokyo JapanDepartment of Cardiology Japan Self Defense Forces Central Hospital Tokyo JapanDepartment of Cardiology Japan Self Defense Forces Central Hospital Tokyo JapanDepartment of Cardiology Japan Self Defense Forces Central Hospital Tokyo JapanDepartment of Cardiology Japan Self Defense Forces Central Hospital Tokyo JapanDepartment of Cardiology Japan Self Defense Forces Central Hospital Tokyo JapanDepartment of Cardiology Japan Self Defense Forces Central Hospital Tokyo JapanDepartment of Cardiology Japan Self Defense Forces Central Hospital Tokyo JapanDepartment of Cardiology Saitama Medical University, International Medical Center Hidaka JapanAbstract Background The role of the pulmonary veins (PVs) as triggers in atrial fibrillation (AF) is well‐known; however, their detailed electrophysiological properties have not been thoroughly examined. Objective This study aimed to investigate the electrophysiological properties of the PVs between paroxysmal AF (pAF) and persistent AF (perAF). Methods Prior to catheter ablation in patients with pAF (n = 51) and perAF (n = 41), a voltage map of the left atrium and PVs was created under sinus rhythm, and the area of the myocardial sleeves in the PVs and their electrophysiological characteristics, including the pacing threshold and effective refractory period (ERP), were compared between the two groups. Results Compared with perAF, the myocardial sleeves of PVs for pAF were significantly larger for all PVs. The ERP for perAF was significantly shorter than that for pAF for all PVs. The pacing threshold for perAF was significantly higher than that for pAF for the right and left superior PVs. Conclusion In patients with perAF, a decrease in the normal myocardial sleeves and a shortening of the ERP were observed for all PVs. Those changes in the electrophysiological properties of the PVs might be related to the persistence of AF.https://doi.org/10.1002/joa3.12981atrial fibrillationelectrophysiological studylow‐voltage areaspulmonary veinsubstrate |
| spellingShingle | Hitoshi Mori Akira Hamabe Daisuke Kawano Tsukasa Naganuma Mai Tahara Yodo Gatate Toyokazu Kimura Hirotsugu Tabata Ritsushi Kato Comparison of the electrophysiological properties of the pulmonary veins between paroxysmal and persistent atrial fibrillation Journal of Arrhythmia atrial fibrillation electrophysiological study low‐voltage areas pulmonary vein substrate |
| title | Comparison of the electrophysiological properties of the pulmonary veins between paroxysmal and persistent atrial fibrillation |
| title_full | Comparison of the electrophysiological properties of the pulmonary veins between paroxysmal and persistent atrial fibrillation |
| title_fullStr | Comparison of the electrophysiological properties of the pulmonary veins between paroxysmal and persistent atrial fibrillation |
| title_full_unstemmed | Comparison of the electrophysiological properties of the pulmonary veins between paroxysmal and persistent atrial fibrillation |
| title_short | Comparison of the electrophysiological properties of the pulmonary veins between paroxysmal and persistent atrial fibrillation |
| title_sort | comparison of the electrophysiological properties of the pulmonary veins between paroxysmal and persistent atrial fibrillation |
| topic | atrial fibrillation electrophysiological study low‐voltage areas pulmonary vein substrate |
| url | https://doi.org/10.1002/joa3.12981 |
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